Results 21 to 30 of about 290,493 (308)
Cell Reports, 2015 The RNA exosome complex constitutes the major nuclear eukaryotic 3′-5′ exonuclease. Outside of nucleoli, the human nucleoplasmic exosome is directed to some of its substrates by the nuclear exosome targeting (NEXT) complex.
Michal Lubas +5 more
doaj +1 more source
Nature Communications, 2016 Sphingolipids in the trans-Golgi network have been implicated in polar trafficking. Here Wattelet-Boyer et al. show that hydroxylated C24- and C26-acyl-chain sphingolipids are enriched in trans-Golgi network subdomains that are critical for polar sorting
Valérie Wattelet-Boyer +10 more
doaj +1 more source
Disruption of ribosome biogenesis triggers a p21/p53-mediated cell cycle checkpoint [PDF]
, 2006 Cell cycle entry requires a dramatic increase in protein production. In order to cope with this demand, the cell must upregulate ribosome biogenesis. Given that ribosome biogenesis is the most energy-consuming anabolic process in a growing cell, and ...
Di Cara, Alessandro
core +1 more source
Bio-Protocol, 2018 Plasmodesmata (PD) are nanometric (~20 nm wide) membrane lined pores encased in the cell walls of the adjacent plant cells. They allow the cells to exchange all types of molecules ranging from nutrients like sugar, hormones, to RNAs and various proteins.
William Nicolas +2 more
doaj +1 more source
Lipids or Proteins: Who Is Leading the Dance at Membrane Contact Sites?
Frontiers in Plant Science, 2019 Understanding the mode of action of membrane contact sites (MCSs) across eukaryotic organisms at the near-atomic level to infer function at the cellular and tissue levels is a challenge scientists are currently facing. These peculiar systems dedicated to
Jules D. Petit +4 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Poly(ADP-ribose) polymerase 1 (PARP1) is established as a key regulator of the cellular DNA damage response and apoptosis. In addition, PARP1 participates in the global regulation of DNA repair, transcription, telomere maintenance, and inflammation ...
Nikita V. Savelyev +10 more
doaj +1 more source
Molecular genetic analysis of siRNA biogenesis and function in Arabidopsis thaliana [PDF]
, 2009 In diverse eukaryotes, small RNA products of Dicer-like (DCL) proteins regulate mRNA stability or translation, and direct chromatin modifications to genomic regions, phenomena collectively known as RNA silencing.
Blevins, Todd Lucas
core +1 more source
, 2022 This Open Access volume provides comprehensive reviews and describes the latest techniques to study eukaryotic ribosome biogenesis. For more than 50 years ribosomes are a major research topic.
core +3 more sources
Biomolecules, 2020 The human small RNA miR-4443 is functionally involved in several types of cancer and in the biology of the immune system, downstream of insulin and leptin signaling.
Ari Meerson
doaj +1 more source
Outer Membrane Vesicles from Acinetobacter baumannii: Biogenesis, Functions, and Vaccine Application
Vaccines, 2023 This review focuses on Acinetobacter baumannii, a Gram-negative bacterium that causes various infections and whose multidrug resistance has become a significant challenge in clinical practices. There are multiple bacterial mechanisms in A. baumannii that
Zheqi Weng +7 more
doaj +1 more source