Results 11 to 20 of about 1,003,439 (343)

Applications Of Microspectroscopy, Hyperspectral Chemical Imaging And Fluorescence Microscopy In Chemistry, Biochemistry, Biotechnology, Molecular And Cell Biology [PDF]

open access: diamond, 2011
Chemical imaging is a technique for the simultaneous measurement of spectra (chemical information) and images or pictures (spatial information)^1,2^. The technique is most often applied to either solid or gel samples, and has applications in chemistry ...
Ion C. Băianu
openalex   +3 more sources

Use of biosensors for rapid and sensitive detection of pesticides in food samples for food safety chemical risk assessment

open access: yesEFSA Journal, 2022
The utility of pesticides in the agricultural field is unquestionable, but at the same time pesticide use presents serious hazards to the environment and the human health.
Vasiliki Garefalaki   +3 more
doaj   +1 more source

Exploiting viral sensing mediated by Toll-like receptors to design innovative vaccines

open access: yesnpj Vaccines, 2021
Toll-like receptors (TLRs) are transmembrane proteins belonging to the family of pattern-recognition receptors. They function as sensors of invading pathogens through recognition of pathogen-associated molecular patterns.
Rossella Sartorius   +4 more
doaj   +1 more source

Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles

open access: yesScientific Reports, 2022
Repurposing FDA-approved drugs is an efficient and cost-effective approach in the development of therapeutics for a broad range of diseases. However, prediction of function can be challenging, especially in the brain. We screened a small-molecule library
Sara Tucker Edmister   +7 more
doaj   +1 more source

Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer

open access: yesNature Communications, 2022
The colonic mucus layer is an organized system providing a physical barrier against pathogens and simultaneously harbouring the commensal flora. Here the authors report that transglutaminase 3 activity contributes to homeostasis of the colonic mucus ...
Jack D. A. Sharpen   +8 more
doaj   +1 more source

An 8-cage imaging system for automated analyses of mouse behavior

open access: yesScientific Reports, 2023
The analysis of mouse behavior is used in biomedical research to study brain function in health and disease. Well-established rapid assays allow for high-throughput analyses of behavior but have several drawbacks, including measurements of daytime ...
Thaís Del Rosario Hernández   +4 more
doaj   +1 more source

Adult Hippocampal Neurogenesis in Alzheimer’s Disease: An Overview of Human and Animal Studies with Implications for Therapeutic Perspectives Aimed at Memory Recovery

open access: yesNeural Plasticity, 2022
The mammalian hippocampal dentate gyrus is a niche for adult neurogenesis from neural stem cells. Newborn neurons integrate into existing neuronal networks, where they play a key role in hippocampal functions, including learning and memory. In the ageing
Stefano Farioli-Vecchioli   +2 more
doaj   +1 more source

The untapped potential of plant thin cell layers [PDF]

open access: yes, 2015
Thin cell layers (TCLs), which contain a small number of cells or tissues, are explants excised from different organs (stems, leaves, roots, inflorescences, flowers, cotyledons, hypocotyls/epicotyls, and embryos).
Botero Giraldo   +15 more
core   +1 more source

Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1G93A mice

open access: yesScientific Reports, 2022
miRNAs are necessary for neuromuscular junction (NMJ) health; however, little is known about the proteins required for their activity in this regard.
Dillon Shapiro   +3 more
doaj   +1 more source

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