Results 31 to 40 of about 1,399 (186)
Alzheimer's &Dementia, Volume 18, Issue 4, Page 612-624, April 2022., 2022 Abstract Introduction Plasma proteins affect biological processes and are common drug targets but their role in the development of Alzheimer's disease and related dementias remains unclear. We examined associations between 4953 plasma proteins and cognitive decline and risk of dementia in two cohort studies with 20‐year follow‐ups.
Joni V. Lindbohm +14 more
wiley +1 more source
Inside FlyBase: Biocuration as a career [PDF]
Fly, 2009 As research in the biological sciences continues to advance at a rapid pace, it is increasingly important that the data be captured, standardized, organized and made accessible to the scientific community. This is the job of a biocurator. Here we describe the process of biocuration from our perspective as FlyBase curators.
Susan, St Pierre, Peter, McQuilton
openaire +2 more sources
Studying Biocuration Workflows [PDF]
Nature Precedings, 2009 AbstractAs the first phase of a knowledge engineering study of biocuration workflows, we performed a preliminary task-modeling exercise on seven separate bioinformatics systems. This involved constructing UML activity diagrams from detailed interviews with curators in order to understand the organization of the process the biocurators used to populate ...
Gully Burns +5 more
openaire +3 more sources
John D. Westbrook Jr (1957–2021)
Acta Crystallographica Section D, Volume 77, Issue 11, Page 1475-1476, November 2021., 2021 John Westbrook is remembered.John Westbrook is remembered.
Christine Zardecki, Stephen K. Burley
wiley +1 more source
Text mining for identification of biological entities related to antibiotic resistant organisms [PDF]
PeerJ, 2022 Antimicrobial resistance is a significant public health problem worldwide. In recent years, the scientific community has been intensifying efforts to combat this problem; many experiments have been developed, and many articles are published in this area.
Kelle Fortunato Costa +4 more
doaj +2 more sources
An Evidence‐Based Framework for Evaluating Pharmacogenomics Knowledge for Personalized Medicine
Clinical Pharmacology &Therapeutics, Volume 110, Issue 3, Page 563-572, September 2021., 2021 Clinical annotations are one of the most popular resources available on the Pharmacogenomics Knowledgebase (PharmGKB). Each clinical annotation summarizes the association between variant‐drug pairs, shows relevant findings from the curated literature, and is assigned a level of evidence (LOE) to indicate the strength of support for that association ...
Michelle Whirl‐Carrillo +6 more
wiley +1 more source
Current Protocols, Volume 1, Issue 7, July 2021., 2021 Abstract The Protein Ensemble Database (PED; https://proteinensemble.org/) is the major repository of conformational ensembles of intrinsically disordered proteins (IDPs). Conformational ensembles of IDPs are primarily provided by their authors or occasionally collected from literature, and are subsequently deposited in PED along with the corresponding
Federica Quaglia +5 more
wiley +1 more source
International Society for Biocuration 2021 Survey results
, 2021 The ISB Equity, Diversity, and Inclusion Subcommittee surveyed members and non-members of the International Society for Biocuration to better understand the community and identify ways in which the ISB could better serve our community.
International Society for Biocuration Equity, Diversity, and Inclusion Committee +1 more
core +1 more source
Leveraging generative AI to assist biocuration of medical actions for rare disease. [PDF]
Bioinform AdvMotivation Structured representations of clinical data can support computational analysis of individuals and cohorts, and ontologies representing disease entities and phenotypic abnormalities are now commonly used for translational research.
Niyonkuru E +14 more
europepmc +4 more sources