Results 51 to 60 of about 7,742 (179)

Red‐to‐Near‐Infrared Fluorescence Resonance Energy Transfer Reporters for Dual Imaging Applications

Small Methods, Volume 10, Issue 15, 7 August 2026.
Genetically encoded FRET biosensors reveal dynamic signaling in living cells, but overlapping spectra have limited the simultaneous monitoring of multiple pathways. We introduce a red‐to‐near infrared FRET pair, mRuby2/miRFP670nano3, compatible with existing reporters and enabling dual FLIM‐FRET without bleed‐through.
Van Thi‐Hong Tran, Frans Ek, Hasan Yassine, Rajalaxmi Behera, Vesa P. Hytönen, James R. W. Conway   +5 more
wiley   +1 more source

Matrix-Chain Multiplication Based on Combinatorial Allosteric DNA Strand Displacement

IEEE Access
DNA computing has gained widespread attention for leveraging the unique properties of DNA molecules to perform computational operations. As a fundamental tool for analyzing data and optimizing models, matrix operation plays an important role in intensive
Hengyan Guo, Mingliang Wang, Xuedong Zheng   +2 more
doaj   +1 more source

An unattended image‐processing pipeline for on‐the‐fly quality assessment and 3D exploration in cryo‐EM

Acta Crystallographica Section D, Volume 82, Issue 8, Page 915-939, August 2026.
We present a fully automated, unattended cryo‐EM pipeline that serves as an on‐the‐fly diagnostic tool, enabling rapid data‐quality assessment and informed decision‐making to maximize data‐collection efficiency.Single‐particle analysis (SPA) by cryogenic electron microscopy (cryo‐EM) has become a cornerstone of structural biology; yet, the workflow ...
Daniel Marchán Torres, Pablo Conesa, Alberto Garcia, Mikel Iceta, Ludovic Broche, Marcos Gragera, Romain Linares, Hok Sau Kwong, Francisco Javier Chichón, Olof Svensson, Rocío Arranz, Grégory Effantin, Eaazhisai Kandiah, José María Carazo, Carlos O. S. Sorzano   +14 more
wiley   +1 more source

Starting a synthetic biological intelligence lab from scratch

Patterns
Summary: Recent advances in artificial intelligence (AI) have led to the development and deployment of gigantic models trained on billions of samples.
Md Sayed Tanveer, Dhruvik Patel, Hunter E. Schweiger, Kwaku Dad Abu-Bonsrah, Brad Watmuff, Azin Azadi, Sergey Pryshchep, Karthikeyan Narayanan, Christopher Puleo, Kannathal Natarajan, Mohammed A. Mostajo-Radji, Brett J. Kagan, Ge Wang   +12 more
doaj   +1 more source

Material Strategies for Stimulation and Recording in Neural Biocomputing Platforms

Advanced Electronic Materials
Neural biocomputing is an emerging computing paradigm in which living neural networks serve as substrates for information processing, offering adaptive and energy‐efficient alternatives to conventional silicon‐based architectures.
Sehong Kang, Junggeon Park, Aryaman Joshi, Rakid Haque, Gyu Weon Hwang, Hyunjoon Kong   +5 more
doaj   +1 more source

Exploring thylakoid emergence: evolution of membrane biogenesis and photosystem II assembly in early‐diverging cyanobacteria

New Phytologist, Volume 251, Issue 3, Page 1329-1343, August 2026.
Overview of the results. Phylogenetic analyses of 36 assembly factors of photosystem II (PSII) and 13 proteins involved in membrane dynamics summarized in Siebenaller & Schneider (2023) were performed to investigate the taxonomic distributions and structural differences between the thylakoid‐less Gloeobacterales and the Phycobacteria. Summary Thylakoid
Louise Hambücken, Denis Baurain, Luc Cornet   +2 more
wiley   +1 more source

From simulation to reality: experimental analysis of a quantum entanglement simulation with slime molds (Physarum polycephalum) as bioelectronic components

Frontiers in Soft Matter
This study investigates whether it is possible to simulate quantum entanglement with theoretical memristor models, physical memristors (from Knowm Inc.) and slime molds Physarum polycephalum as bioelectric components.
Markus Schmidt, Günter Seyfried, Uliana Reutina, Zeki Seskir, Eduardo R. Miranda   +4 more
doaj   +1 more source

Deep Consensus, a deep learning-based approach for particle pruning in cryo-electron microscopy

IUCrJ, 2018
Single-particle cryo-electron microscopy (cryo-EM) has recently become a mainstream technique for the structural determination of macromolecules. Typical cryo-EM workflows collect hundreds of thousands of single-particle projections from thousands of ...
Ruben Sanchez-Garcia, Joan Segura, David Maluenda, Jose Maria Carazo, Carlos Oscar S. Sorzano   +4 more
doaj   +1 more source

Embedding-Based Alignments Capture Structural and Sequence Domains of Distantly Related Multifunctional Human Proteins

Computation
Protein embedding is a protein representation that carries along the information derived from filtering large volumes of sequences stored in large archives.
Gabriele Vazzana, Matteo Manfredi, Castrense Savojardo, Pier Luigi Martelli, Rita Casadio   +4 more
doaj   +1 more source

Biocomputing system of living cells [PDF]

Computer Science Journal of Moldova, 2002
The aim of this paper1 is to show that the process of gene transcription can be represented as a finite automaton illustrating the processing of input/output signals in living cells at DNA level.
Aurelia Profir
doaj