Results 21 to 30 of about 956,419 (320)
An 8-cage imaging system for automated analyses of mouse behavior
The analysis of mouse behavior is used in biomedical research to study brain function in health and disease. Well-established rapid assays allow for high-throughput analyses of behavior but have several drawbacks, including measurements of daytime ...
Thaís Del Rosario Hernández+4 more
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More than 75% of epithelial ovarian cancer (EOC) patients experience disease recurrence after initial treatment, highlighting our incomplete understanding of how chemoresistant populations evolve over the course of EOC progression post chemotherapy ...
Carolina Mejia Peña+5 more
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This is a problem-based learning case for a medical biochemistry-molecular biology course suitable for first- or second-year medical students. The case is that of a young girl who is diagnosed as a compound heterozygote for Gaucher disease and is treated
Marshall Anderson
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Most of the fascinating phenomena studied in cell biology emerge from interactions among highly organized multimolecular structures embedded into complex and frequently dynamic cellular morphologies.
Margaret E. Johnson+9 more
semanticscholar +1 more source
Peptides as multifunctional players in cancer therapy
Peptides exhibit lower affinity and a shorter half-life in the body than antibodies. Conversely, peptides demonstrate higher efficiency in tissue penetration and cell internalization than antibodies. Regardless of the pros and cons of peptides, they have
Sri Murugan Poongkavithai Vadevoo+7 more
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Give me a SINE: how Selective Inhibitors of Nuclear Export modulate autophagy and aging
Autophagy is a cellular recycling process leading to lysosomal degradation of damaged macromolecules, which can protect cells against aging. The transcription factor EB (TFEB), a major transcriptional regulator of genes involved in autophagy and ...
A.V. Kumar+5 more
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miRNAs are necessary for neuromuscular junction (NMJ) health; however, little is known about the proteins required for their activity in this regard.
Dillon Shapiro+3 more
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Background Bronchopulmonary dysplasia (BPD) is a chronic lung disease in premature infants that may cause long-term lung dysfunction. Accumulating evidence supports the vascular hypothesis of BPD, in which lung endothelial cell dysfunction drives this ...
Jason L. Chang+7 more
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A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
The Piwi-interacting RNA (piRNA) pathway is known to suppress transposable elements in gonadal tissues. Here the authors provide evidence for a functional piRNA pathway in the somatic cells of theDrosophilafat body with roles in metabolism, immunological
Brian C. Jones+6 more
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The biochemical basis of disease [PDF]
Understanding Biochemistry is an essential online resource for post-16 students, teachers and undergraduates, providing up-to-date overviews of key concepts in biochemistry and molecular biosciences.
Ahlqvist+52 more
core +1 more source