Results 31 to 40 of about 97,326 (260)

Shi biodistribution and amyloid∶organ ratio.

, 2013
Shi biodistribution and amyloid∶organ ratio.
Ying Huang (53474), Sallie Macy (292365), Angela Williams (292362), Jonathan S. Wall (287997), Dale Schenk (222959), Stephen J. Kennel (288001), Tina Richey (292363), Alan Stuckey (292364), Robert Donnell (292366), Peter Seubert (222943), Robin Barbour (222950)   +10 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Experimental design of optical imaging biodistribution study.

, 2013
Experimental design of optical imaging biodistribution study.
Frauke Alves (77578), Stefania Biffi (381041), Chiara Garrovo (381043), Berislav Bosnjak (381044), Kai Licha (48641), Christian Dullin (77574), Simeone Dal Monego (381042), Michelle M. Epstein (104516), Pia Welker (381045)   +8 more
core   +1 more source

Biodistribution, kinetics, and biological fate of SPION microbubbles in the rat [PDF]

, 2013
Åsa Barrefelt,1,2,* Maryam Saghafian,2,* Raoul Kuiper,3 Fei Ye,4 Gabriella Egri,5 Moritz Klickermann,5 Torkel B Brismar,1 Peter Aspelin,1 Mamoun Muhammed,4 Lars Dähne,5 Moustapha Hassan2,6 1Department of Clinical Science, Intervention and ...
Barrefelt A, Saghafian M, Hassan M, Klickermann M, Aspelin P, Dähne L, Brismar TB, Kuiper R, Muhammed M, Ye F, Egri G, Muhammed, Mamoun,, Ye, F,, Daehne, L, Hassan, Moustapha, Klickermann, M, Saghafian, Maryam, Kuiper, Raoul, Muhammed, M, Klickermann, Moritz, Brismar, TB, Egri, Gabriella, Daehne, Lars, Saghafian, M,, Ye, Fei,, Barrefelt, A, Kuiper, R,, Barrefelt, Åsa, Aspelin, P,, Egri, G, Brismar, Torkel B., Aspelin, Peter   +31 more
core   +1 more source

Monitoring dexamethasone skin biodistribution with ex vivo MALDI-TOF mass spectrometry imaging and confocal Raman microscopy [PDF]

, 2023
Two of the most promising techniques in terms of ex vivo skin imaging and quantifying are confocal Raman microscopy and MALDI-TOF mass spectrometry imaging (MALDI-TOF MSI).
Otero-Espinar, Francisco J., García Berrocoso, Teresa, Vázquez Fernández, Ezequiel, Fernández-Campos, Francisco, Otero Espinar, Francisco J., Pena Rodríguez, Eloy, Pena-Rodríguez, Eloy, Abian Moñux, Joaquín, Abian, Joaquin, Otero Espinar, Francisco Javier, García-Berrocoso, Teresa, Fernández Campos, Francisco, Otero Espinar, Francisco, Eloy Pena-Rodríguez, Teresa García-Berrocoso, Ezequiel Vázquez Fernández, Joaquin Abian, Francisco Fernández-Campos, Francisco J. Otero-Espinar   +18 more
core   +1 more source

Non‐Additive Criteria Assessment in Sustainability Evaluation of High Entropy Alloys: A Toxicity‐Weighted Framework

Advanced Engineering Materials, EarlyView.
Sustainability assessment requires methodologies that appropriately distinguish between additive and non‐additive material properties. A toxicity‐weighted scoring system is developed and applied that accounts for the disproportionate influence of highly toxic constituents through nonlinear weighting functions, providing more realistic estimates than ...
Seth Mehalic, Oladele A. Ogunseitan, Julie M. Schoenung   +2 more
wiley   +1 more source

Biodistribution of Liposome-Encapsulated Bacteriophages and Their Transcytosis During Oral Phage Therapy

Frontiers in Microbiology, 2019
This study sheds light on the biodistribution of orally administered, liposome-encapsulated bacteriophages, and their transcytosis through intestinal cell layers.
Jennifer Otero, Alba García-Rodríguez, Mary Cano-Sarabia, Daniel Maspoch, Daniel Maspoch, Ricard Marcos, Ricard Marcos, Pilar Cortés, Montserrat Llagostera   +8 more
doaj   +1 more source

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

Physiologically based pharmacokinetic modeling of PLGA nanoparticles with varied mPEG content

International Journal of Nanomedicine, 2012
Mingguang Li1, Zoi Panagi2, Konstantinos Avgoustakis2, Joshua Reineke11Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA; 2Pharmaceutical Technology Laboratory ...
Avgoustakis K, Li M, Panagi Z, Reineke J
doaj