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Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating gene expression. The majority of miRNAs are transcribed from DNA sequences into primary miRNAs and processed into precursor miRNAs, and finally mature miRNAs.
Heyam Hayder, Chun Peng
exaly +2 more sources
Aging is a general degenerative process related to deterioration of cell functions in the entire organism. Mitochondria, which play a key role in energy homeostasis and metabolism of reactive oxygen species (ROS), require lifetime control and constant ...
Artem P Gureev, Vasily N Popov
exaly +2 more sources
Paracrine and endocrine roles have increasingly been ascribed to extracellular vesicles (EVs) generated by multicellular organisms. Central to the biogenesis, content, and function of EVs are their delimiting lipid bilayer membranes. To evaluate research
Emanuele Cocucci+2 more
exaly +2 more sources
The Biogenesis, Functions, and Challenges of Circular RNAs
Xiang Li, Li Yang, Ling-ling Chen
exaly +2 more sources
Ancestral Stem Cell Reprogramming Genes Active in Hemichordate Regeneration
Hemichordate enteropneust worms regenerate extensively in a manner that resembles the regeneration for which planaria and hydra are well known.
Tom Humphreys+11 more
doaj +1 more source
The Machinery of Exosomes: Biogenesis, Release, and Uptake
Exosomes are a subtype of membrane-contained vesicles 40–200 nm in diameter that are secreted by cells into their surroundings. By transporting proteins, lipids, mRNA, miRNA, lncRNA, and DNA, exosomes are able to perform such vital functions as ...
S. V. Krylova, Daorong Feng
semanticscholar +1 more source
MicroRNA biogenesis pathways in cancer
Shuibin Lin, Richard I Gregory
exaly +2 more sources
Genetically-biased fertilization in APOBEC1 complementation factor (A1cf) mutant mice
Meiosis, recombination, and gametogenesis normally ensure that gametes combine randomly. But in exceptional cases, fertilization depends on the genetics of gametes from both females and males. A key question is whether their non-random union results from
Naoki Hirose+8 more
doaj +1 more source
Staphylococcus aureus represent a serious threat to public health due to food safety, antibiotic resistance, and the potential zoonotic transmission of strains between dairy cattle and humans. Biofilm formation by S.
Giovanny Torres+5 more
doaj +1 more source
Current Studies of Mitochondrial Quality Control in the Preeclampsia
Mitochondria are cellular energy powerhouses that play important roles in regulating cellular processes. Mitochondrial quality control (mQC), including mitochondrial biogenesis, mitophagy, mitochondrial fusion and fission, maintains physiological demand ...
Xiaoqing Peng+9 more
doaj +1 more source