Results 101 to 110 of about 1,531,106 (344)
Novel Sodium Channel Inhibitor From Leeches
Frontiers in Pharmacology, 2018 Considering blood-sucking habits of leeches from surviving strategy of view, it can be hypothesized that leech saliva has analgesia or anesthesia functions for leeches to stay undetected by the host. However, no specific substance with analgesic function
Gan Wang +16 more
doaj +1 more source
Conductive Hydrogels for Exogenous Sensing and Cell Fate Control
Advanced Materials, EarlyView.We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar +15 more
wiley +1 more source
Bioactive peptides from venoms against glioma progression
, 2022 Venoms are complex mixtures of different molecules and ions. Among them, bioactive peptides have been found to affect cancer hallmarks, such as cell proliferation, cell invasion, cell migration, and can also modulate the immune response of normal and ...
Majc, Bernarda +4 more
core +1 more source
Ultra‐High‐Throughput Discovery of Multifunctional Polyphenolic Coatings on Droplet Microarrays
Advanced Materials, EarlyView.An ultra‐high‐throughput (UHT) combinatorial strategy enables the miniaturized synthesis and screening of ≈30 000 polyamine‐polyphenolic (PaPp) coatings using droplet microarrays (DMA). This approach reveals hundreds of previously unknown fluorescent, redox‐active, and antibacterial materials, including multifunctional, cell‐compatible surfaces ...
Vania Tanda Widyaya +11 more
wiley +1 more source
Advanced Materials, EarlyView.This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang +10 more
wiley +1 more source
Thermoregulatory role of ghrelin in the induction of torpor under a restricted feeding condition
Scientific Reports, 2021 Ghrelin, a circulating orexigenic hormone secreted from the stomach, stimulates appetite and food intake by activating the hypothalamic arcuate nucleus. Administration of exogenous ghrelin exerts anabolic effects, causing weight gain, increased adiposity,
Takahiro Sato +6 more
doaj +1 more source
Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues
Advanced Materials Interfaces, EarlyView.ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike +3 more
wiley +1 more source
, 2021 This study compared protein hydrolysates generated from Rainbow Trout (Oncorhynchus mykiss) by-products and Chlorella (Chlorella sorokiniana), for their functional properties as bioactive peptides.
Fernando, Warnakulasuriya Ranitha Deshapriya
core
Identifying Bioactive Peptides from Poultry By-Products
, 2022 Bioactive peptides derived from food proteins are becoming increasingly popular ingredients due to their beneficial effect on the immune system and other functional properties.
Marina G. Kurbanova +3 more
core +1 more source
Molecular basis for heat desensitization of TRPV1 ion channels
Nature Communications, 2019 The heat-sensitive ion channel TRPV1 is essential to temperature sensing in mammals and other animals. Here the authors find that the platypus form of TRPV1 does not desensitize, identify the mechanism underlying this property, and show that knock-in of ...
Lei Luo +8 more
doaj +1 more source