Results 21 to 30 of about 63,325 (247)
Drug Design, Development and Therapy, 2022 Chen J, Jiang H, Wu Y, Li Y, Gao Y. Drug Des Devel Ther. 2015;9:2265–2275. The Editor and Publisher of Drug Design, Development and Therapy wish to retract the published article.
Chen J, Jiang H, Wu Y, Li Y, Gao Y
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Molecular Therapy: Methods & Clinical DevelopmentInduced pluripotent stem cells (iPSCs) have substantial transformative potential in regenerative medicine, enabling tissue repair and restoration.
Miyu Nakayama +5 more
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Molecules, 2020 Intranasal (i.n.) administration became an alternative strategy to bypass the blood–brain barrier and improve drug bioavailability in the brain. The main goal of this work was to preliminarily study the biodistribution of mixed amphiphilic mucoadhesive ...
Inbar Schlachet +2 more
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Biodistribution of P-selectin targeted microbubbles [PDF]
Journal of Drug Targeting, 2014 To evaluate binding of P-selectin targeted microbubbles (MB) in tumor vasculature; a whole-body imaging and biodistribution study was performed in a tumor bearing mouse model.Antibodies were radiolabeled with Tc-99 m using the HYNIC method. Tc-99 m labeled anti-P-selectin antibodies were avidin-bound to lipid-shelled, perfluorocarbon gas-filled MB and ...
Jason M, Warram +9 more
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Safety Evaluations of Rapamycin Perfluorocarbon Nanoparticles in Ovarian Tumor-Bearing Mice
NanomaterialsNanomedicine holds great potential for revolutionizing medical treatment. Ongoing research and advancements in nanotechnology are continuously expanding the possibilities, promising significant advancements in healthcare.
Qingyu Zhou +13 more
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Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles
Pharmaceutics, 2020 Fluorescent dye labeling is a common strategy to analyze the fate of administered nanoparticles in living organisms. However, to which extent the labeling processes can alter the original nanoparticle biodistribution has been so far neglected.
Patricia Álamo +14 more
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Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model
Frontiers in Bioengineering and BiotechnologyIntroductionTo investigate the metabolism and distribution of iPSC‐MSCs in the joint cavity of rats with knee osteoarthritis (KOA).MethodsThe iPSC‐MSCs labeled with the Antares2 luciferase gene were injected into the knee joints of rats, and then the ...
Xiaoyang Yuan +13 more
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Radioactive Labeling of Milk-Derived Exosomes with 99mTc and In Vivo Tracking by SPECT Imaging
Nanomaterials, 2020 Over the last decade, exosomes from diverse biological sources have been proposed as new natural platforms in drug delivery. Translation of these nanometric tools to clinical practice requires deep knowledge of their pharmacokinetic properties and ...
María Isabel González +3 more
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Biodistribution of mild analgesics. [PDF]
British Journal of Clinical Pharmacology, 1980 1 Macro‐autoradiographic methods were used to assess the biodistribution of [3H]‐, or [14C]‐acidic (aspirin, indomethacin, phenylbutazone) and non‐acidic (antipyrine, aminopyrine, paracetamol) mild analgesics in rats with carrageenan‐induced inflammation.
K, Brune, K D, Rainsford, A, Schweitzer
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AntibioticsBackground: The genetic modification of mesenchymal stromal/stem cells (MSCs) to express antimicrobial peptides may provide a promising strategy for developing advanced cell-based therapies for bacterial infections, including those caused or complicated ...
Vagif Ali oglu Gasanov +8 more
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