Results 41 to 50 of about 8,384,443 (422)
De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function. [PDF]
The splicing regulator Polypyrimidine Tract Binding Protein (PTBP1) has four RNA binding domains that each binds a short pyrimidine element, allowing recognition of diverse pyrimidine-rich sequences.
Black, Douglas L+5 more
core +4 more sources
IGA MULTIPLE MYELOMA ASSESMENT WITH HEVYLITE ASSAY
Introduction: A key element on Multiple Myeloma (MM) evaluation is the quantification of monoclonal proteins. Current techniques include Serum Protein Electrophoresis (SPE), Immunofixation (IFE) and Free Light Chain Assay (FLC, Freelite).
G Virginia+3 more
doaj
Interaction of antithrombin III with surface-immobilized albumin-heparin conjugates [PDF]
The interaction between antithrombin III (ATIII) and albumin-heparin conjugates covalently coupled onto carboxylated polystyrene beads either in buffer containing albumin or in plasma was studied using 14C-labeled ATIII.
Delden, C.J. van+2 more
core +2 more sources
JASPAR 2020: update of the open-access database of transcription factor binding profiles
JASPAR (http://jaspar.genereg.net) is an open-access database of curated, non-redundant transcription factor (TF)-binding profiles stored as position frequency matrices (PFMs) for TFs across multiple species in six taxonomic groups.
O. Fornes+18 more
semanticscholar +1 more source
Salvage of endogenous immunoglobulin G (IgG) by the neonatal Fc receptor (FcRn) is implicated in many clinical areas, including therapeutic monoclonal antibody kinetics, patient monitoring in IgG multiple myeloma, and antibody-mediated transplant ...
Felicity Kendrick+4 more
doaj +1 more source
Binding entanglement channels [PDF]
We define the binding entanglement channel as the quantum channel through which quantum information cannot be reliably transmitted, but which can be used to share bound entanglement. We provide a characterization of such class of channels.
Michał Horodecki+3 more
core +2 more sources
Chaperone assisted translocation [PDF]
We investigate the translocation of a stiff polymer through a nanopore in a membrane, in the presence of binding particles (chaperones) that bind reversibly to the polymer on both sides of the membrane. A bound chaperone covers one (univalent binding) or many (multivalent binding) binding sites.
arxiv +1 more source
Intrinsically Disordered C-Terminal Tails of \u3cem\u3eE. coli\u3c/em\u3e Single-Stranded DNA Binding Protein Regulate Cooperative Binding to Single-Stranded DNA [PDF]
The homotetrameric Escherichia coli single-stranded DNA binding protein (SSB) plays a central role in DNA replication, repair and recombination. E. coli SSB can bind to long single-stranded DNA (ssDNA) in multiple binding modes using all four subunits ...
Antony, Edwin+7 more
core +2 more sources
Nonspecific transcription factor-DNA binding influences nucleosome occupancy in yeast [PDF]
Quantitative understanding of the principles regulating nucleosome occupancy on a genome-wide level is a central issue in eukaryotic genomics. Here, we address this question using budding yeast, Saccharomyces cerevisiae, as a model organism. We perform a genome-wide computational analysis of nonspecific transcription factor (TF)-DNA binding free energy
arxiv +1 more source
Prior to the use of Arabidopsis ( Arabidopsis thaliana ) as a model genetic system, there was little progress made in identifying the molecular structures of hormone receptors in plants. Over the past decade with Arabidopsis leading the foray, we now know the structures of the receptors ...
Alan M. Jones, Michael R. Sussman
openaire +3 more sources