Results 211 to 220 of about 2,663,361 (333)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

CH-π interactions confer orientational flexibility in protein-carbohydrate binding sites. [PDF]

J Biol Chem
Keys AM, Kastner DW, Kiessling LL, Kulik HJ.   +3 more
europepmc   +1 more source

Cardiac glycoside binding sites in cultured heart muscle cells [PDF]

, 1984
Erdmann, E., Krawietz, W., Wagenknecht, B., Werdan, K., Zwißler, Bernhard   +4 more
core   +1 more source

Faculty Opinions recommendation of Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.

, 2008
Titia K. Sixma
openalex   +2 more sources

LY2087101 and dFBr share transmembrane binding sites in the (α4)3(β2)2 Nicotinic Acetylcholine Receptor [PDF]

, 2018
Farah Deba, Hamed I. Ali, Abisola Tairu, Kara Ramos, Jihad Ali, Ayman K. Hamouda   +5 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites. [PDF]

Mol Cancer Ther
Wu T, Yang Z, Tang S, Yuan H, Liu Y, Li H, Liu N, Huang Z, Chen Y, Zhou Z.   +9 more
europepmc   +1 more source

Bayesian multiple-instance motif discovery with BAMBI: inference of recombinase and transcription factor binding sites [PDF]

, 2011
Guido H. Jajamovich, Xiaodong Wang, Adam P. Arkin, Michael S. Samoilov   +3 more
openalex   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Simultaneous ligand binding to intact and partially formed ATP-binding sites in the hexameric termination factor Rho. [PDF]

J Biol Chem
Billings TD, Baker K, Lacey P, Benedek MJ, Muzquiz R, Wysocki VH, Foster MP.   +6 more
europepmc   +1 more source