Results 231 to 240 of about 2,892,311 (358)

Cleavage of Human Cls̄ by Proteolytic Enzymes: Evidence for a C4-Binding Site of Cls̄ Distinct from the Catalytic Center [PDF]

, 1971
Sheldon B. Taubman, Irwin H. Lepow
openalex   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Local and Global Breathing Motions Prime the Access to Buried Binding Site in an Antibiotic-Sequestering Protein. [PDF]

ACS Bio Med Chem Au
Natarajan L, Loginov D, Kadek A, Man P, Naganathan AN.   +4 more
europepmc   +1 more source

Structure of the antithrombin-binding site in heparin. [PDF]

, 1979
Ulf Lindahl, G. Bäckström, Magnus Höök, L Thunberg, L Å Fransson, Alfred Linker   +5 more
openalex   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

One-Size-Fits-All: A Universal Binding Site for Single-Layer Metal Cluster Self-Assembly. [PDF]

Adv Sci (Weinh)
Kohlrausch EC, Ghaderzadeh S, Aliev GN, Popov I, Saad F, Alharbi E, Ramasse QM, Rance GA, Danaie M, Thangamuthu M, Young M, Plummer R, Morgan DJ, Theis W, Besley E, Khlobystov AN, Alves Fernandes J.   +16 more
europepmc   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Distribution of RNA Polymerase Binding Sites in Fractionated Chromatin

, 1974
Robert T. Simpson
openalex   +1 more source

Structural and functional analysis of Bacillus sarcosine oxidase and its activity toward cyclic imino acids

FEBS Open Bio, EarlyView.
Sarcosine oxidase from Bacillus sp. (SoxB) recognizes l‐proline (l‐Pro), d‐proline (d‐Pro), and l‐thioproline (l‐Tpr) as minor substrates. In this study, we measured their absorption spectra, determined the crystal structures of their enzyme complexes, and performed site‐directed mutagenesis of key residues.
Yuqi Zhang, Yoshitaka Nakajima, Masae Kurobe, Tsutomu Nakamura, Tomoki Himiyama, Yoshiaki Nishiya   +5 more
wiley   +1 more source

Benchmarking Zinc-Binding Site Predictors: A Comparative Analysis of Structure-Based Approaches. [PDF]

J Chem Inf Model
Ciofalo C, Laveglia V, Andreini C, Rosato A.   +3 more
europepmc   +1 more source