Results 21 to 30 of about 1,399 (186)

BI‐LAVA: Biocuration With Hierarchical Image Labelling Through Active Learning and Visual Analytics

Computer Graphics Forum, Volume 44, Issue 1, February 2025.
BI‐LAVA is an innovative labeling system designed for the hierarchical annotation of image modalities in biocuration. By integrating visual analytics with machine learning techniques, BI‐LAVA facilitates the understanding of biomedical datasets for users with limited expertise.
Juan Trelles, Andrew Wentzel, William Berrios, Hagit Shatkay, G. Elisabeta Marai   +4 more
wiley   +2 more sources

Evolution and adoption of contributor role ontologies and taxonomies

Learned Publishing, Volume 36, Issue 2, Page 275-284, April 2023., 2023
Abstract Contributor Role Ontologies and Taxonomies (CROTs) are standard vocabularies to describe individual contributions to a scholarly project or research output. Contributor Roles Taxonomy (CRediT) is one of the most widely used CROTs, and has been adopted by numerous journals to describe author's contributions, and recently formalized as a ANSI ...
Mohammad Hosseini, Julien Colomb, Alex O. Holcombe, Barbara Kern, Nicole A. Vasilevsky, Kristi L. Holmes   +5 more
wiley   +1 more source

Diverse Taxonomies for Diverse Chemistries: Enhanced Representation of Natural Product Metabolism in UniProtKB

Metabolites, 2021
The UniProt Knowledgebase UniProtKB is a comprehensive, high-quality, and freely accessible resource of protein sequences and functional annotation that covers genomes and proteomes from tens of thousands of taxa, including a broad range of plants and ...
Marc Feuermann, Emmanuel Boutet, Anne Morgat, Kristian B. Axelsen, Parit Bansal, Jerven Bolleman, Edouard de Castro, Elisabeth Coudert, Elisabeth Gasteiger, Sébastien Géhant, Damien Lieberherr, Thierry Lombardot, Teresa B. Neto, Ivo Pedruzzi, Sylvain Poux, Monica Pozzato, Nicole Redaschi, Alan Bridge, on behalf of the UniProt Consortium   +18 more
doaj   +1 more source

Term Matrix: a novel Gene Ontology annotation quality control system based on ontology term co-annotation patterns [PDF]

Open Biology, 2020
Biological processes are accomplished by the coordinated action of gene products. Gene products often participate in multiple processes, and can therefore be annotated to multiple Gene Ontology (GO) terms.
Valerie Wood, Seth Carbon, Midori A. Harris, Antonia Lock, Stacia R. Engel, David P. Hill, Kimberly Van Auken, Helen Attrill, Marc Feuermann, Pascale Gaudet, Ruth C. Lovering, Sylvain Poux, Kim M. Rutherford, Christopher J. Mungall   +13 more
doaj   +1 more source

RCSB Protein Data bank: Tools for visualizing and understanding biological macromolecules in 3D

Protein Science, Volume 31, Issue 12, December 2022., 2022
Abstract Now in its 52nd year of continuous operations, the Protein Data Bank (PDB) is the premiere open‐access global archive housing three‐dimensional (3D) biomolecular structure data. It is jointly managed by the Worldwide Protein Data Bank (wwPDB) partnership.
Stephen K. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Henry Chao, Li Chen, Paul A. Craig, Gregg V. Crichlow, Kenneth Dalenberg, Jose M. Duarte, Shuchismita Dutta, Maryam Fayazi, Zukang Feng, Justin W. Flatt, Sai J. Ganesan, Sutapa Ghosh, David S. Goodsell, Rachel Kramer Green, Vladimir Guranovic, Jeremy Henry, Brian P. Hudson, Igor Khokhriakov, Catherine L. Lawson, Yuhe Liang, Robert Lowe, Ezra Peisach, Irina Persikova, Dennis W. Piehl, Yana Rose, Andrej Sali, Joan Segura, Monica Sekharan, Chenghua Shao, Brinda Vallat, Maria Voigt, Benjamin Webb, John D. Westbrook, Shamara Whetstone, Jasmine Y. Young, Arthur Zalevsky, Christine Zardecki   +40 more
wiley   +1 more source

Biocuration 2023 Conference Booklet

, 2023
A description of organizers, sponsors, speakers, and the schedule of the Biocuration 2023 ...
Hoyt, Charles Tapley
core   +2 more sources

Exploring Manually Curated Annotations of Intrinsically Disordered Proteins with DisProt

Current Protocols, Volume 2, Issue 7, July 2022., 2022
Abstract DisProt is the major repository of manually curated data for intrinsically disordered proteins collected from the literature. Although lacking a stable three‐dimensional structure under physiological conditions, intrinsically disordered proteins carry out a plethora of biological functions, some of them directly arising from their flexible ...
Federica Quaglia, András Hatos, Edoardo Salladini, Damiano Piovesan, Silvio C. E. Tosatto   +4 more
wiley   +1 more source

ECO-CollecTF: A Corpus of Annotated Evidence-Based Assertions in Biomedical Manuscripts

Frontiers in Research Metrics and Analytics, 2021
Analysis of high-throughput experiments in the life sciences frequently relies upon standardized information about genes, gene products, and other biological entities.
Elizabeth T. Hobbs, Stephen M. Goralski, Ashley Mitchell, Andrew Simpson, Dorjan Leka, Emmanuel Kotey, Matt Sekira, James B. Munro, Suvarna Nadendla, Rebecca Jackson, Aitor Gonzalez-Aguirre, Martin Krallinger, Martin Krallinger, Michelle Giglio, Ivan Erill   +14 more
doaj   +1 more source

SARS‐CoV‐2 variants preferentially emerge at intrinsically disordered protein sites helping immune evasion

The FEBS Journal, Volume 289, Issue 14, Page 4240-4250, July 2022., 2022
Intrinsically disordered regions (IDRs) are abundant in the SARS‐CoV‐2 spike glycoprotein S1 subunit and nucleoprotein. Mutations occurring in the 13 main variants, including Omicron, correlate with these IDRs and play a role in immune evasion. Moreover, IDRs in the major antigenic site of the spike glycoprotein suggest a role of intrinsic disorder in ...
Federica Quaglia, Edoardo Salladini, Marco Carraro, Giovanni Minervini, Silvio C.E. Tosatto, Philippe Le Mercier   +5 more
wiley   +1 more source

GOing Forward With the Cardiac Conduction System Using Gene Ontology

Frontiers in Genetics, 2022
The cardiac conduction system (CCS) comprises critical components responsible for the initiation, propagation, and coordination of the action potential. Aberrant CCS development can cause conduction abnormalities, including sick sinus syndrome, accessory
Kan Yan Chloe Li, Kan Yan Chloe Li, Andrew C Cook, Ruth C Lovering   +3 more
doaj   +1 more source