Results 121 to 130 of about 1,003,439 (343)
iScience, 2019 Summary: Membraneless organelles (MLOs) are liquid-like subcellular compartments providing spatiotemporal control to biological processes. This study reveals that cellular stress leads to the incorporation of the adaptor protein SINTBAD (TBKBP1) into ...
Vera Vivian Saul +5 more
doaj +1 more source
Searching for a Cure for Cancer [PDF]
, 2009 For Professor Anne Kruchten, cancer is more than a disease as she and her students pursue a research agenda to help improve understanding about how the disease ...
Mileham, Mardi
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Corrigendum: Student-Produced Video of Role-Plays on Topics in Cell Biology and Biochemistry: A Novel Undergraduate Group Work Exercise [PDF]
, 2020 Paul Young
openalex +1 more source
Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science [PDF]
, 2023 J. Robin Harris, Viktor I. Korolchuk
openalex +1 more source
Educating the educators: Incorporating bioinformatics into biological science education in Malaysia [PDF]
, 2012 Bioinformatics can be defined as a fusion of computational and biological sciences. The urgency to process and analyse the deluge of data created by proteomics and genomics studies has caused bioinformatics to gain prominence and importance. However, its
Hussein, Huszalina +3 more
core
Robust persistence and permanence of polynomial and power law dynamical systems
, 2017 A persistent dynamical system in $\mathbb{R}^d_{> 0}$ is one whose solutions have positive lower bounds for large $t$, while a permanent dynamical system in $\mathbb{R}^d_{> 0}$ is one whose solutions have uniform upper and lower bounds for large $t ...
Brunner, James D., Craciun, Gheorghe
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Therapeutic potential of flavonols in the treatment of JCPyV
Microbiology SpectrumJC polyomavirus (JCPyV) is a double-stranded DNA virus that causes progressive multifocal leukoencephalopathy (PML), a demyelinating disease with a high rate of morbidity and mortality. There are limited treatment options for patients diagnosed with PML,
Evan MacLure +7 more
doaj +1 more source