Results 21 to 30 of about 719,874 (416)

Determination of isotretinoin in human plasma: Application to pharmacokinetic study

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2012
A simple, rapid, sensitive and accurate HPLC–UV detection method was developed and validated for the determination of isotretinoin in human plasma. The method involves protein precipitation of plasma by acetonitrile using nifedipine as the internal ...
Nisreen F. Abo-Talib   +2 more
doaj   +1 more source

Zinc accumulation and utilisation by wine yeasts [PDF]

open access: yes, 2009
The present study has focused on the accumulation of zinc by wine yeast strains of Saccharomyces cerevisiae during fermentation of both grape juice and chemically defined medium with different carbohydrates and at varying levels of zinc. The results have
Bollag, Tatiana   +4 more
core   +1 more source

Bioavailability enhancement

open access: yesWorld Journal of Advanced Research and Reviews, 2023
The rate and extent (amount) of unmodified medication absorption from its dose form is referred to as bioavailability. It is one of the critical criteria for achieving optimal medication concentration in the systemic circulation. Bioavailability is a significant factor of a drug's therapeutic efficacy, which is determined by the drug's solubility in ...
Vaishnavi Tejram Gabhane   +5 more
openaire   +1 more source

Immobilization and assessment of heavy metals in chicken manure compost amended with rice straw-derived biochar

open access: yesEnvironmental Pollutants & Bioavailability, 2021
In this study, a 30-days laboratory experiment was implemented to investigate the impact of additive biochar on the stabilization of heavy metals in chicken manure compost.
Hui Li   +6 more
doaj   +1 more source

Bioavailability of diphenylhydantoin [PDF]

open access: yesClinical Pharmacology & Therapeutics, 1974
A four‐way crossover study was performed in 8 adult volunteers using a Latin square design with 4 groups of 2 subiects arranged in order of increasing body weight. Single 100 mg doses of diphenylhydantoin (DPH) sodium were administered as an aqueous solution (treatment A), the innovator's capsule (treatment B), alld a commercially available generic ...
Albert, Kenneth S.   +4 more
openaire   +4 more sources

Assessment of high fluoride in water sources and endemic fluorosis in the North-Eastern communities of Gombe State, Nigeria

open access: yesEnvironmental Pollutants & Bioavailability, 2021
Fluoride content of drinking water sources in 12 communities in North-Eastern states, Nigeria, was investigation. The fluoride concentration analyses were performed using the SPADNS method according to the standard method for examining water and ...
Abdulmoseen Segun Giwa   +8 more
doaj   +1 more source

Computational model of drug dissolution in the stomach: effects of posture and gastroparesis on drug bioavailability [PDF]

open access: yes, 2022
The oral route is the most common choice for drug administration because of convenience, low cost, and high patient compliance, but is also a complex route. The rate of dissolution and gastric emptying of the dissolved active pharmaceutical ingredient (API) into the duodenum is modulated by factors such as gastric motility, but current in-vitro ...
arxiv   +1 more source

Influence and interactions of multi-factors on the bioavailability of PAHs in compost amended contaminated soils [PDF]

open access: yes, 2014
Compost amendment to contaminated soils is a potential approach for waste recycling and soil remediation. The relative importance and interactions of multiple factors on PAH bioavailability in soils were investigated using conjoint analysis and five-way ...
Coulon, Frederic   +5 more
core   +1 more source

Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies.

open access: yesAmerican Journal of Clinical Nutrition, 2005
Polyphenols are abundant micronutrients in our diet, and evidence for their role in the prevention of degenerative diseases is emerging. Bioavailability differs greatly from one polyphenol to another, so that the most abundant polyphenols in our diet are
C. Manach   +4 more
semanticscholar   +1 more source

Determination of O6-Methylguanine in dried blood spot of breast cancer patients after cyclophosphamide administration

open access: yesHeliyon, 2021
Cyclophosphamide is a nitrogen mustard class of drugs that are often used in cancer chemotherapy. However, the use of Cyclophosphamide in high doses over a long period has been shown to increase the risk of developing secondary cancer.
Yahdiana Harahap   +4 more
doaj  

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