Results 21 to 30 of about 766,095 (388)

State of the Art of Anthocyanins: Antioxidant Activity, Sources, Bioavailability, and Therapeutic Effect in Human Health

open access: yesAntioxidants, 2020
The antioxidant activity of anthocyanins in food is well known. Numerous antioxidant assays have been proposed to measure the capacity of anthocyanins to prevent the oxidation process that naturally occurs. Different solvents, temperatures, and pH levels
Noelia Tena, Julia Martín, A. Asuero
semanticscholar   +1 more source

Dietary Plant Polyphenols: Effects of Food Processing on Their Content and Bioavailability

open access: yesMolecules, 2021
Dietary plant polyphenols are natural bioactive compounds that are increasingly attracting the attention of food scientists and nutritionists because of their nutraceutical properties.
Leila Arfaoui
semanticscholar   +1 more source

Systems biological approach of molecular descriptors connectivity: optimal descriptors for oral bioavailability prediction. [PDF]

open access: yesPLoS ONE, 2012
Poor oral bioavailability is an important parameter accounting for the failure of the drug candidates. Approximately, 50% of developing drugs fail because of unfavorable oral bioavailability.
Shiek S S J Ahmed, V Ramakrishnan
doaj   +1 more source

Zinc accumulation and utilisation by wine yeasts [PDF]

open access: yes, 2009
The present study has focused on the accumulation of zinc by wine yeast strains of Saccharomyces cerevisiae during fermentation of both grape juice and chemically defined medium with different carbohydrates and at varying levels of zinc. The results have
Bollag, Tatiana   +4 more
core   +1 more source

Determination of isotretinoin in human plasma: Application to pharmacokinetic study

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2012
A simple, rapid, sensitive and accurate HPLC–UV detection method was developed and validated for the determination of isotretinoin in human plasma. The method involves protein precipitation of plasma by acetonitrile using nifedipine as the internal ...
Nisreen F. Abo-Talib   +2 more
doaj   +1 more source

UPLC–MS/MS assay for quantification of an inhibitor of kinases (Foretinib) in plasma: Application to a pharmacokinetic study in rats

open access: yesSaudi Pharmaceutical Journal, 2020
Foretinib, an oral multikinase inhibitor, is known to have anti-tumor effects against cancers. The doses and the levels of foretinib vary based on the type of cancer to be treated.
Essam Ezzeldin   +4 more
doaj   +1 more source

Improving Curcumin Bioavailability: Current Strategies and Future Perspectives

open access: yesPharmaceutics, 2021
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is also characterized by problematic drug delivery and scarce bioavailability, representing the main problem related to the use of this compound.
Rita Tabanelli   +2 more
semanticscholar   +1 more source

Differences in reactivation of tuberculosis induced from anti-tnf treatments are based on bioavailability in granulomatous tissue [PDF]

open access: yes, 2007
The immune response to Mycobacterium tuberculosis (Mtb) infection is complex. Experimental evidence has revealed that tumor necrosis factor (TNF) plays a major role in host defense against Mtb in both active and latent phases of infection.
Denise E Kirschner   +7 more
core   +3 more sources

Biomedical Applications and Bioavailability of Curcumin—An Updated Overview

open access: yesPharmaceutics, 2021
Curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa, has been identified as the bioactive compound responsible for numerous pharmacological activities of turmeric, including anticancer, antimicrobial, anti-inflammatory ...
S. Sohn   +8 more
semanticscholar   +1 more source

A Comparative Pharmacokinetics Study of the Anti-Parkinsonian Drug Pramipexole

open access: yesScientia Pharmaceutica, 2016
The present study aimed to compare pharmacokinetic parameters of two pramipexole 0.25 mg formulations in order to show bioequivalence. The study was conducted in a randomized, open-label, two-period, two-sequence, and crossover design, involving 23 ...
Ratih S. I. Putri   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy