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Pancreatic sterol ester hydrolase Reversal of the reaction by bile salt
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1971Abstract Dog pancreatic juice caused esteriucation of free cholesterol and oleic acid in a substrate prepared from myelin figures of cholesterol, water and oleic acid. Bile salt was required for optimum activity, but if it was increased above a certain level, hydrolysis of esters occurred.
L A, Kelly, H A, Newman
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Bile salt independent retinyl ester hydrolases in the bovine eye
Brain Research Bulletin, 1992Homogenates of bovine neuroretina and retinal pigment epithelium (RPE) were incubated with 11-cis and all-trans retinyl palmitate to study retinyl ester hydrolysis. The highest activity was found in RPE when 11-cis retinyl palmitate served as substrate (Km = 7.8 microM and Vmax = 44.8 pmol/min/mg).
A T, Tsin, D W, Malsbury
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Molecular features of bile salt hydrolases and relevance in human health
Biochimica et Biophysica Acta (BBA) - General Subjects, 2017Bile salt hydrolase (BSH) enzyme is responsible for the de-conjugation of bile salts by commensal bacteria, thus playing a vital role in their colonization and survival in the mammalian intestine and determination of their probiotic potential. Further, bile deconjugation also leads to lowering of cholesterol and alterations in energy homeostasis, thus ...
Deepak, Chand +5 more
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Proceedings of the National Academy of Sciences of the United States of America, 2021
Sarah O'Flaherty +2 more
exaly
Sarah O'Flaherty +2 more
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Identifying a Novel Bile Salt Hydrolase from the Keystone Gut Bacterium Christensenella minuta
Microorganisms, 2021Sandrine Claus +2 more
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