Results 231 to 240 of about 8,730,538 (402)

The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion [PDF]

, 2015
Gabriele Giachin, Phuong Thao, Thanh Hoa Tran, Giulia Salzano, Federico Benetti, Valentina Migliorati, Alessandro Arcovito, S. Della Longa, Giordano Mancini, P. D’Angelo, Giuseppe Legname   +10 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

HolomiRA: a reproducible pipeline for miRNA binding site prediction in microbial genomes. [PDF]

BMC Bioinformatics
Bruscadin JJ, Cardoso TF, Conteville LC, da Silva JV, Ibelli AMG, Pena GAC, Porto T, de Oliveira PSN, Andrade BGN, Zerlotini A, Regitano LCA.   +10 more
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

MPBind: a multitask protein binding site predictor using protein language models and equivariant GNNs. [PDF]

Bioinformatics
Wang Y, Boadu F, Cheng J.
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Designing small molecules targeting a cryptic RNA binding site through base displacement. [PDF]

Nat Chem Biol
Olenginski LT, Wierzba AJ, Laursen SP, Batey RT.   +3 more
europepmc   +1 more source

The binding of cyclic AMP receptor protein to two lactose promoter sites is not cooperative in vitro

, 1991
Janette M. Hudson, Michael G. Fried
openalex   +2 more sources

Dealing with stable structures at ribosome binding sites: Bacterial translation and ribosome standby [PDF]

, 2007
Cecilia Unoson, E. Gerhart H. Wagner
openalex   +1 more source

How insulin engages its primary binding site on the insulin receptor

Nature, 2013
J. Menting, J. Whittaker, M. Margetts, L. Whittaker, G.K.-W. Kong, Brian J. Smith, C. J. Watson, L. Žáková, Emília Kletvíková, J. Jiráček, S. J. Chan, D. Steiner, G. Dodson, A. Brzozowski, M. Weiss, C. Ward, M. Lawrence   +16 more
semanticscholar   +1 more source