Results 21 to 30 of about 352,437 (243)

Systems Biology Graphical Notation: Entity Relationship language Level 1 [PDF]

open access: yes, 2009
Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society would not have evolved at the same pace.
Anatoly Sorokin   +5 more
core   +3 more sources

Rational Enzyme Engineering Through Biophysical and Biochemical Modeling [PDF]

open access: yes, 2016
Due to its importance in the pharmaceutical industry, ligand dynamic simulations have experienced a great expansion. Using all-atom models and cutting edge hardware, one can perform non-biased ligand migration, active site search and binding studies.
Acebes, Sandra   +8 more
core   +2 more sources

Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids [PDF]

open access: yes, 2019
Tissue specific extracellular matrices (ECM) provide structural support and enable access to molecular signals and metabolites, which are essential for directing stem cell renewal and differentiation.
Al-Aama, Jumana   +15 more
core   +2 more sources

Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]

open access: yes, 2012
Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core   +2 more sources

Spotting priming-active compounds using parsley cell cultures in microtiter plates

open access: yesBMC Plant Biology, 2023
Background Conventional crop protection has major drawbacks, such as developing pest and pathogen insensitivity to pesticides and low environmental compatibility. Therefore, alternative crop protection strategies are needed. One promising approach treats
Kyra Hoffmann   +6 more
doaj   +1 more source

Improving Haemophilus influenzae Type b Polysaccharide Productivity Through Continuous Culture for Pentavalent Vaccine Manufacturing

open access: yesFermentation
Haemophilus influenzae type b (Hib) is a Gram-negative bacterium that causes severe infections in children under five, especially in developing countries.
Lucas Santos Solidade   +2 more
doaj   +1 more source

Directed evolution for soluble and active periplasmic expression of bovine enterokinase in Escherichia coli

open access: yesScientific Reports, 2022
Bovine enterokinase light chain (EKL) is an industrially useful protease for accurate removal of affinity-purification tags from high-value biopharmaceuticals.
Weiluo Lee   +6 more
doaj   +1 more source

A Green Chemical Approach for the Synthesis of Gold Nanoparticles: Characterization and Mechanistic Aspect [PDF]

open access: yes, 2009
This IRCSET-EMPOWER (Irish Research Council for Science, Engineering and Technology Postdoctoral Research Grant) project aims to improve current methodology for the synthesis of metal nanoparticles (NPs).
Das, Sujoy K., Marsili, Enrico
core   +1 more source

Parallel substrate supply and pH stabilization for optimal screening of E. coli with the membrane-based fed-batch shake flask

open access: yesMicrobial Cell Factories, 2018
Background Screening in the fed-batch operation mode is essential for biological cultivations facing challenges as oxygen limitation, osmotic inhibition, catabolite repression, substrate inhibition or overflow metabolism.
P. Philip   +6 more
doaj   +1 more source

Reduction of dynamical biochemical reaction networks in computational biology [PDF]

open access: yes, 2012
Biochemical networks are used in computational biology, to model the static and dynamical details of systems involved in cell signaling, metabolism, and regulation of gene expression.
Gorban, Alexander N.   +3 more
core   +6 more sources

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