Results 221 to 230 of about 8,730,538 (402)

MicroRNA Binding Site Polymorphisms in Hepatocellular Carcinoma: Implications for Pathogenesis, Prognosis, and Therapeutic Response. [PDF]

Int J Genomics
Rezapour S, Mohammadi FK, Darweesh M, Mohammadi S, Afshar S.   +4 more
europepmc   +1 more source

The MAM (Meprin/A5-protein/PTPmu) Domain Is a Homophilic Binding Site Promoting the Lateral Dimerization of Receptor-like Protein-tyrosine Phosphatase μ [PDF]

, 2004
Valeriu B. Cismasiu, Stefan A. Denes, Helmut Reiländer, Hartmut Michel, Stefan E. Szedlacsek   +4 more
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

A specific binding site for K+ channel openers in rat aorta.

, 1992
K.M. Bray, Ulrich Quast
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Solvation Energetic Costs of Cognate Binding Site Formation. [PDF]

J Chem Inf Model
Ji Y, Molino V, Ramsey S, Kurtzman T.
europepmc   +1 more source

Spectroscopic characterization of the warfarin drug-binding site of folded and unfolded human serum albumin anchored on gold nanoparticles: effect of bioconjugation on the loading capacity

, 2018
Saba A. J. Sulaiman, Tanujjal Bora, Osama K. Abou‐Zied   +2 more
openalex   +1 more source

A Phosphatidylserine-binding Site in the Cytosolic Fragment of Clostridium sordellii Lethal Toxin Facilitates Glucosylation of Membrane-bound Rac and Is Required for Cytotoxicity [PDF]

, 2004
Bruno Mesmin, Karine Robbe-Sermesant, Blandine Geny, Frédéric Luton, Gérard Brandolin, Michel R. Popoff, Bruno Antonny   +6 more
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Isoxazole-Based Compounds Targeting the Taxane-Binding Site of Tubulin. [PDF]

Arch Pharm (Weinheim)
Peřina M, Kiss MA, Bělíček J, Vojáčková V, Veselá D, Minorics R, Zupko I, Frank É, Jorda R.   +8 more
europepmc   +1 more source