Results 21 to 30 of about 620 (141)

First Plant Cell Atlas symposium report

Plant Direct, 2022
The Plant Cell Atlas (PCA) community hosted a virtual symposium on December 9 and 10, 2021 on single cell and spatial omics technologies. The conference gathered almost 500 academic, industry, and government leaders to identify the needs and directions ...
Selena L. Rice, Elena Lazarus, Christopher Anderton, Kenneth Birnbaum, Jennifer Brophy, Benjamin Cole, Diane Dickel, David Ehrhardt, Noah Fahlgren, Margaret Frank, Elizabeth Haswell, Shao‐shan Carol Huang, Samuel Leiboff, Marc Libault, Marisa S. Otegui, Nicholas Provart, R. Glen Uhrig, Seung Y. Rhee, The Plant Cell Atlas Consortium   +18 more
doaj   +2 more sources

BI‐LAVA: Biocuration With Hierarchical Image Labelling Through Active Learning and Visual Analytics

Computer Graphics Forum, Volume 44, Issue 1, February 2025.
BI‐LAVA is an innovative labeling system designed for the hierarchical annotation of image modalities in biocuration. By integrating visual analytics with machine learning techniques, BI‐LAVA facilitates the understanding of biomedical datasets for users with limited expertise.
Juan Trelles, Andrew Wentzel, William Berrios, Hagit Shatkay, G. Elisabeta Marai   +4 more
wiley   +2 more sources

Diverse Taxonomies for Diverse Chemistries: Enhanced Representation of Natural Product Metabolism in UniProtKB

Metabolites, 2021
The UniProt Knowledgebase UniProtKB is a comprehensive, high-quality, and freely accessible resource of protein sequences and functional annotation that covers genomes and proteomes from tens of thousands of taxa, including a broad range of plants and ...
Marc Feuermann, Emmanuel Boutet, Anne Morgat, Kristian B. Axelsen, Parit Bansal, Jerven Bolleman, Edouard de Castro, Elisabeth Coudert, Elisabeth Gasteiger, Sébastien Géhant, Damien Lieberherr, Thierry Lombardot, Teresa B. Neto, Ivo Pedruzzi, Sylvain Poux, Monica Pozzato, Nicole Redaschi, Alan Bridge, on behalf of the UniProt Consortium   +18 more
doaj   +1 more source

ECO-CollecTF: A Corpus of Annotated Evidence-Based Assertions in Biomedical Manuscripts

Frontiers in Research Metrics and Analytics, 2021
Analysis of high-throughput experiments in the life sciences frequently relies upon standardized information about genes, gene products, and other biological entities.
Elizabeth T. Hobbs, Stephen M. Goralski, Ashley Mitchell, Andrew Simpson, Dorjan Leka, Emmanuel Kotey, Matt Sekira, James B. Munro, Suvarna Nadendla, Rebecca Jackson, Aitor Gonzalez-Aguirre, Martin Krallinger, Martin Krallinger, Michelle Giglio, Ivan Erill   +14 more
doaj   +1 more source

Expert Panel Curation of 113 Primary Mitochondrial Disease Genes for the Leigh Syndrome Spectrum

Annals of Neurology, Volume 94, Issue 4, Page 696-712, October 2023., 2023
Objective Primary mitochondrial diseases (PMDs) are heterogeneous disorders caused by inherited mitochondrial dysfunction. Classically defined neuropathologically as subacute necrotizing encephalomyelopathy, Leigh syndrome spectrum (LSS) is the most frequent manifestation of PMD in children, but may also present in adults.
Elizabeth M. McCormick, Kierstin Keller, Julie P. Taylor, Alison J. Coffey, Lishuang Shen, Danuta Krotoski, Brian Harding, NICHD ClinGen U24 Mitochondrial Disease Gene Curation Expert Panel, César Augusto Pinheiro Ferreira Alves, Anna Ardissone, Renkui Bai, Isabella Peixoto de Barcelos, Enrico Bertini, Krista Bluske, John Christodoulou, Amanda R. Clause, William C. Copeland, George A. Diaz, Daria Diodato, Matthew C. Dulik, Greg Enns, Annette Feigenbaum, Carl Fratter, Daniele Ghezzi, Amy Goldstein, Andrea Gropman, Richard Haas, Amel Karaa, Mary Kay Koenig, Berrin Monteleone, Sumit Parikh, Belen Perez Duenas, Revathi Rajkumar, Ann Saada, Russell P. Saneto, Kate Sergeant, John Shoffner, Conrad Smith, Christine Stanley, Isabelle Thiffault, David Thorburn, Melissa Walker, Douglas Wallace, Lee‐Jun Wong, Xiaowu Gai, Marni J. Falk, Zarazuela Zolkipli‐Cunningham, Shamima Rahman   +47 more
wiley   +1 more source

GOing Forward With the Cardiac Conduction System Using Gene Ontology

Frontiers in Genetics, 2022
The cardiac conduction system (CCS) comprises critical components responsible for the initiation, propagation, and coordination of the action potential. Aberrant CCS development can cause conduction abnormalities, including sick sinus syndrome, accessory
Kan Yan Chloe Li, Kan Yan Chloe Li, Andrew C Cook, Ruth C Lovering   +3 more
doaj   +1 more source

Announcing the launch of Protein Data Bank China as an Associate Member of the Worldwide Protein Data Bank Partnership

Acta Crystallographica Section D, Volume 79, Issue 9, Page 792-795, September 2023., 2023
The formal launch of Protein Data Bank China (PDBc) is announced, and the history of the wwPDB, recently established mechanisms for adding new wwPDB data centers and the processes developed to bring PDBc into the partnership are described.The Protein Data Bank (PDB) is the single global archive of atomic‐level, three‐dimensional structures of ...
Wenqing Xu, Sameer Velankar, Ardan Patwardhan, Jeffrey C. Hoch, Stephen K. Burley, Genji Kurisu   +5 more
wiley   +1 more source

Term Matrix: a novel Gene Ontology annotation quality control system based on ontology term co-annotation patterns [PDF]

Open Biology, 2020
Biological processes are accomplished by the coordinated action of gene products. Gene products often participate in multiple processes, and can therefore be annotated to multiple Gene Ontology (GO) terms.
Valerie Wood, Seth Carbon, Midori A. Harris, Antonia Lock, Stacia R. Engel, David P. Hill, Kimberly Van Auken, Helen Attrill, Marc Feuermann, Pascale Gaudet, Ruth C. Lovering, Sylvain Poux, Kim M. Rutherford, Christopher J. Mungall   +13 more
doaj   +1 more source

Evolution and adoption of contributor role ontologies and taxonomies

Learned Publishing, Volume 36, Issue 2, Page 275-284, April 2023., 2023
Abstract Contributor Role Ontologies and Taxonomies (CROTs) are standard vocabularies to describe individual contributions to a scholarly project or research output. Contributor Roles Taxonomy (CRediT) is one of the most widely used CROTs, and has been adopted by numerous journals to describe author's contributions, and recently formalized as a ANSI ...
Mohammad Hosseini, Julien Colomb, Alex O. Holcombe, Barbara Kern, Nicole A. Vasilevsky, Kristi L. Holmes   +5 more
wiley   +1 more source

RCSB Protein Data bank: Tools for visualizing and understanding biological macromolecules in 3D

Protein Science, Volume 31, Issue 12, December 2022., 2022
Abstract Now in its 52nd year of continuous operations, the Protein Data Bank (PDB) is the premiere open‐access global archive housing three‐dimensional (3D) biomolecular structure data. It is jointly managed by the Worldwide Protein Data Bank (wwPDB) partnership.
Stephen K. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Henry Chao, Li Chen, Paul A. Craig, Gregg V. Crichlow, Kenneth Dalenberg, Jose M. Duarte, Shuchismita Dutta, Maryam Fayazi, Zukang Feng, Justin W. Flatt, Sai J. Ganesan, Sutapa Ghosh, David S. Goodsell, Rachel Kramer Green, Vladimir Guranovic, Jeremy Henry, Brian P. Hudson, Igor Khokhriakov, Catherine L. Lawson, Yuhe Liang, Robert Lowe, Ezra Peisach, Irina Persikova, Dennis W. Piehl, Yana Rose, Andrej Sali, Joan Segura, Monica Sekharan, Chenghua Shao, Brinda Vallat, Maria Voigt, Benjamin Webb, John D. Westbrook, Shamara Whetstone, Jasmine Y. Young, Arthur Zalevsky, Christine Zardecki   +40 more
wiley   +1 more source