Results 31 to 40 of about 290,493 (308)

Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7

EMBO Molecular Medicine, 2019
Nuclear and mitochondrial genome mutations lead to various mitochondrial diseases, many of which affect the mitochondrial respiratory chain. The proteome of the intermembrane space (IMS) of mitochondria consists of several important assembly factors that
Karthik Mohanraj, Michal Wasilewski, Cristiane Benincá, Dominik Cysewski, Jaroslaw Poznanski, Paulina Sakowska, Zaneta Bugajska, Markus Deckers, Sven Dennerlein, Erika Fernandez‐Vizarra, Peter Rehling, Michal Dadlez, Massimo Zeviani, Agnieszka Chacinska   +13 more
doaj   +1 more source

Genotypic and phenotypic characterization of biofilm production by Staphylococcus aureus strains isolated from bovine intramammary infections in Colombian dairy farms

Heliyon, 2019
The ability of Staphylococcus aureus to form biofilms is an important virulence factor because this has been associated with persistent bovine intramammary infections. Different mechanisms of biofilm formation have been described in S.
G. Torres, K. Vargas, M. Sánchez-Jiménez, J. Reyes-Velez, M. Olivera-Angel   +4 more
doaj   +1 more source

Endoplasmic Reticulum Membrane and Contact Site Dynamics in Autophagy Regulation and Stress Response

Frontiers in Cell and Developmental Biology, 2020
Autophagy mobilizes a variety of intracellular endomembranes to ensure a proper stress response and the maintenance of cellular homeostasis. While the process of de novo biogenesis of pre-autophagic structures is not yet fully characterized, the role of ...
Etienne Morel
doaj   +1 more source

40S ribosome biogenesis co-factors are essential for gametophyte and embryo development

, 2013
Ribosome biogenesis is well described in Saccharomyces cerevisiae. In contrast only very little information is available on this pathway in plants. This study presents the characterization of five putative protein co-factors of ribosome biogenesis in ...
Roman Martin, Martin, Roman, Roman Martin (85483), Simm, Stefan, Markus T. Bohnsack, Markus T Bohnsack, Benjamin L. Weis (277837), Stefan Simm, Sandra Missbach (277836), Markus T. Bohnsack (277840), Benjamin L Weis, Enrico Schleiff, Weis, Benjamin L., Sandra Missbach, Bohnsack, Markus, Mißbach, Sandra, Stefan Simm (277838), Schleiff, Enrico, Enrico Schleiff (49377), Lafontaine, Denis, Bohnsack, Markus T., Ra Missbach, Benjamin L. Weis   +22 more
core   +1 more source

Peroxisome biogenesis and peroxisome biogenesis disorders

FEBS Letters, 2000
Peroxisome assembly in mammals requires more than 15 genes. Two isoforms of the peroxisome targeting signal type 1 (PTS1) receptor, Pex5pS and Pex5pL, are identified in mammals. Pex5pS and Pex5pL bind PTS1 proteins. Pex5pL, but not Pex5pS, directly interacts with the PTS2 receptor, Pex7p, carrying its cargo PTS2 protein in the cytosol.
openaire   +2 more sources

Biogenesis 1.0

, 2016
<p>Docker Biogenesis is the junction of two softwares:</p> <p><strong><em>Biogenesis</em></strong> is an artificial life program that simulates the processes involved in the evolution of organisms.
Menegidio, FB, Menegidio, FB (5283721)
core   +1 more source

Peroxisome biogenesis in Hansenula polymorpha: different mutations in genes, essential for peroxisome biogenesis, cause different peroxisomal mutant phenotypes [PDF]

, 1992
In Hansenula polymorpha, different monogenic recessive mutations mapped in either of two previously identified genes, PER1 and PER3, produced different peroxisomal mutant phenotypes.
Titorenko, V. I., Harder, Wim, Waterham, H. R., Waterham, Hans R., Haima, Peter, Titorenko, Vladimir I.,, Titorenko, Vladimir I., Harder, Wim,, Haima, Peter,, Veenhuis, Marten,, Veenhuis, M., Veenhuis, Marten, Harder, W., Haima, P., Waterham, Hans R.,   +14 more
core   +1 more source

Platelet bioreactor: accelerated evolution of design and manufacture

Platelets, 2017
Platelets, responsible for clot formation and blood vessel repair, are produced by megakaryocytes in the bone marrow. Platelets are critical for hemostasis and wound healing, and are often provided following surgery, chemotherapy, and major trauma ...
Jonathan N. Thon, Brad J. Dykstra, Lea M. Beaulieu   +2 more
doaj   +1 more source

The Biogenesis, Biology, and Clinical Significance of Exosomal PD-L1 in Cancer

Frontiers in Immunology, 2020
The exosome serves as a trafficking vehicle for transport of programmed death-ligand 1 (PD-L1) into receptor cells. In tumor microenvironment, distant tumor cells can remotely attack activated T cells by exosomal PD-L1.
Yanyan Tang, Yanyan Tang, Yanyan Tang, Ping Zhang, Ping Zhang, Yumin Wang, Jinpeng Wang, Jinpeng Wang, Min Su, Min Su, Ying Wang, Ying Wang, Lianqing Zhou, Jumei Zhou, Jumei Zhou, Wei Xiong, Wei Xiong, Zhaoyang Zeng, Zhaoyang Zeng, Yujuan Zhou, Shaolin Nie, Shaolin Nie, Qianjin Liao, Qianjin Liao   +23 more
doaj   +1 more source

Identification, biogenesis, function, and mechanism of action of circular RNAs in plants

Plant Communications, 2023
Circular RNAs (circRNAs) are a class of single-stranded, closed RNA molecules with unique functions that are ubiquitously expressed in all eukaryotes.
Ruiqi Liu, Yu Ma, Tao Guo, Guanglin Li
doaj   +1 more source