Results 31 to 40 of about 620 (141)
Exploring Manually Curated Annotations of Intrinsically Disordered Proteins with DisProt
Current Protocols, Volume 2, Issue 7, July 2022., 2022 Abstract DisProt is the major repository of manually curated data for intrinsically disordered proteins collected from the literature. Although lacking a stable three‐dimensional structure under physiological conditions, intrinsically disordered proteins carry out a plethora of biological functions, some of them directly arising from their flexible ...
Federica Quaglia +4 more
wiley +1 more source
Biocuration 2023 Conference Booklet
, 2023 A description of organizers, sponsors, speakers, and the schedule of the Biocuration 2023 ...
Hoyt, Charles Tapley
core +2 more sources
The FEBS Journal, Volume 289, Issue 14, Page 4240-4250, July 2022., 2022 Intrinsically disordered regions (IDRs) are abundant in the SARS‐CoV‐2 spike glycoprotein S1 subunit and nucleoprotein. Mutations occurring in the 13 main variants, including Omicron, correlate with these IDRs and play a role in immune evasion. Moreover, IDRs in the major antigenic site of the spike glycoprotein suggest a role of intrinsic disorder in ...
Federica Quaglia +5 more
wiley +1 more source
Alzheimer's &Dementia, Volume 18, Issue 4, Page 612-624, April 2022., 2022 Abstract Introduction Plasma proteins affect biological processes and are common drug targets but their role in the development of Alzheimer's disease and related dementias remains unclear. We examined associations between 4953 plasma proteins and cognitive decline and risk of dementia in two cohort studies with 20‐year follow‐ups.
Joni V. Lindbohm +14 more
wiley +1 more source
John D. Westbrook Jr (1957–2021)
Acta Crystallographica Section D, Volume 77, Issue 11, Page 1475-1476, November 2021., 2021 John Westbrook is remembered.John Westbrook is remembered.
Christine Zardecki, Stephen K. Burley
wiley +1 more source
An Evidence‐Based Framework for Evaluating Pharmacogenomics Knowledge for Personalized Medicine
Clinical Pharmacology &Therapeutics, Volume 110, Issue 3, Page 563-572, September 2021., 2021 Clinical annotations are one of the most popular resources available on the Pharmacogenomics Knowledgebase (PharmGKB). Each clinical annotation summarizes the association between variant‐drug pairs, shows relevant findings from the curated literature, and is assigned a level of evidence (LOE) to indicate the strength of support for that association ...
Michelle Whirl‐Carrillo +6 more
wiley +1 more source
APICURON: a database to credit and acknowledge the work of biocurators [PDF]
Database, 2021 Abstract APICURON is an open and freely accessible resource that tracks and credits the work of biocurators across multiple participating knowledgebases. Biocuration is essential to extract knowledge from research data and make it available in a structured and standardized way to the scientific community.
Hatos A. +3 more
openaire +4 more sources
Current Protocols, Volume 1, Issue 7, July 2021., 2021 Abstract The Protein Ensemble Database (PED; https://proteinensemble.org/) is the major repository of conformational ensembles of intrinsically disordered proteins (IDPs). Conformational ensembles of IDPs are primarily provided by their authors or occasionally collected from literature, and are subsequently deposited in PED along with the corresponding
Federica Quaglia +5 more
wiley +1 more source
International Society for Biocuration 2021 Survey results
, 2021 The ISB Equity, Diversity, and Inclusion Subcommittee surveyed members and non-members of the International Society for Biocuration to better understand the community and identify ways in which the ISB could better serve our community.
International Society for Biocuration Equity, Diversity, and Inclusion Committee +1 more
core +1 more source