Results 21 to 30 of about 579,757 (320)
iScience, 2022 Summary: In this study, we synthesized and evaluated new photoswitchable ligands for the beta-adrenergic receptors β1-AR and β2-AR, applying an azologization strategy to the first-generation beta-blocker propranolol. The resulting compounds (Opto-prop-1,
Reggie Bosma +14 more
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Utilizing osteocyte derived factors to enhance cell viability and osteogenic matrix deposition within IPN hydrogels [PDF]
, 2020 Many bone defects arising due to traumatic injury, disease, or surgery are unable to regenerate, requiring intervention. More than four million graft procedures are performed each year to treat these defects making bone the second most commonly ...
Hoey, David A. +2 more
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Journal of Biological Engineering, 2022 Background Historically, complex media are used for the cultivation of Gluconobacter oxydans in industry and research. Using complex media has different drawbacks like higher costs for downstream processing and significant variations in fermentation ...
Svenja Battling +7 more
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Energy-based Analysis of Biochemical Cycles using Bond Graphs [PDF]
, 2014 Thermodynamic aspects of chemical reactions have a long history in the Physical Chemistry literature. In particular, biochemical cycles - the building-blocks of biochemical systems - require a source of energy to function.
Crampin, Edmund J., Gawthrop, Peter J.
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On Projection-Based Model Reduction of Biochemical Networks-- Part II: The Stochastic Case [PDF]
, 2014 In this paper, we consider the problem of model order reduction of stochastic biochemical networks. In particular, we reduce the order of (the number of equations in) the Linear Noise Approximation of the Chemical Master Equation, which is often used to ...
Anderson, James, Sootla, Aivar
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Reverse engineering of genetic networks with Bayesian networks [PDF]
, 2003 This paper provides a brief introduction to learning Bayesian networks from gene-expression data. The method is contrasted with other approaches to the reverse engineering of biochemical networks, and the Bayesian learning paradigm is briefly described ...
Husmeier, D.
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Heliyon, 2023 At present lentiviral vector production for cell and gene therapy commonly involves transient plasmid transfection of mammalian cells cultivated in serum-containing media and addition of exogenous nuclease to reduce host cell and plasmid DNA impurities ...
Sadfer Ali +5 more
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Advances in Polymer Technology, 2022 Water flux is one of the most important performance parameters of the reverse osmosis (RO) membrane. The higher water flux means lower energy cost when treating the same volume of feed solution with membrane separation technology.
Zhongyan Chen +5 more
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An extra dimension in protein tagging by quantifying universal proteotypic peptides using targeted proteomics [PDF]
, 2016 The use of protein tagging to facilitate detailed characterization of target proteins has not only revolutionized cell biology, but also enabled biochemical analysis through efficient recovery of the protein complexes wherein the tagged proteins reside ...
De Sutter, Delphine +9 more
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