Results 91 to 100 of about 608,275 (163)

Anti-HIV-1 Activity of the Integrase Strand Transfer Inhibitor ACC017

open access: yesViruses
HIV-1 integrase strand transfer inhibitors (INSTIs) are pivotal to antiretroviral therapy. However, the emergence of drug-resistant mutations necessitates the development of new agents. Here, we present ACC017 as a novel INSTI candidate.
Meng-Di Ma   +8 more
doaj   +1 more source

A Tachyplesin Antimicrobial Peptide from Theraphosidae Spiders with Potent Antifungal Activity Against Cryptococcus neoformans

open access: yesMicroorganisms
The venoms of Theraphosidae spiders have evolved into diverse natural pharmacopeias through selective pressures. Cryptococcus neoformans is a global health threat that frequently causes life-threatening meningitis and fungemia, particularly in ...
Brenda B. Michira   +10 more
doaj   +1 more source

Bioactive Food Peptides in Health and Disease

open access: yes, 2013
"Bioactive Food Peptides in Health and Disease" highlights recent developments on bioactive food peptides for the promotion of human health and the prevention/management of chronic diseases.

core   +1 more source

Bioactive Peptides in Milk Products.

open access: yes, 2000
Some peptides produced in vitro or in vivo by enzymatic hydrolysis of caseins and whey protein can affect some biological functions of the body and therefore they are called bioactive peptides.
P. Resmini   +5 more
core   +1 more source

Milk-derived bioactive peptides

open access: yes
Bioactive peptides are the functional concept that refer to fragments of proteins that provide both functional and nutritional benefits as a functional component. Milk has been widely exploited as a source of diverse bioactive peptides.
Phareichon Kashung, Devi Karuthapandian
core   +1 more source

Increased cAMP-PKA signaling pathway activation is involved in up-regulation of CTLA-4 expression in CD4+ T cells in acute SIVmac239-infected Chinese rhesus macaques

open access: yesVirus Research
Human immunodeficiency virus-1 (HIV-1) infection can cause chronic activation, exhaustion, and anergy of the immune system. Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is an immune checkpoint molecule, which plays an important role in immune ...
Ren-Rong Tian   +4 more
doaj   +1 more source

Limited restoration of T cell subset distribution and immune function in older people living with HIV-1 receiving HAART

open access: yesImmunity & Ageing
Background Older people living with HIV-1 (PLWH) experience a dual burden from the combined effects of aging and HIV-1 infection, resulting in significant immune dysfunction. Despite receiving HAART, immune reconstitution is not fully optimized.
Na Li   +9 more
doaj   +1 more source

Establishment and evaluation of a predictive model for immune reconstitution in people living with HIV after antiretroviral therapy

open access: yesBMC Infectious Diseases
Background Achieving complete immune reconstitution (CIR) in people living with human immunodeficiency virus (PLWH) following antiretroviral therapy (ART) is essential for preventing acquired immunodeficiency syndrome (AIDS) progression and improving ...
Na Li   +10 more
doaj   +1 more source

Research Progress on Bioactive Peptides From Diverse Sources: Preparation, Structure-Activity Relationship, and Applications. [PDF]

open access: yesJ Food Sci
Liang PR   +10 more
europepmc   +1 more source

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