Results 1 to 10 of about 439,213 (293)

PIWI proteins tether the piRNA biogenesis machinery to mitochondria during mammalian spermatogenesis. [PDF]

EMBO J
Gao J, Chen C, Shang G, Yu W, Zhao T, Zhang Y, Chen C, Ding D.   +7 more
europepmc   +2 more sources

Ancestral Stem Cell Reprogramming Genes Active in Hemichordate Regeneration

Frontiers in Ecology and Evolution, 2022
Hemichordate enteropneust worms regenerate extensively in a manner that resembles the regeneration for which planaria and hydra are well known.
Tom Humphreys, Keith Weiser, Asuka Arimoto, Akane Sasaki, Gene Uenishi, Brent Fujimoto, Takeshi Kawashima, Kekoa Taparra, Janos Molnar, Noriyuki Satoh, Yusuke Marikawa, Kuni Tagawa   +11 more
doaj   +1 more source

Experimental and computational workflow for the analysis of tRNA pools from eukaryotic cells by mim-tRNAseq

STAR Protocols, 2022
Summary: Quantifying tRNAs is crucial for understanding how they regulate mRNA translation but is hampered by their extensive sequence similarity and premature termination of reverse transcription at multiple modified nucleotides.
Andrew Behrens, Danny D. Nedialkova
doaj   +1 more source

Phenotypic Characterization and Whole Genome Analysis of a Strong Biofilm-Forming Staphylococcus aureus Strain Associated With Subclinical Bovine Mastitis in Colombia

Frontiers in Veterinary Science, 2020
Staphylococcus aureus represent a serious threat to public health due to food safety, antibiotic resistance, and the potential zoonotic transmission of strains between dairy cattle and humans. Biofilm formation by S.
Giovanny Torres, Giovanny Torres, Karen Vargas, Yesid Cuesta-Astroz, Julián Reyes-Vélez, Martha Olivera-Angel   +5 more
doaj   +1 more source

Genetically-biased fertilization in APOBEC1 complementation factor (A1cf) mutant mice

Scientific Reports, 2022
Meiosis, recombination, and gametogenesis normally ensure that gametes combine randomly. But in exceptional cases, fertilization depends on the genetics of gametes from both females and males. A key question is whether their non-random union results from
Naoki Hirose, Genevieve Blanchet, Yasuhiro Yamauchi, Abigail C. Snow, Robin Friedman, Carmen Y. Khoo, Christine W. Lary, Monika A. Ward, Joseph H. Nadeau   +8 more
doaj   +1 more source

Proteomic Analysis of Lipid Droplets from Arabidopsis Aging Leaves Brings New Insight into Their Biogenesis and Functions

Frontiers in Plant Science, 2017
Lipid droplets (LDs) are cell compartments specialized for oil storage. Although their role and biogenesis are relatively well documented in seeds, little is known about their composition, structure and function in senescing leaves where they also ...
Lysiane Brocard, Françoise Immel, Françoise Immel, Denis Coulon, Denis Coulon, Denis Coulon, Nicolas Esnay, Nicolas Esnay, Karine Tuphile, Karine Tuphile, Stéphanie Pascal, Stéphanie Pascal, Stéphane Claverol, Laëtitia Fouillen, Laëtitia Fouillen, Jean-Jacques Bessoule, Jean-Jacques Bessoule, Claire Bréhélin, Claire Bréhélin   +18 more
doaj   +1 more source

Outer Membrane Vesicles from Acinetobacter baumannii: Biogenesis, Functions, and Vaccine Application

Vaccines, 2023
This review focuses on Acinetobacter baumannii, a Gram-negative bacterium that causes various infections and whose multidrug resistance has become a significant challenge in clinical practices. There are multiple bacterial mechanisms in A. baumannii that
Zheqi Weng, Ning Yang, Shujun Shi, Zining Xu, Zixu Chen, Chen Liang, Xiuwei Zhang, Xingran Du   +7 more
doaj   +1 more source

Effective Targeted Gene Knockdown in Mammalian Cells Using the piggyBac Transposase-based Delivery System

Molecular Therapy: Nucleic Acids, 2013
Nonviral gene delivery systems are rapidly becoming a desirable and applicable method to overexpress genes in various types of cells. We have recently developed a piggyBac transposase-based, helper-independent and self-inactivating delivery system ...
Jesse B Owens, Juanita Mathews, Philip Davy, Ilko Stoytchev, Stefan Moisyadi, Rich Allsopp   +5 more
doaj   +1 more source

From Promise to Reality: Bioengineering Strategies to Enhance the Therapeutic Potential of Extracellular Vesicles

Bioengineering, 2022
Extracellular vesicles (EVs) have been the focus of great attention over the last decade, considering their promising application as next-generation therapeutics.
Miguel de Almeida Fuzeta, Pedro P. Gonçalves, Ana Fernandes-Platzgummer, Joaquim M. S. Cabral, Nuno Bernardes, Cláudia L. da Silva   +5 more
doaj   +1 more source

Postconditioning with D-limonene exerts neuroprotection in rats via enhancing mitochondrial activity

Türk Biyokimya Dergisi, 2023
The key component of neuroprotection after cerebral ischemia–reperfusion (I–R) injury is mitochondrial improvement. By focusing on the function of mitochondrial biogenesis and ATP-sensitive potassium (mK–ATP) channels and inflammatory responses, the ...
Zhang Leguo, Zhao Zeyu, Jia Jianpu, Zhang Liran, Xia Ruixue, Zhu Cuimin   +5 more
doaj   +1 more source