Results 21 to 30 of about 3,092,070 (229)

Development of a chemically defined medium for Paenibacillus polymyxa by parallel online monitoring of the respiration activity in microtiter plates

BMC Biotechnology, 2023
Background One critical parameter in microbial cultivations is the composition of the cultivation medium. Nowadays, the application of chemically defined media increases, due to a more defined and reproducible fermentation performance than in complex ...
Jennifer Goldmanns, Georg Andreas Röhling, Marie Kristine Lipa, Theresa Scholand, Alexander Deitert, Tobias May, Evangeline Priya Haas, Matthias Boy, Andrea Herold, Jochen Büchs   +9 more
doaj   +1 more source

Biophysical and Biochemical Cues of Biomaterials Guide Mesenchymal Stem Cell Behaviors

Frontiers in Cell and Developmental Biology, 2021
Mesenchymal stem cells (MSCs) have been widely used in the fields of tissue engineering and regenerative medicine due to their self-renewal capabilities and multipotential differentiation assurance.
Jianjun Li, Yufan Liu, Yijie Zhang, B. Yao, Enhejirigala, Zhao Li, Wei Song, Yuzhen Wang, Xianlan Duan, Xingyu Yuan, Xiaobing Fu, Sha Huang   +11 more
semanticscholar   +1 more source

Parallel substrate supply and pH stabilization for optimal screening of E. coli with the membrane-based fed-batch shake flask

Microbial Cell Factories, 2018
Background Screening in the fed-batch operation mode is essential for biological cultivations facing challenges as oxygen limitation, osmotic inhibition, catabolite repression, substrate inhibition or overflow metabolism.
P. Philip, D. Kern, J. Goldmanns, F. Seiler, A. Schulte, T. Habicher, J. Büchs   +6 more
doaj   +1 more source

Directed evolution for soluble and active periplasmic expression of bovine enterokinase in Escherichia coli

Scientific Reports, 2022
Bovine enterokinase light chain (EKL) is an industrially useful protease for accurate removal of affinity-purification tags from high-value biopharmaceuticals.
Weiluo Lee, Subhas Pradhan, Cheng Zhang, Niccolo A. E. Venanzi, Weina Li, Stephen Goldrick, Paul A. Dalby   +6 more
doaj   +1 more source

Plant drought stress tolerance: understanding its physiological, biochemical and molecular mechanisms

Biotechnology & Biotechnological Equipment, 2021
Plants are vulnerable to many environmental constraints which include drought, salinity, extreme temperatures, heavy metals, etc., thereby posing damage to the development and yield of major crops.
Sheikh Shanawaz Bashir, Anjuman Hussain, S. J. Hussain, O. A. Wani, Sheikh Zahid Nabi, N. A. Dar, F. Baloch, Sheikh Mansoor   +7 more
semanticscholar   +1 more source

Type I-F CRISPR-PAIR platform for multi-mode regulation to boost extracellular electron transfer in Shewanella oneidensis

iScience, 2022
Summary: Bio-electrochemical systems are based on extracellular electron transfer (EET), whose efficiency relates to the expression level of numerous genes.
Yaru Chen, Meijie Cheng, Hao Song, Yingxiu Cao   +3 more
doaj  

Systematic evaluation of characteristics of the membrane-based fed-batch shake flask

Microbial Cell Factories, 2017
Background The initial part of process development involves extensive screening programs to identify optimal biological systems and cultivation conditions.
P. Philip, K. Meier, D. Kern, J. Goldmanns, F. Stockmeier, C. Bähr, J. Büchs   +6 more
doaj   +1 more source

Highly efficient fermentation of 5-keto-d-fructose with Gluconobacter oxydans at different scales

Microbial Cell Factories, 2022
Background The global market for sweeteners is increasing, and the food industry is constantly looking for new low-caloric sweeteners. The natural sweetener 5-keto-d-fructose is one such candidate.
Svenja Battling, Tobias Engel, Elena Herweg, Paul-Joachim Niehoff, Matthias Pesch, Theresa Scholand, Marie Schöpping, Nina Sonntag, Jochen Büchs   +8 more
doaj   +1 more source

Optical control of the β2-adrenergic receptor with opto-prop-2: A cis-active azobenzene analog of propranolol

iScience, 2022
Summary: In this study, we synthesized and evaluated new photoswitchable ligands for the beta-adrenergic receptors β1-AR and β2-AR, applying an azologization strategy to the first-generation beta-blocker propranolol. The resulting compounds (Opto-prop-1,
Reggie Bosma, Nicola C. Dijon, Yang Zheng, Hannes Schihada, Niels J. Hauwert, Shuang Shi, Marta Arimont, Rick Riemens, Hans Custers, Andrea van de Stolpe, Henry F. Vischer, Maikel Wijtmans, Nicholas D. Holliday, Diederik W.D. Kuster, Rob Leurs   +14 more
doaj  

Interaction and Mechanism of Probiotics with Gut Flora and Immune Regulation: A Review

Shipin gongye ke-ji, 2022
Probiotics play beneficial roles in improving the host intestinal microecological balance and improving the host health level and health state. It mainly affects the host health by regulating the intestinal microbiota and participating in the immune ...
Manyu TANG, Wanqing WANG, Jingwen QIANG, Wei HUA, Shuang WU, Yali LI, Xin ZHEN, Chungeng LI, Yanling CHENG   +8 more
doaj   +1 more source