Results 1 to 10 of about 803,201 (379)

Polyphenols and Human Health: The Role of Bioavailability

Nutrients, 2021
Polyphenols are a group of phytochemicals with potential health-promoting effects. They are classified as flavonoid (flavonols, flavanols, flavones, flavanones, isoflavones, and anthocyanins) and non-flavonoid molecules (phenolic acids, hydroxycinnamic ...
Chiara Di Lorenzo, F. Colombo, S. Biella, C. Stockley, P. Restani   +4 more
semanticscholar   +1 more source

A Review on Toxicity and Challenges in Transferability of Surface-functionalized Metallic Nanoparticles from Animal Models to Humans

BIO Integration, 2021
The unique size and surface morphology of nanoparticles (NPs) have substantially influenced all aspects of human life, making nanotechnology a novel and promising field for various applications in biomedical sciences.
Muhammad Arif Asghar, Rabia Ismail Yousuf, Muhammad Harris Shoaib, Muhammad Asif Asghar, Nazish Mumtaz   +4 more
doaj   +1 more source

Cyclodextrin Inclusion Complexes for Improved Drug Bioavailability and Activity: Synthetic and Analytical Aspects

Pharmaceutics, 2023
Many active pharmaceutical ingredients show low oral bioavailability due to factors such as poor solubility and physical and chemical instability.
Álvaro Sarabia-Vallejo, M. Caja, A. I. Olives, M. A. Martín, J. C. Menéndez   +4 more
semanticscholar   +1 more source

Current Understanding of Polyphenols to Enhance Bioavailability for Better Therapies

Biomedicines, 2023
In recent years, plant polyphenols have become a popular focus for the development of novel functional foods. Polyphenols, a class of bioactive compounds, including flavonoids, phenolic acids, and lignans, are commonly found in plant-based diets with a ...
Mohammad Aatif
semanticscholar   +1 more source

Research Note: Effects of organic zinc on broiler intestinal permeability and integrity in Clostridium perfringens–challenged condition

Poultry Science, 2020
This study evaluates the effects of a zinc–amino acid complex on broiler's intestinal permeability and integrity challenged with Clostridium perfringens.
Jingjing Sun, Cheng Zhang, Bingkun Zhang
doaj   +1 more source

Complete dataset for 2-treatment, 2-sequence, 2-period efavirenz bioequivalence study conducted with nightly dosing

Data in Brief, 2016
The efavirenz pharmacokinetic raw data presented in this article was obtained in an average bioequivalence study between a local brand and Stocrin (Merck Sharp & Dohme, purchased from Australia, batch H009175, expiration date November 2013).
Manuel Ibarra, Laura Magallanes, Marianela Lorier, Marta Vázquez, Pietro Fagiolino   +4 more
doaj   +1 more source

A Hydrophilic Interaction Liquid Chromatography–Tandem Mass Spectrometry Quantitative Method for Determination of Baricitinib in Plasma, and Its Application in a Pharmacokinetic Study in Rats

Molecules, 2020
Baricitinib, is a selective and reversible Janus kinase inhibitor, is commonly used to treat adult patients with moderately to severely active rheumatoid arthritis (RA).
Essam Ezzeldin, Muzaffar Iqbal, Yousif A. Asiri, Azza A Ali, Prawez Alam, Toqa El-Nahhas   +5 more
doaj   +1 more source

Comparative bioavailability of vitamins in human foods sourced from animals and plants

Critical reviews in food science and nutrition, 2023
Vitamins are essential components of enzyme systems involved in normal growth and function. The quantitative estimation of the proportion of dietary vitamins, that is in a form available for utilization by the human body, is limited and fragmentary. This
Sylvia M. S. Chungchunlam, P. Moughan
semanticscholar   +1 more source

Determination of isotretinoin in human plasma: Application to pharmacokinetic study

Bulletin of Faculty of Pharmacy Cairo University, 2012
A simple, rapid, sensitive and accurate HPLC–UV detection method was developed and validated for the determination of isotretinoin in human plasma. The method involves protein precipitation of plasma by acetonitrile using nifedipine as the internal ...
Nisreen F. Abo-Talib, Marwa H. Tammam, Essam E. Hassan   +2 more
doaj   +1 more source

Validated Reversed-Phase Liquid Chromatographic Method with Gradient Elution for Simultaneous Determination of the Antiviral Agents: Sofosbuvir, Ledipasvir, Daclatasvir, and Simeprevir in Their Dosage Forms

Molecules, 2020
A simple, rapid, sensitive, and precise reversed-phase liquid chromatographic method was developed and validated for the simultaneous determination of four direct-acting antivirals, sofosbuvir (SF), ledipasvir (LD), declatasvir (DC), and simeprevir (SM),
Essam Ezzeldin, Nisreen F. Abo-Talib, Marwa H. Tammam, Yousif A. Asiri, Abd El-Galil E. Amr, Abdulrahman A. Almehizia   +5 more
doaj   +1 more source