Results 21 to 30 of about 1,082 (162)

Evolution and adoption of contributor role ontologies and taxonomies

Learned Publishing, Volume 36, Issue 2, Page 275-284, April 2023., 2023
Abstract Contributor Role Ontologies and Taxonomies (CROTs) are standard vocabularies to describe individual contributions to a scholarly project or research output. Contributor Roles Taxonomy (CRediT) is one of the most widely used CROTs, and has been adopted by numerous journals to describe author's contributions, and recently formalized as a ANSI ...
Mohammad Hosseini, Julien Colomb, Alex O. Holcombe, Barbara Kern, Nicole A. Vasilevsky, Kristi L. Holmes   +5 more
wiley   +1 more source

RCSB Protein Data bank: Tools for visualizing and understanding biological macromolecules in 3D

Protein Science, Volume 31, Issue 12, December 2022., 2022
Abstract Now in its 52nd year of continuous operations, the Protein Data Bank (PDB) is the premiere open‐access global archive housing three‐dimensional (3D) biomolecular structure data. It is jointly managed by the Worldwide Protein Data Bank (wwPDB) partnership.
Stephen K. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Henry Chao, Li Chen, Paul A. Craig, Gregg V. Crichlow, Kenneth Dalenberg, Jose M. Duarte, Shuchismita Dutta, Maryam Fayazi, Zukang Feng, Justin W. Flatt, Sai J. Ganesan, Sutapa Ghosh, David S. Goodsell, Rachel Kramer Green, Vladimir Guranovic, Jeremy Henry, Brian P. Hudson, Igor Khokhriakov, Catherine L. Lawson, Yuhe Liang, Robert Lowe, Ezra Peisach, Irina Persikova, Dennis W. Piehl, Yana Rose, Andrej Sali, Joan Segura, Monica Sekharan, Chenghua Shao, Brinda Vallat, Maria Voigt, Benjamin Webb, John D. Westbrook, Shamara Whetstone, Jasmine Y. Young, Arthur Zalevsky, Christine Zardecki   +40 more
wiley   +1 more source

Exploring Manually Curated Annotations of Intrinsically Disordered Proteins with DisProt

Current Protocols, Volume 2, Issue 7, July 2022., 2022
Abstract DisProt is the major repository of manually curated data for intrinsically disordered proteins collected from the literature. Although lacking a stable three‐dimensional structure under physiological conditions, intrinsically disordered proteins carry out a plethora of biological functions, some of them directly arising from their flexible ...
Federica Quaglia, András Hatos, Edoardo Salladini, Damiano Piovesan, Silvio C. E. Tosatto   +4 more
wiley   +1 more source

What is biocuration?

, 2023
Introduction to ...
Schriml, Lynn, Sánchez-Beato Johnson, Claudia   +1 more
openaire   +1 more source

Crowdsourcing biocuration: The Community Assessment of Community Annotation with Ontologies (CACAO).

PLoS Computational Biology, 2021
Experimental data about gene functions curated from the primary literature have enormous value for research scientists in understanding biology. Using the Gene Ontology (GO), manual curation by experts has provided an important resource for studying gene
Jolene Ramsey, Brenley McIntosh, Daniel Renfro, Suzanne A Aleksander, Sandra LaBonte, Curtis Ross, Adrienne E Zweifel, Nathan Liles, Shabnam Farrar, Jason J Gill, Ivan Erill, Sarah Ades, Tanya Z Berardini, Jennifer A Bennett, Siobhan Brady, Robert Britton, Seth Carbon, Steven M Caruso, Dave Clements, Ritu Dalia, Meredith Defelice, Erin L Doyle, Iddo Friedberg, Susan M R Gurney, Lee Hughes, Allison Johnson, Jason M Kowalski, Donghui Li, Ruth C Lovering, Tamara L Mans, Fiona McCarthy, Sean D Moore, Rebecca Murphy, Timothy D Paustian, Sarah Perdue, Celeste N Peterson, Birgit M Prüß, Margaret S Saha, Robert R Sheehy, John T Tansey, Louise Temple, Alexander William Thorman, Saul Trevino, Amy Cheng Vollmer, Virginia Walbot, Joanne Willey, Deborah A Siegele, James C Hu   +47 more
doaj   +2 more sources

SARS‐CoV‐2 variants preferentially emerge at intrinsically disordered protein sites helping immune evasion

The FEBS Journal, Volume 289, Issue 14, Page 4240-4250, July 2022., 2022
Intrinsically disordered regions (IDRs) are abundant in the SARS‐CoV‐2 spike glycoprotein S1 subunit and nucleoprotein. Mutations occurring in the 13 main variants, including Omicron, correlate with these IDRs and play a role in immune evasion. Moreover, IDRs in the major antigenic site of the spike glycoprotein suggest a role of intrinsic disorder in ...
Federica Quaglia, Edoardo Salladini, Marco Carraro, Giovanni Minervini, Silvio C.E. Tosatto, Philippe Le Mercier   +5 more
wiley   +1 more source

Studying Biocuration Workflows [PDF]

Nature Precedings, 2009
AbstractAs the first phase of a knowledge engineering study of biocuration workflows, we performed a preliminary task-modeling exercise on seven separate bioinformatics systems. This involved constructing UML activity diagrams from detailed interviews with curators in order to understand the organization of the process the biocurators used to populate ...
Gully Burns, Gully Burns, Martin Krallinger, Kevin Cohen, Cathy Wu, Lynette Hirschman   +5 more
openaire   +3 more sources

Inside FlyBase: Biocuration as a career [PDF]

Fly, 2009
As research in the biological sciences continues to advance at a rapid pace, it is increasingly important that the data be captured, standardized, organized and made accessible to the scientific community. This is the job of a biocurator. Here we describe the process of biocuration from our perspective as FlyBase curators.
Susan, St Pierre, Peter, McQuilton
openaire   +2 more sources

Text mining for identification of biological entities related to antibiotic resistant organisms [PDF]

PeerJ, 2022
Antimicrobial resistance is a significant public health problem worldwide. In recent years, the scientific community has been intensifying efforts to combat this problem; many experiments have been developed, and many articles are published in this area.
Kelle Fortunato Costa, Fabrício Almeida Araújo, Jefferson Morais, Carlos Renato Lisboa Frances, Rommel T. J. Ramos   +4 more
doaj   +2 more sources

Plasma proteins, cognitive decline, and 20‐year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies

Alzheimer's &Dementia, Volume 18, Issue 4, Page 612-624, April 2022., 2022
Abstract Introduction Plasma proteins affect biological processes and are common drug targets but their role in the development of Alzheimer's disease and related dementias remains unclear. We examined associations between 4953 plasma proteins and cognitive decline and risk of dementia in two cohort studies with 20‐year follow‐ups.
Joni V. Lindbohm, Nina Mars, Keenan A. Walker, Archana Singh‐Manoux, Gill Livingston, Eric J. Brunner, Pyry N. Sipilä, Kalle Saksela, Jane E. Ferrie, Ruth C. Lovering, Stephen A. Williams, Aroon D. Hingorani, Rebecca F. Gottesman, Henrik Zetterberg, Mika Kivimäki   +14 more
wiley   +1 more source