Results 11 to 20 of about 97,326 (260)

The Development and Evaluation of Novel Reagents for Pre-Targeted Radioimmunotherapy [PDF]

open access: yes, 2004
PhDIn a pretargeting radioimmunotherapy system, monoclonal antibodies (MAbs) derivatised with a high affinity streptavidin receptor are used in a localisation step.
Hainsworth, James Edward Scott
core   +2 more sources

Visualization of cardiac uptake of bone marrow mesenchymal stem cell‐derived extracellular vesicles after intramyocardial or intravenous injection in murine myocardial infarction

open access: yesPhysiological Reports, 2023
In animal models, human bone marrow mesenchymal stem cell‐derived extracellular vesicles (MSC‐EV) have been found to have beneficial effects in cardiovascular disease, but only when administered via intramyocardial injection.
Cynthia M. Xu   +5 more
doaj   +1 more source

Assessment of the biocompatibility and biodistribution of fluorescent oleic acid capped ZnSe/CdS/ core shell quantum dots after intravenous injection in Balb/c mice [PDF]

open access: yesBioImpacts
Introduction: Quantum dots (QDs) are semiconductor nanocrystals with inherent fluorescence having several advantages over traditional fluorescent probes including their small size (5–10 nm), tunable excitation and emission spectra, ease of surface ...
Aakriti Tyagi   +4 more
doaj   +1 more source

The Impact of Polymer Size and Cleavability on the Intravenous Pharmacokinetics of PEG-Based Hyperbranched Polymers in Rats

open access: yesNanomaterials, 2020
A better understanding of the impact of molecular size and linkers is important for PEG-based hyperbranched polymers (HBPs) intended as tailored drug delivery vehicles.
Nirmal Marasini   +8 more
doaj   +1 more source

Multiphysics pharmacokinetic model for targeted nanoparticles

open access: yesFrontiers in Medical Technology, 2022
Nanoparticles (NP) are being increasingly explored as vehicles for targeted drug delivery because they can overcome free therapeutic limitations by drug encapsulation, thereby increasing solubility and transport across cell membranes.
Emma M. Glass   +7 more
doaj   +1 more source

Optimization in Chemical Modification of Single-Stranded siRNA Encapsulated by Neutral Cytidinyl/Cationic Lipids

open access: yesFrontiers in Chemistry, 2022
Single-stranded siRNA (ss-siRNA) refers to the antisense strand of siRNA, which plays the role of gene silencing. Since single-stranded RNA is unstable, the present study employed a homemade neutral cytidinyl/cationic lipid delivery system and chemical ...
Zheng Li   +5 more
doaj   +1 more source

Exosomes: Biological Pharmaceutical Nanovectors for Theranostics

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Exosomes are natural cell-derived nanovesicles of endocytic origin that enable cellular crosstalk by transferring encapsulated molecular cargos across biological barriers, thereby holding significantly complex implications in the etiology and progression
Shindu C. Thomas   +4 more
doaj   +1 more source

A Novel Glycyrrhetinic Acid-Modified Oxaliplatin Liposome for Liver-Targeting and in vitro/vivo Evaluation [Retraction]

open access: yesDrug Design, Development and Therapy, 2022
Chen J, Jiang H, Wu Y, Li Y, Gao Y. Drug Des Devel Ther. 2015;9:2265–2275. The Editor and Publisher of Drug Design, Development and Therapy wish to retract the published article.
Chen J, Jiang H, Wu Y, Li Y, Gao Y
doaj  

Cellular biodistribution of polymeric nanoparticles in the immune system

open access: yes, 2017
The biodistribution of polymeric nanoparticles (NPs) is of crucial importance in the development of nanoparticle-based vaccine delivery or immunotherapy for cancer.
楊雅雯, Yang, Ya-Wun;Luo, Wen-Hui
core   +1 more source

Biodistribution of VSX-1.

open access: yes, 2023
(A) In vivo imaging of VSX-1’s biodistribution. Labeled VSX (the antibody alone) or VSX-1 (the ADC) was administered to animals IP and monitored by imaging up until 48 hours post-injection (h.p.i.). Both agents distributed throughout the animal (i.e.
Kenneth Johnson (830129)   +16 more
core   +1 more source

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