Results 81 to 90 of about 125,907 (238)

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]

open access: yes, 2010
Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Alink, G.M.   +7 more
core   +2 more sources

Iodine-123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography [PDF]

open access: yes, 2012
Preliminary investigation of the radioiodinated (S,S)-reboxetine analogue, 123I-INER, in baboons showed this tracer to have promise for imaging the noradrenaline transporter (NAT) using single photon emission computed tomography (SPECT).
Baldwin   +26 more
core   +1 more source

Effect of administration route on the biodistribution of albumin microspheres labelled with Re-188 [PDF]

open access: diamond, 2021
В. К. Тищенко   +3 more
openalex   +1 more source

A hyperspectral method to assay the microphysiological fates of nanomaterials in histological samples

open access: yeseLife, 2016
Nanoparticles are used extensively as biomedical imaging probes and potential therapeutic agents. As new particles are developed and tested in vivo, it is critical to characterize their biodistribution profiles.
Elliott D SoRelle   +5 more
doaj   +1 more source

Comparison of technetium-99m IgG with technetium-99m red blood cells labeling in cardiac blood-pool scintigraphy: A preliminary study [PDF]

open access: yes, 2011
This first clinical prospective study was conducted to use of technetium-99m immunoglobulin G (99mTc-IgG) as compared with autologous 99mTc-red blood cells (RBC) in gated blood pool ventriculography.
Amini, A.   +7 more
core  

Physiological biodistribution on Ga68-PSMA PET/CT and the factors effecting biodistribution

open access: yesAnnals of Nuclear Medicine
Abstract Aim The study aims to determine the physiological and pathophysiological distribution of the radiopharmaceutical (Ga68-PSMA-617) and investigate whether there are differences in distribution according to the laboratory, histopathological and clinical findings that can affect image evaluation.
Ayça Arçay Öztürk   +4 more
openaire   +2 more sources

RBC Adherence of Immune Complexes Containing Botulinum Toxin Improves Neutralization and Macrophage Uptake

open access: yesToxins, 2017
In the paralytic disease botulism, the botulinum neurotoxin (BoNT) passes through the bloodstream to reach and inactivate neuromuscular junctions. Monoclonal antibodies (mAbs) may be useful BoNT countermeasures, as mAb combinations can rapidly clear BoNT
Fetweh H. Al-Saleem   +7 more
doaj   +1 more source

Sustained delivery and molecular targeting of a therapeutic monoclonal antibody to metastases in the central nervous system of mice. [PDF]

open access: yes, 2019
Approximately 15-40% of all cancers develop metastases in the central nervous system (CNS), yet few therapeutic options exist to treat them. Cancer therapies based on monoclonal antibodies are widely successful, yet have limited efficacy against CNS ...
Chen, Irvin SY   +17 more
core  

Biodistribution of Nanomedicines [PDF]

open access: yesMolecular Pharmaceutics, 2008
Eric, Simanek, Anil K, Patri
openaire   +2 more sources

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