Results 221 to 230 of about 8,224,245 (384)

Stimulation of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and malic enzyme by L-triiodothyronine. Characteristics of the response with specific nuclear thyroid hormone binding sites fully saturated. [PDF]

, 1977
J H Oppenheimer, Ermelinda Santos Silva, Harold L. Schwartz, Martin I. Surks   +3 more
openalex   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

FEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian, Di Liu, Bing Liu, Yu Lan, Jie Zhou   +4 more
wiley   +1 more source

Sequence, structure, and affinity of miR-34a binding sites determine repression efficacy. [PDF]

Nucleic Acids Res
Sweetapple L, Kosek DM, Banijamali E, Becker W, Müller J, Karadiakos C, Baronti L, Guzzetti I, Schritt D, Chen A, Andersson ER, Petzold K.   +11 more
europepmc   +1 more source

Synthesis of 4-bromoacetamidoestrone methyl ether and study of the steroid binding site of human placental estradiol 17beta-dehydrogenase.

, 1978
Y.M. Bhatnagar, Chang-Chen Chin, James C. Warren   +2 more
openalex   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Master transcription-factor binding sites constitute the core of early replication control elements. [PDF]

EMBO J
Turner JL, Hinojosa-Gonzalez L, Sasaki T, Uchino S, Vouzas A, Soto MS, Chakraborty A, Alexander KE, Fitch CA, Brown AN, Ay F, Gilbert DM.   +11 more
europepmc   +1 more source

Evidence That Tetrodotoxin and Saxitoxin Act at a Metal Cation Binding Site in the Sodium Channels of Nerve Membrane [PDF]

, 1974
Richard A. Henderson, J. M. Ritchie, Gary R. Strichartz   +2 more
openalex   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

FEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper, Sridhar Sreeramulu, Benjamin T. Lanham, Elizabeth M. Engle, David Fushman, Harald Schwalbe   +5 more
wiley   +1 more source

Mapping the space of protein binding sites with sequence-based protein language models. [PDF]

Bioinformatics
Oruç T, Kadukova M, Davies TG, Verdonk M, Poelking C.   +4 more
europepmc   +1 more source

A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2

Nature, 2020
R. Shi, Chao Shan, Xiaomin Duan, Zhihai Chen, Peipei Liu, Jinwen Song, Tao Song, Xiaoshan Bi, Chao Han, Lian-ao Wu, G. Gao, Xue Hu, Yanan Zhang, Z. Tong, Weijing Huang, William J. Liu, Guizhen Wu, Bo Zhang, Lan Wang, J. Qi, H. Feng, Fu-Sheng Wang, Qihui Wang, G. Gao, Zhiming Yuan, Jinghua Yan   +25 more
semanticscholar   +1 more source