Results 51 to 60 of about 85,620 (210)

A PCA3 gene-based transcriptional amplification system targeting primary prostate cancer. [PDF]

, 2015
Targeting specifically primary prostate cancer (PCa) cells for immune therapy, gene therapy or molecular imaging is of high importance. The PCA3 long non-coding RNA is a unique PCa biomarker and oncogene that has been widely studied.
Fradet, Yves, Jain, Pallavi, Neveu, Bertrand, Pouliot, Frédéric, Têtu, Bernard, Wu, Lily   +5 more
core   +2 more sources

Angiogenic Potential of Small Extracellular Vesicles Produced by Stimulated Mesenchymal Stromal Cells Under Hypoxic Conditions

Journal of Extracellular Biology, Volume 5, Issue 1, January 2026.
ABSTRACT Regenerative vascular medicine research has positioned mesenchymal stromal cells (MSCs) as a leading candidate to treat ischemic diseases. Recent studies have highlighted the emerging role of small extracellular vesicles (sEVs) produced by MSCs in their own potential.
Nada Serhal, Bertrand Brassart, Lise Nannan, Sandra Audonnet, Christine Terryn, Gaël Poitevin, Pascale Cornillet‐Lefebvre, Florine Dubuisson, Hélène Peyret, Philippe Nguyen, Claire Tournois   +10 more
wiley   +1 more source

Macromolecules and Enzymes: The Geneva Heritage from Kurt H. Meyer and Edmond H. Fischer

CHIMIA, 2009
On the 26th May 2009, Edmond Fischer, winner with Ed Krebs of the Nobel prize in physiology or medicine in 1992, and his colleague at the time of his research activities at the Ecole de chimie of the University of Geneva, Alfred Piguet, met with
Edmond H. Fischer, Alfred Piguet
doaj   +1 more source

Cell entry mechanism of enzymatic bacterial colicins: Porin recruitment and the thermodynamics of receptor binding [PDF]

, 2005
Binding of enzymatic E colicins to the vitamin B-12 receptor, BtuB, is the first stage in a cascade of events that culminate in the translocation of the cytotoxic nuclease into the Escherichia coli cytoplasm and release of its tightly bound immunity ...
Housden, Nicholas G., James, Richard, Kleanthous, Colin, Loftus, Steven R., Moore, Geoffrey R.   +4 more
core   +3 more sources

High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension

BMC Biotechnology, 2018
Background Dicer is a 219-kDa protein that plays key roles in gene regulation, particularly as the ribonuclease III enzyme responsible for cleaving precursor miRNA substrates.
Jonathan Bouvette, Dursun Nizam Korkut, Aurélien Fouillen, Soumiya Amellah, Antonio Nanci, Yves Durocher, James G. Omichinski, Pascale Legault   +7 more
doaj   +1 more source

Comparison of photosynthesis and antioxidant performance of several Citrus and Fortunella species under natural chilling stress : S08P24 [PDF]

, 2012
Citrus plants originate from southeastern Asia, in a large area with various climates characterized by a broad range of temperatures. Temperature is assumed to be a key factor in Citrus species adaptation and diversification.
Berti, Liliane, Giannettini, Jean, Herbette, Stéphane, Luro, François, Ollitrault, Patrick, Pailly, Olivier, Santini, Jérémie   +6 more
core  

Quantitative Treatments for Explaining the Mechanism and Kinetics of Catalytic Electron Transfers in Murburn Processes, Particularly Involving Heme Enzymes Like (Per)oxidases and P450s

BioMed Research International, Volume 2026, Issue 1, 2026.
The seminal Michaelis–Menten theorization for biological catalysis was based on “transition state” (TS), involving the formation of a topologically complementary substrate (S) and enzyme (E) complex (ES) at the “active site” of the latter. Rudolph Marcus put forth the theory of outer sphere electron transfer (ET) in a “donor–acceptor” TS complex, which
Kelath Murali Manoj, Daniel Andrew Gideon, Philip Moses Samuel, Suhotra Das, Nahit Gencer   +4 more
wiley   +1 more source

Genetic Predisposition to Diabetic Nephropathy: Role of I/D ACE Gene Polymorphism

Journal de la Faculté de Médecine d'Oran, 2022
Introduction - Diabetic nephropathy is the leading cause of chronic kidney disease and the most common and serious complication of diabetes. Its exact pathogenesis is complex and not completely elucidated.
Sabah HANACHI, Karima SIFI, Khalida BOUDAOUD, Salim ZEKRI, Hanane HOUAMEL, Soumia HASSINI, Karima BENEMBAREK   +6 more
doaj  

Correlation between apolipoprotein A-IV and triglyceride concentrations in human sera.

Journal of Lipid Research, 1989
Apolipoprotein A-IV concentration was measured by a newly developed competitive enzyme immunoassay in sera from fasted human subjects (n = 105) whose triglyceride concentrations ranged from 20 to 474 mg/dl (total cholesterol below 260 mg/dl) and in which
L Lagrost, P Gambert, S Meunier, P Morgado, J Desgres, P d'Athis, C Lallemant   +6 more
doaj   +1 more source

DNA recovery from used malaria RDT to detect Plasmodium species and to assess Plasmodium falciparum genetic diversity: a pilot study in Madagascar

Malaria Journal, 2022
Background Rapid diagnostic tests (RDT) are widely used for malaria diagnosis in Madagascar, where Plasmodium falciparum is the predominant species. Molecular diagnosis is essential for malaria surveillance, but requires additional blood samples for DNA ...
Voahangy Hanitriniaina I. Andrianaranjaka, Elisabeth Ravaoarisoa, Tovonahary A. Rakotomanga, Fanomezantsoa Ralinoro, Danielle A. Doll Rakoto, Ranjàna H. Randrianarivo, Victor Jeannoda, Arsène Ratsimbasoa   +7 more
doaj   +1 more source