Results 21 to 30 of about 1,463,984 (318)
The metal binding site of zoocin A [PDF]
JBIC Journal of Biological Inorganic Chemistry, 2008 Direct metal analysis of the bacteriolytic exoenzyme zoocin A failed to unequivocally identify a putative metal cofactor; hence, indirect experiments utilizing NMR were undertaken to settle this question. Cd(2+) as a surrogate metal ion was reconstituted into EDTA-treated, metal-free recombinant zoocin, and (113)Cd-NMR was employed to explore binding ...
Gary L. Sloan +3 more
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Spatial Layouts of Low‐Entropy Hydration Shells Guide Protein Binding
Global Challenges, 2023 Protein–protein binding enables orderly biological self‐organization and is therefore considered a miracle of nature. Protein‒protein binding is driven by electrostatic forces, hydrogen bonding, van der Waals force, and hydrophobic interactions.
Lin Yang +9 more
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Frontiers in Pharmacology, 2022 The identification of similar three-dimensional (3D) amino acid patterns among different proteins might be helpful to explain the polypharmacological profile of many currently used drugs.
Alejandro Valdés-Jiménez +11 more
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Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023 Introduction: Clonal plasma cells secrete immunoglobulins, each with the exact same amino acid sequence, that are referred to as monoclonal immunoglobulins.
David R. Barnidge +3 more
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Anais da Academia Brasileira de Ciências, 2015 RESUMO Dois genes de α-actina do peixe Leporinus macrocephalus, referindo-se aos tecidos musculares branco e vermelho, foram isolados. Isoformas de actinas, que principalmente diferiram por uma substituição Ser/Ala155, podem ter uma significância ...
FERNANDA A. ALVES-COSTA +2 more
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Frontiers in Immunology, 2020 Helminths develop strategies to escape host immune responses that facilitate their survival in the hostile host immune environment. Trichinella spiralis, a tissue-dwelling nematode, has developed a sophisticated strategy to escape complement attack.
Shuai Shao +7 more
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Molecules, 2023 The interaction of indomethacin with human serum albumin (HSA) has been studied here considering the primary and secondary binding sites. The Stern–Volmer plots were linear in the lower concentration range of indomethacin while a downward curvature was ...
Mohd Sajid Ali +5 more
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Ethanol binding sites on proteins
Journal of Molecular Graphics and Modelling, 2017 This study is on the analysis of ethanol binding sites on 3D structures of nonredundant proteins from the Protein Data Bank. The only one amino acid residue that is significantly overrepresented around ethanol molecules is Tyr. There are usually two or more Tyr residues in the same ethanol binding site, while residues of Thr, Asp and Gln are ...
Khrustalev, V. V. +2 more
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A client‐binding site of Cdc37 [PDF]
The FEBS Journal, 2005 The molecular chaperone Hsp90 is distinct from Hsp70 and chaperonin in that client proteins are apparently restricted to a subset of proteins categorized as cellular signaling molecules. Among these, many specific protein kinases require the assistance of Hsp90 and its co‐chaperone Cdc37/p50 for their biogenesis.
Kazuya Terasawa, Yasufumi Minami
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Promiscuity of the Euonymus Carbohydrate-Binding Domain
Biomolecules, 2012 Plants synthesize small amounts of carbohydrate-binding proteins on exposure to stress. For example, on exposure to drought, high salt, wounding and by treatment with some plant hormones or by pathogen attack. In contrast to the ‘classical’ plant lectins
Els J.M. Van Damme, Elke Fouquaert
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