Results 61 to 70 of about 10,988,700 (173)

Data-Driven Inference Reveals Distinct and Conserved Dynamic Pathways of Tool Use Emergence across Animal Taxa

iScience, 2020
Summary: Tool use is a striking aspect of animal behavior, but it is hard to infer how the capacity for different types of tool use emerged across animal taxa.
Iain G. Johnston, Ellen C. Røyrvik
doaj   +1 more source

ACKR3 in olfactory glia cells shapes the immune defense of the olfactory mucosa

Glia, Volume 72, Issue 6, Page 1183-1200, June 2024.
Main Points Olfactory sustentacular cells express the atypical chemokine receptor ACKR3. ACKR3 cKO increases the expression of immune defense genes in sustentacular cells and Bowman’s glands. ACKR3 cKO leads to leukocyte recruitment to the olfactory mucosa.
André Dietz, Katja Senf, Eva M. Neuhaus
wiley   +1 more source

Structural enzymology studies with the substrate 3S‐hydroxybutanoyl‐CoA: bifunctional MFE1 is a less efficient dehydrogenase than monofunctional HAD

FEBS Open Bio, Volume 14, Issue 4, Page 655-674, April 2024.
Enzyme kinetic studies of rat multifunctional enzyme, type‐1 (RnMFE1) (monomeric, two active sites: ECH, HAD) and human 3S‐hydroxyacyl‐CoA dehydrogenase (HsHAD) (dimeric, one active site: HAD) show that RnMFE1 is a slower dehydrogenase than HsHAD. It is discussed that the different assembly and predicted different flexibility properties of MFE1 (curved
Shruthi Sridhar, Tiila‐Riikka Kiema, Werner Schmitz, Mikael Widersten, Rik K. Wierenga   +4 more
wiley   +1 more source

The journey towards clinical adoption of MALDI‐MS‐based imaging proteomics: from current challenges to future expectations

FEBS Letters, Volume 598, Issue 6, Page 621-634, March 2024.
In recent years, there is increasing evidence to suggest that matrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI‐MSI) technology could offer support in clinical decision‐making processes. Here, we discuss some of the recent technical developments underpinning this progress and outline some of the more promising clinical ...
Isabella Piga, Fulvio Magni, Andrew Smith   +2 more
wiley   +1 more source

Molecular Analysis of Streptomycin Resistance Genes in Clinical Strains of Mycobacterium tuberculosis and Biocomputational Analysis of the MtGidB L101F Variant

, 2021
Globally, tuberculosis (TB) remains a prevalent threat to public health. In 2019, TB affected 10 million people and caused 1.4 million deaths. The major challenge for controlling this infectious disease is the emergence and spread of drug-resistant ...
Rosa E. Mares-Alejandre, Patricia L. A. Muñoz-Muñoz, Marco A. Ramos-Ibarra, Alexei F. Licea-Navarro, Álvaro Rodríguez-García, Johanna Bernáldez-Sarabia, Samuel G. Meléndez-López, Samuel Ruvalcaba-Ruiz, Ricardo A. González-Sánchez   +8 more
core   +1 more source

Endodermal cells use contact inhibition of locomotion to achieve uniform cell dispersal during zebrafish gastrulation

iScience
Summary: The endoderm is one of the three primary germ layers that gives rise to the gastrointestinal and respiratory epithelia and other tissues. Prior to epithelium formation, endodermal cells are highly migratory with only transient interactions among
Jesselynn LaBelle, Tom Wyatt, Jaxson Ramirez, Stephanie Woo   +3 more
doaj   +1 more source

Tissue niches and immunopathology through the lens of spatial tissue profiling techniques

European Journal of Immunology, Volume 54, Issue 2, February 2024.
Spatial tissue profiling techniques identify a large number of proteins and/or genes within tissues, enabling in situ cell type and cell state identification and cell communication analysis. From a spatial immunology perspective, these techniques may reveal the role of distinct tissue niches in modulating local immune responses and directing tissue ...
Anna Pascual‐Reguant, Sandy Kroh, Anja E. Hauser   +2 more
wiley   +1 more source

Biocomputational Immersive Learning

, 2008
Article published in Mathematics Exchange, 5(1), 2008.Biocomputational methods can broadly be viewed as information management systems at the interface of mathematics, statistics, computer science, and molecular biology/genetics. The main objective is to
Bagga, Jay, Begum, Munni, Blakey, Ann
core  

DNA logic programming: From concept to construction

VIEW, Volume 5, Issue 1, February 2024.
DNA logic gates in the application domain of DNA nanostructures play a crucial role in discerning and quantifying the authenticity of events, thereby establishing self‐driven control over event feedback. Building upon this foundation, DNA logic circuits, which integrate multiple independent DNA logic gates, enable autonomous assessment of complex ...
Yi Zhang, Ning Hu, Jiajie Xu, Zhen Wang
wiley   +1 more source

Characterization of multiple lysophosphatidic acid acyltransferases in the plant pathogen Xanthomonas campestris

The FEBS Journal, Volume 291, Issue 4, Page 705-721, February 2024.
The plant pathogen Xanthomonas campestris is characterized by a complex membrane lipid composition with various headgroups and fatty acids (FA). Bacteria incorporate FAs into membrane lipids through a two‐step acylation of glycerol‐3‐phosphate to phosphatidic acid, with PlsC enzymes driving the second acylation.
Georgios Vasilopoulos, Lukas Heflik, Simon Czolkoss, Florian Heinrichs, Julia Kleetz, Cansel Yesilyurt, Dirk Tischler, Philipp Westhoff, Marten Exterkate, Meriyem Aktas, Franz Narberhaus   +10 more
wiley   +1 more source