Results 11 to 20 of about 252,132 (169)

Neuroprotection with Bioactive Compounds

Nutrients, 2023
Bioactive compounds are found in foods in small quantities and represent extra nutritional constituents known to exert beneficial effects on health beyond their nutritional value [...]
Carmen del Río, Antonio Segura-Carretero   +1 more
openaire   +2 more sources

Pharmacological and Therapeutic Potential of Myristicin: A Literature Review

Molecules, 2021
Natural products have been used by humanity for many centuries to treat various illnesses and with the advancement of technology, it became possible to isolate the substances responsible for the beneficial effects of these products, as well as to ...
Elisa Frederico Seneme, Daiane Carla dos Santos, Evelyn Marcela Rodrigues Silva, Yollanda Edwirges Moreira Franco, Giovanna Barbarini Longato   +4 more
doaj   +1 more source

Evaluation of the Antimicrobial Capacity of Bacteria Isolated from Stingless Bee (Scaptotrigona aff. postica) Honey Cultivated in Açai (Euterpe oleracea) Monoculture

Antibiotics, 2023
Many antimicrobial compounds have been seeking to protect the human body against pathogenic microbial infections. In recent times, there has been considerable growth of pathogens resistant to existing drugs due to the inappropriate use of antibiotics. In
Iago Castro da Silva, Eveson Oscar Almeida Conceição, Daniel Santiago Pereira, Hervé Rogez, Nilton Akio Muto   +4 more
doaj   +1 more source

Vaccine-induced immune thrombotic thrombocytopenia after ChAdOx1 nCoV-19 vaccine in an older patient: Minireview and a case report

Journal of Infection and Public Health, 2022
Rare cases of unusual thrombosis and thrombocytopenia after administration of the ChAdOx1 nCoV-19 vaccine (AstraZeneca) have been reported. The unusual symptoms are called vaccine-induced immune thrombotic thrombocytopenia (VITT). In the present study, a
Paulo Queiroz Luciano, Renan Binatti, André Rodrigues Sodré, Sérgio Roberto Zajac, Fernando Augusto Lima Marson, Manoela Marques Ortega   +5 more
doaj   +1 more source

Antibiotic Acyldepsipeptides Stimulate the Streptomyces Clp-ATPase/ClpP Complex for Accelerated Proteolysis

mBio, 2022
Clp proteases consist of a proteolytic, tetradecameric ClpP core and AAA+ Clp-ATPases. Streptomycetes, producers of a plethora of secondary metabolites, encode up to five different ClpP homologs, and the composition of their unusually complex Clp ...
Laura Reinhardt, Dhana Thomy, Markus Lakemeyer, Linda Maria Westermann, Joaquin Ortega, Stephan A. Sieber, Peter Sass, Heike Brötz-Oesterhelt   +7 more
doaj   +1 more source

Effects of Myristicin in Association with Chemotherapies on the Reversal of the Multidrug Resistance (MDR) Mechanism in Cancer

Pharmaceuticals, 2022
A range of drugs used in cancer treatment comes from natural sources. However, chemotherapy has been facing a major challenge related to multidrug resistance (MDR), a mechanism that results in a decrease in the intracellular concentration of ...
Elisa Frederico Seneme, Daiane Carla dos Santos, Carolina Afonso de Lima, Ícaro Augusto Maccari Zelioli, Juliana Mozer Sciani, Giovanna Barbarini Longato   +5 more
doaj   +1 more source

Anti-Inflammatory Activity of Pequi Oil (Caryocar brasiliense): A Systematic Review

Pharmaceuticals, 2023
Disorders in the inflammatory process underlie the pathogenesis of numerous diseases. The utilization of natural products as anti-inflammatory agents is a well-established approach in both traditional medicine and scientific research, with studies ...
Vitória R. P. Silva, Andréia C. Pinheiro, Alicia S. Ombredane, Natália Ornelas Martins, Glécia V. S. Luz, Marcella L. B. Carneiro, Graziella A. Joanitti   +6 more
doaj   +1 more source

Dietary polyphenols and their relationship to the modulation of non-communicable chronic diseases and epigenetic mechanisms: A mini-review

Food Chemistry: Molecular Sciences, 2023
Chronic Non-Communicable Diseases (NCDs) have been considered a global health problem, characterized as diseases of multiple factors, which are developed throughout life, and regardless of genetics as a risk factor of important relevance, the increase in
Felipe Tecchio Borsoi, Iramaia Angélica Neri-Numa, Williara Queiroz de Oliveira, Fabio Fernandes de Araújo, Glaucia Maria Pastore   +4 more
doaj   +1 more source

The association of a single-nucleotide variant in the microRNA-146a with advanced colorectal cancer prognosis

Tumor Biology, 2020
The aim of this study was to evaluate the association of single-nucleotide variant n.60G>C (rs2910164) of microRNA (miR)-146a, related to suppressing of BRCA1/2 DNA repair protein, with the risk and survival of colorectal cancer patients, as well as miR ...
Jéssica Silva dos Santos, Gabriella Lucatto Zunta, Amanda Binatto Negrini, Marina Silva Guinda Ribeiro, Carlos Augusto Real Martinez, Marcelo Lima Ribeiro, Gustavo Jacob Lourenço, Manoela Marques Ortega   +7 more
doaj   +1 more source

Natural Plant Compounds: Does Caffeine, Dipotassium Glycyrrhizinate, Curcumin, and Euphol Play Roles as Antitumoral Compounds in Glioblastoma Cell Lines?

Frontiers in Neurology, 2022
Many plant-derived compounds are shown to be promising antitumor therapeutic agents by enhancing apoptosis-related pathways and cell cycle impairment in tumor cells, including glioblastoma (GBM) cell lines. We aimed to review four natural plant compounds
Gabriel Alves Bonafé, Matheus Negri Boschiero, André Rodrigues Sodré, Jussara Vaz Ziegler, Thalita Rocha, Manoela Marques Ortega   +5 more
doaj   +1 more source