Results 81 to 90 of about 171,521 (301)

Natural product diversity of actinobacteria in the Atacama Desert [PDF]

, 2018
Natural Product diversityPeer reviewedPublisher ...
Ebel, Rainer, Jaspars, Marcel, Rateb, Mostafa E.   +2 more
core   +3 more sources

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Self-assembly of Fmoc-tetrapeptides based on the RGDS cell adhesion motif [PDF]

, 2011
Self-assembly in aqueous solution has been investigated for two Fmoc [Fmoc ¼ N-(fluorenyl)-9-methoxycarbonyl] tetrapeptides comprising the RGDS cell adhesion motif from fibronectin or the scrambled sequence GRDS.
Alemán, Carlos, Castelletto, Valeria, Cheng, Ge, Hamley, Ian W., Hicks, Matthew R., López-Pérez, Daniel E., Moulton, Claire M., Revilla-López-Pérez, Guillermo, Rodger, Alison   +8 more
core   +1 more source

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Thermoregulatory role of ghrelin in the induction of torpor under a restricted feeding condition

Scientific Reports, 2021
Ghrelin, a circulating orexigenic hormone secreted from the stomach, stimulates appetite and food intake by activating the hypothalamic arcuate nucleus. Administration of exogenous ghrelin exerts anabolic effects, causing weight gain, increased adiposity,
Takahiro Sato, Kanae Oishi, Daisuke Koga, Takanori Ida, Yusuke Sakai, Kenji Kangawa, Masayasu Kojima   +6 more
doaj   +1 more source

Novel antioxidant and anti-inflammatory peptides from the Siamese crocodile (Crocodylus siamensis) hemoglobin hydrolysate [PDF]

, 2017
Novel antioxidant and anti-inflammatory peptides were isolated from hydrolysates of Siamese crocodile (Crocodylus siamensis) hemoglobin. C. siamensis hemoglobin hydrolysates (CHHs) were obtained by pepsin digestion at different incubation times (2, 4, 6,
Jangpromma, Nisachon, Khunkitti, Watcharee, Klaynongsruang, Sompong, Lueangsakulthai, Jiraporn, McKendrick, John E., Phosri, Santi, Temsiripong, Theeranan, Theansungnoen, Tinnakorn   +7 more
core   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Molecular basis for heat desensitization of TRPV1 ion channels

Nature Communications, 2019
The heat-sensitive ion channel TRPV1 is essential to temperature sensing in mammals and other animals. Here the authors find that the platypus form of TRPV1 does not desensitize, identify the mechanism underlying this property, and show that knock-in of ...
Lei Luo, Yunfei Wang, Bowen Li, Lizhen Xu, Peter Muiruri Kamau, Jie Zheng, Fan Yang, Shilong Yang, Ren Lai   +8 more
doaj   +1 more source

The Lymnaea Cardioexcitatory Peptide (LyCEP) Receptor: A G-Protein–Coupled Receptor for a Novel Member of the RFamide Neuropeptide Family [PDF]

, 1998
A novel G-protein–coupled receptor (GRL106) resembling neuropeptide Y and tachykinin receptors was cloned from the molluscLymnaea stagnalis. Application of a peptide extract from the Lymnaea brain to Xenopus oocytes expressing GRL106 activated a calcium ...
Burke, Julian F, Cox, Kingsley J A, Geraerts, Wijnand P M, Hermann, Petra M, Knol, Jaco C, Meyerhof, Wolfgang, Planta, Rudi J, Richter, Dietmar, Smit, August B, Tensen, Cornelius P, van der Schors, Roel C, van Heerikhuizen, Harm, van Minnen, Jan, Vreugdenhil, Erno   +13 more
core   +7 more sources

Fibrin association at hybrid biointerfaces made of clot-binding peptides and polythiophene [PDF]

, 2016
The properties as biointerfaces of electroactive conducting polymer-peptide biocomposites formed by poly(3,4-ethylenedioxythiophene) (PEDOT) and CREKA or CR(NMe)EKA peptide sequences (where Glu has been replaced by N-methyl-Glu in the latter) have been ...
Agemy, Aradilla, Bhattacharyya, Blombäk, Boccaccio, Carr, Coelho, del Valle, Dolatshahi-Pirouz, Doolittle, Doolittle, Fabregat, Fabregat, Flamia, Groenendaal, Groenendaal, Gunawan, Guo, Hamedi, Hamzah, Han, Hoffman, Huang, Kirchmeyer, Li, Longa, López-Pérez, Maione, O'Brien, Oss, Pasqualini, Peters, Pérez-Madrigal, Pérez-Madrigal, Romero, She, Shi, Simberg, Soto-Delgado, Stevens, Wasilewska, Weisel, Weisel, Wong, Wu, Yuan, Zanuy, Zanuy, Zanuy, Zanuy, Zavyalova   +50 more
core   +4 more sources