Results 11 to 20 of about 12,509 (114)

The biogenesis of mitochondria [PDF]

open access: yesBiochemical Journal, 1970
INTRODUCTION 251 MITOCHONDRIAL DNA . . . . . . . . . . . . . . . . . . .. . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 SYNTHESIS AND TURNOVER OF MITOCHONDRIAL DNA . . . . .. . . .. . .. ... . .. ... 256 MITOCHONDRIAL RNA AND MITOCHONDRIAL RIBOSOMES 257 SYNTHESIS OF MITOCHONDRIAL RNA . . . . . . . . . . . . . . . . . . . . . . . . .
M, Ashwell, T S, Work
openaire   +4 more sources

Autophagosome Biogenesis

open access: yesCells, 2023
Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and protects cells from potentially harmful agents that may accumulate in the cytoplasm, including pathogens, protein aggregates, and dysfunctional organelles. This process is initiated by the formation of a phagophore membrane, which wraps around a portion of
Yan Zhen, Harald Stenmark
openaire   +4 more sources

The Biogenesis of Chylomicrons [PDF]

open access: yesAnnual Review of Physiology, 2010
The absorption of dietary fat is of increasing concern given the rise of obesity not only in the United States but throughout the developed world. This review explores what happens to dietary fat within the enterocyte. Absorbed fatty acids and monoacylglycerols are required to be bound to intracellular proteins and/or to be rapidly converted to ...
Charles M, Mansbach, Shadab A, Siddiqi
openaire   +3 more sources

Golgi Biogenesis [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2011
The Golgi is an essential membrane-bound organelle in the secretary pathway of eukaryotic cells. In mammalian cells, the Golgi stacks are integrated into a continuous perinuclear ribbon, which poses a challenge for the daughter cells to inherit this membrane organelle during cell division.
Yanzhuang, Wang, Joachim, Seemann
openaire   +2 more sources

Enrichment of hydroxylated C24- and C26-acyl-chain sphingolipids mediates PIN2 apical sorting at trans-Golgi network subdomains

open access: yesNature Communications, 2016
Sphingolipids in the trans-Golgi network have been implicated in polar trafficking. Here Wattelet-Boyer et al. show that hydroxylated C24- and C26-acyl-chain sphingolipids are enriched in trans-Golgi network subdomains that are critical for polar sorting
Valérie Wattelet-Boyer   +10 more
doaj   +1 more source

Redox-Mediated Regulation of Mitochondrial Biogenesis, Dynamics, and Respiratory Chain Assembly in Yeast and Human Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
Mitochondria are double-membrane organelles that contain their own genome, the mitochondrial DNA (mtDNA), and reminiscent of its endosymbiotic origin.
Stefan Geldon   +2 more
doaj   +1 more source

Electron Tomography to Study the Three-dimensional Structure of Plasmodesmata in Plant Tissues–from High Pressure Freezing Preparation to Ultrathin Section Collection

open access: yesBio-Protocol, 2018
Plasmodesmata (PD) are nanometric (~20 nm wide) membrane lined pores encased in the cell walls of the adjacent plant cells. They allow the cells to exchange all types of molecules ranging from nutrients like sugar, hormones, to RNAs and various proteins.
William Nicolas   +2 more
doaj   +1 more source

Lipids or Proteins: Who Is Leading the Dance at Membrane Contact Sites?

open access: yesFrontiers in Plant Science, 2019
Understanding the mode of action of membrane contact sites (MCSs) across eukaryotic organisms at the near-atomic level to infer function at the cellular and tissue levels is a challenge scientists are currently facing. These peculiar systems dedicated to
Jules D. Petit   +4 more
doaj   +1 more source

PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins

open access: yesFrontiers in Cell and Developmental Biology, 2021
Poly(ADP-ribose) polymerase 1 (PARP1) is established as a key regulator of the cellular DNA damage response and apoptosis. In addition, PARP1 participates in the global regulation of DNA repair, transcription, telomere maintenance, and inflammation ...
Nikita V. Savelyev   +10 more
doaj   +1 more source

Peroxisome biogenesis and peroxisome biogenesis disorders

open access: yesFEBS Letters, 2000
Peroxisome assembly in mammals requires more than 15 genes. Two isoforms of the peroxisome targeting signal type 1 (PTS1) receptor, Pex5pS and Pex5pL, are identified in mammals. Pex5pS and Pex5pL bind PTS1 proteins. Pex5pL, but not Pex5pS, directly interacts with the PTS2 receptor, Pex7p, carrying its cargo PTS2 protein in the cytosol.
openaire   +2 more sources

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