Results 61 to 70 of about 97,326 (260)
Dye labeling for optical imaging biases drug carriers' biodistribution and tumor uptake
, 2023 Biodistribution analyses of nanocarriers are often performed with optical imaging. Though dye tags can interact with transporters, e.g., organic anion transporting polypeptides (OATPs), their influence on biodistribution was hardly studied.
Schraven, Sarah +9 more
core +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
International Journal of Nanomedicine, 2019 Yue Yang,1,2 Huihui Bao,1 Qianqian Chai,3 Zhiwen Wang,2 Zhenning Sun,2 Changhui Fu,3 Zhaoping Liu,1 Zhongjie Liu,2 Xianwei Meng,3 Tianlong Liu21China National Center for Food Safety Risk Assessment, Beijing 100022, People’s Republic of China ...
Yang Y +9 more
doaj
Toxics, 2017 The development of different kinds of nanoparticles, showing different physico-chemical properties, has fostered their large use in many fields, including medicine.
Valeria De Matteis
doaj +1 more source
Biodistribution studies in 4T1 tumor-bearing mice.
, 2013 A. Biodistribution of 64Cu-NOTA-TRC105 and 64Cu-DOTA-TRC105 at 24 h post-injection (n = 3). B.
Yunan Yang (337755) +7 more
core +1 more source
Biodistribution data in tumor-bearing mice.
, 2022 Biodistribution of [111In]In-DOTA-TDA (37 kBq) with and without ethiodized oil emulsification in Hep2G tumor-bearing NCG mice at 48 hours post-injection (n = 3, p≤0.0001).
Eleni Liapi (7044791) +6 more
core +1 more source
Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
Advanced Materials, EarlyView.As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang +12 more
wiley +1 more source
Biodistribution of different nanocarriers in murine myoblasts
, 2017 biodistribution study on biocompatible nanocarriers in murine ...
L. Calderan +9 more
core +1 more source
Pharmaceutics, 2020 The alteration of retinoids levels in the skin can cause different disorders in the maturation of epithelial skin cells. Topical administration of these lipophilic molecules is a challenge that can be addressed by encapsulation into drug delivery systems.
Eloy Pena-Rodríguez +4 more
doaj +1 more source
Advanced Materials, EarlyView.Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol +16 more
wiley +1 more source