Results 11 to 20 of about 12,509 (114)
The biogenesis of mitochondria [PDF]
INTRODUCTION 251 MITOCHONDRIAL DNA . . . . . . . . . . . . . . . . . . .. . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 SYNTHESIS AND TURNOVER OF MITOCHONDRIAL DNA . . . . .. . . .. . .. ... . .. ... 256 MITOCHONDRIAL RNA AND MITOCHONDRIAL RIBOSOMES 257 SYNTHESIS OF MITOCHONDRIAL RNA . . . . . . . . . . . . . . . . . . . . . . . . .
M, Ashwell, T S, Work
openaire +4 more sources
Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and protects cells from potentially harmful agents that may accumulate in the cytoplasm, including pathogens, protein aggregates, and dysfunctional organelles. This process is initiated by the formation of a phagophore membrane, which wraps around a portion of
Yan Zhen, Harald Stenmark
openaire +4 more sources
The Biogenesis of Chylomicrons [PDF]
The absorption of dietary fat is of increasing concern given the rise of obesity not only in the United States but throughout the developed world. This review explores what happens to dietary fat within the enterocyte. Absorbed fatty acids and monoacylglycerols are required to be bound to intracellular proteins and/or to be rapidly converted to ...
Charles M, Mansbach, Shadab A, Siddiqi
openaire +3 more sources
The Golgi is an essential membrane-bound organelle in the secretary pathway of eukaryotic cells. In mammalian cells, the Golgi stacks are integrated into a continuous perinuclear ribbon, which poses a challenge for the daughter cells to inherit this membrane organelle during cell division.
Yanzhuang, Wang, Joachim, Seemann
openaire +2 more sources
Sphingolipids in the trans-Golgi network have been implicated in polar trafficking. Here Wattelet-Boyer et al. show that hydroxylated C24- and C26-acyl-chain sphingolipids are enriched in trans-Golgi network subdomains that are critical for polar sorting
Valérie Wattelet-Boyer +10 more
doaj +1 more source
Mitochondria are double-membrane organelles that contain their own genome, the mitochondrial DNA (mtDNA), and reminiscent of its endosymbiotic origin.
Stefan Geldon +2 more
doaj +1 more source
Plasmodesmata (PD) are nanometric (~20 nm wide) membrane lined pores encased in the cell walls of the adjacent plant cells. They allow the cells to exchange all types of molecules ranging from nutrients like sugar, hormones, to RNAs and various proteins.
William Nicolas +2 more
doaj +1 more source
Lipids or Proteins: Who Is Leading the Dance at Membrane Contact Sites?
Understanding the mode of action of membrane contact sites (MCSs) across eukaryotic organisms at the near-atomic level to infer function at the cellular and tissue levels is a challenge scientists are currently facing. These peculiar systems dedicated to
Jules D. Petit +4 more
doaj +1 more source
Poly(ADP-ribose) polymerase 1 (PARP1) is established as a key regulator of the cellular DNA damage response and apoptosis. In addition, PARP1 participates in the global regulation of DNA repair, transcription, telomere maintenance, and inflammation ...
Nikita V. Savelyev +10 more
doaj +1 more source
Peroxisome biogenesis and peroxisome biogenesis disorders
Peroxisome assembly in mammals requires more than 15 genes. Two isoforms of the peroxisome targeting signal type 1 (PTS1) receptor, Pex5pS and Pex5pL, are identified in mammals. Pex5pS and Pex5pL bind PTS1 proteins. Pex5pL, but not Pex5pS, directly interacts with the PTS2 receptor, Pex7p, carrying its cargo PTS2 protein in the cytosol.
openaire +2 more sources

