Results 21 to 30 of about 449,966 (339)

The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells. [PDF]

, 2017
Transfer RNAs (tRNAs) function in translational machinery and further serves as a source of short non-coding RNAs (ncRNAs). tRNA-derived ncRNAs show differential expression profiles and play roles in many biological processes beyond translation ...
Honda, Shozo, Kawamura, Takuya, Kirino, PhD, Yohei, Loher, Phillipe, Morichika, Keisuke, Rigoutsos, Isidore   +5 more
core   +2 more sources

Peroxisome Biogenesis Disorders

Translational Science of Rare Diseases, 2016
The peroxisome biogenesis disorders (PBD) are a heterogeneous group of autosomal recessive disorders in which peroxisome assembly is impaired, leading to deficiencies of peroxisomal enzymes, complex developmental sequelae and progressive disabilities.
Argyriou, Catherine, D’Agostino, Maria Daniela, Braverman, Nancy   +2 more
openaire   +3 more sources

Enrichment of hydroxylated C24- and C26-acyl-chain sphingolipids mediates PIN2 apical sorting at trans-Golgi network subdomains

Nature Communications, 2016
Sphingolipids in the trans-Golgi network have been implicated in polar trafficking. Here Wattelet-Boyer et al. show that hydroxylated C24- and C26-acyl-chain sphingolipids are enriched in trans-Golgi network subdomains that are critical for polar sorting
Valérie Wattelet-Boyer, Lysiane Brocard, Kristoffer Jonsson, Nicolas Esnay, Jérôme Joubès, Frédéric Domergue, Sébastien Mongrand, Natasha Raikhel, Rishikesh P. Bhalerao, Patrick Moreau, Yohann Boutté   +10 more
doaj   +1 more source

Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis [PDF]

, 2016
Funding The study was funded entirely by institutional funds.Peer ...
Galley, H. F., Lowes, D. A., McCreath, G., Scullion, M. M. F., Webster, N. R.   +4 more
core   +1 more source

Electron Tomography to Study the Three-dimensional Structure of Plasmodesmata in Plant Tissues–from High Pressure Freezing Preparation to Ultrathin Section Collection

Bio-Protocol, 2018
Plasmodesmata (PD) are nanometric (~20 nm wide) membrane lined pores encased in the cell walls of the adjacent plant cells. They allow the cells to exchange all types of molecules ranging from nutrients like sugar, hormones, to RNAs and various proteins.
William Nicolas, Emmanuelle Bayer, Lysiane Brocard   +2 more
doaj   +1 more source

Retrograde trafficking of Argonaute 2 acts as a rate-limiting step for de novo miRNP formation on endoplasmic reticulum–attached polysomes in mammalian cells [PDF]

, 2020
microRNAs are short regulatory RNAs in metazoan cells. Regulation of miRNA activity and abundance is evident in human cells where availability of target messages can influence miRNA biogenesis by augmenting the Dicer1-dependent processing of precursors ...
Barman, Bahnisikha, Bhattacharyya, Suvendra N., Bose, Mainak, Chakrabarty, Yogaditya, Chatterjee, Susanta   +4 more
core  

Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion [PDF]

, 2013
Toxoplasma (toxoplasmosis) and Plasmodium (malaria) use unique secretory organelles for migration, cell invasion, manipulation of host cell functions, and cell egress. In particular, the apical secretory micronemes and rhoptries of apicomplexan parasites
A Fomovska, AE Topolska, B Lige, B Shen, BF Kafsack, BJ Luft, C Lord, CA Hunter, Chetan E. Chitnis, Christian Slomianny, CY He, D Richard, DL Alexander, F Parussini, H El Hajj, HC Hoppe, HC Hoppe, I Mellman, J Schrevel, JB Dacks, JC Boothroyd, JE Rothman, JF Dubremetz, JM Harper, K Kremer, K Miranda, KA Joiner, KA Joiner, KM Hager, L Pelletier, L Sheiner, LH Bannister, LH Bannister, LM Kats, M Elias, M Tufet-Bayona, M Yang, Markus Meissner, ME Francia, MH Ngo, MH Ngo, MK Shaw, MS Breinich, MS Marks, NA Counihan, PJ Bradley, PJ Sloves, S Mogelsvang, SD Brydges, Stanislas Tomavo, VB Carruthers, Vern B. Carruthers, WM Henne, X Que, Z Dou   +54 more
core   +2 more sources

Lipids or Proteins: Who Is Leading the Dance at Membrane Contact Sites?

Frontiers in Plant Science, 2019
Understanding the mode of action of membrane contact sites (MCSs) across eukaryotic organisms at the near-atomic level to infer function at the cellular and tissue levels is a challenge scientists are currently facing. These peculiar systems dedicated to
Jules D. Petit, Jules D. Petit, Françoise Immel, Laurence Lins, Emmanuelle M. Bayer   +4 more
doaj   +1 more source

Phytochrome activates the plastid-encoded RNA polymerase for chloroplast biogenesis via nucleus-to-plastid signaling. [PDF]

, 2019
Light initiates chloroplast biogenesis by activating photosynthesis-associated genes encoded by not only the nuclear but also the plastidial genome, but how photoreceptors control plastidial gene expression remains enigmatic.
Blaha, Gregor M, Cao, Jun, Chen, Meng, Pasoreck, Elise K, Wang, He, Weigel, Detlef, Yoo, Chan Yul   +6 more
core   +2 more sources

PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins

Frontiers in Cell and Developmental Biology, 2021
Poly(ADP-ribose) polymerase 1 (PARP1) is established as a key regulator of the cellular DNA damage response and apoptosis. In addition, PARP1 participates in the global regulation of DNA repair, transcription, telomere maintenance, and inflammation ...
Nikita V. Savelyev, Nikita V. Savelyev, Nikita M. Shepelev, Olga I. Lavrik, Olga I. Lavrik, Maria P. Rubtsova, Maria P. Rubtsova, Olga A. Dontsova, Olga A. Dontsova, Olga A. Dontsova, Olga A. Dontsova   +10 more
doaj   +1 more source