Results 21 to 30 of about 12,509 (114)
Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7
EMBO Molecular Medicine, 2019 Nuclear and mitochondrial genome mutations lead to various mitochondrial diseases, many of which affect the mitochondrial respiratory chain. The proteome of the intermembrane space (IMS) of mitochondria consists of several important assembly factors that
Karthik Mohanraj +13 more
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Heliyon, 2019 The ability of Staphylococcus aureus to form biofilms is an important virulence factor because this has been associated with persistent bovine intramammary infections. Different mechanisms of biofilm formation have been described in S.
G. Torres +4 more
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Biomolecules, 2020 The human small RNA miR-4443 is functionally involved in several types of cancer and in the biology of the immune system, downstream of insulin and leptin signaling.
Ari Meerson
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Outer Membrane Vesicles from Acinetobacter baumannii: Biogenesis, Functions, and Vaccine Application
Vaccines, 2023 This review focuses on Acinetobacter baumannii, a Gram-negative bacterium that causes various infections and whose multidrug resistance has become a significant challenge in clinical practices. There are multiple bacterial mechanisms in A. baumannii that
Zheqi Weng +7 more
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Endoplasmic Reticulum Membrane and Contact Site Dynamics in Autophagy Regulation and Stress Response
Frontiers in Cell and Developmental Biology, 2020 Autophagy mobilizes a variety of intracellular endomembranes to ensure a proper stress response and the maintenance of cellular homeostasis. While the process of de novo biogenesis of pre-autophagic structures is not yet fully characterized, the role of ...
Etienne Morel
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The biogenesis of the immunopeptidome
Seminars in Immunology, 2023 The immunopeptidome is the repertoire of peptides bound and presented by the MHC class I, class II, and non-classical molecules. The peptides are produced by the degradation of most cellular proteins, and in some cases, peptides are produced from extracellular proteins taken up by the cells.
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THE BIOGENESIS OF THE MOLD TROPOLONES [PDF]
Proceedings of the National Academy of Sciences, 1960 The discovery of the mold metabolites puberulonic acid (I) and puberulic acid (II)(1) and stipitatic acid (III)(2) presented a difficult structural problem to organic chemistry until, in 1945, Dewar(3) made the ingenious proposal of the existence of tropolone (IV) as a new aromatic system.
Ferretti, L. D., Richards, J. H.
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The dynamics and functional impact of tRNA repertoires during early embryogenesis in zebrafish
The EMBO JournalEmbryogenesis entails dramatic shifts in mRNA translation and turnover that reprogram gene expression during cellular proliferation and differentiation.
Madalena M Reimão-Pinto +5 more
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Platelet bioreactor: accelerated evolution of design and manufacture
Platelets, 2017 Platelets, responsible for clot formation and blood vessel repair, are produced by megakaryocytes in the bone marrow. Platelets are critical for hemostasis and wound healing, and are often provided following surgery, chemotherapy, and major trauma ...
Jonathan N. Thon +2 more
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The Biogenesis and Functions of Exosomes [PDF]
Traffic, 2002 Exosomes are membrane vesicles with a diameter of 40–100 nm that are secreted by many cell types into the extracellular milieu. They correspond to the internal vesicles of an endosomal compartment, the multivesicular body and are released upon exocytic fusion of this organelle with the plasma membrane. Intracellularly, they are formed by inward budding
Stoorvogel, Willem +3 more
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