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Patented Bioavailability Enhancement Techniques of Silymarin
Recent Patents on Drug Delivery & Formulation, 2010The present article dwells in reviewing critically the patents published mainly on the new emerging trends and techniques for increasing the bioavailability of silymarin, the polyphenolic fraction obtained from the seeds of Silybum marianum. The use of this herb for treating various ailments like hepatitis, cirrhosis, jaundice, mushroom and toxin ...
Shamama, Javed +2 more
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Bioavailability of progesterone enhanced by intranasal spraying
Experientia, 1981The bioavailability of progesterone (P) in terms of area under time-concentration curve and maximal concentration in the serum and cerebrospinal fluid was studied in adult ovariectomized rhesus monkeys following the administration of P as a nasal spray, i.v. or i.m. injections, nasal or eye drops.
G F, David, C P, Puri, T C, Anand Kumar
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Enhanced phenol bioavailability by means of photocatalysis
Biodegradation, 2012Phenol was investigated for the ability of TiO2 photocatalysis to increase its bioavailability as an electron donor for denitrification. The rate of nitrate removal by denitrification was increased by up to 2.6-fold by exposing phenol to photocatalysis for 30 min, although the rate decreased with increasing photocatalysis. The increased denitrification
Jiewei, Wang +4 more
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Enhanced solubility and bioavailability of flurbiprofen by cycloamylose
Archives of Pharmacal Research, 2011The effect of cycloamylose on the aqueous solubility of flurbiprofen was investigated. To improve the solubility and bioavailability of flurbiprofen (poor water solubility), a solid dispersion was spray dried with a solution of flurbiprofen and cycloamylose at a weight ratio of 1:1.
Hyung Hee, Baek +8 more
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Enhancing bioavailability through thermal processing
International Journal of Pharmaceutics, 2013Formulation intervention, through the application of processing technologies, is a requirement for enabling therapy for the vast majority of drugs. Without these enabling technologies, poorly soluble drugs may not achieve therapeutic concentrations in the blood or tissue of interest.
Justin M, Keen +2 more
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Pharmacokinetics and Bioavailability Enhancement of Baicalin: A Review
European Journal of Drug Metabolism and Pharmacokinetics, 2018Baicalin is one of the major bioactive components of Scutellaria radix, a Chinese herb that has been used since ancient times. Baicalin has various pharmacological activities, including antitumor, antimicrobial, and antioxidant, and has wide clinical applications.
Ting, Huang +2 more
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Beta-cyclodextrins enhance bioavailability of pilocarpine
Current Eye Research, 1993Cyclodextrins have been used to improve drug solubility, stability and absorption for oral and parenteral administration. However, their potential for improving ocular drug delivery has received little attention. To evaluate the ability of hydroxypropyl-beta-cyclodextrins to improve ophthalmic drug bioavailability following topical administration, the ...
K A, Freedman, J W, Klein, C E, Crosson
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Bacterial enhancement of contaminant bioavailability
2021Understanding bacterial and contaminant transport in subsurface porous media is critical both in preventing contamination of drinking-water supplies and in successful implementation of bioremediation. Groundwater bioremediation is often limited by inadequate distribution of bacteria within the contaminated sites, which reduces the bioavailability of ...
Rajveer Singh, Mira S. Olson
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Lipid nanoparticles for enhancing oral bioavailability
NanoscaleIn recent studies, lipid nanoparticles have attracted attention as drug delivery systems owing to their preeminent potential in achieving the desired bioavailability of biopharmaceutics (BCS) class II and class IV drugs.
Anushareddy Gangavarapu +5 more
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Approaches for Enhancing the Nutrients Bioavailability
2020Bioavailability is the fraction of a nutrient in the food that is absorbed upon digestion and available for utilization in normal physiological functions. Bioavailability of nutrients especially that of micronutrients from plant based foods is a complex issue and is a concern to the nutritionists and plant breeders who are undertaking nutrient ...
K. Hariprasanna +3 more
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