Results 1 to 10 of about 1,093,449 (328)

Navigating the Landscape: A Comprehensive Review of Current Virus Databases

Viruses, 2023
Viruses are abundant and diverse entities that have important roles in public health, ecology, and agriculture. The identification and surveillance of viruses rely on an understanding of their genome organization, sequences, and replication strategy ...
Muriel Ritsch, Noriko A. Cassman, Shahram Saghaei, Manja Marz   +3 more
doaj   +1 more source

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]

PeerJ, 2013
Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun, Yuliya Kremenska, Vrundha M. Nair, Maksym Kremenskoy, Baby Joseph, Igor V. Kurochkin   +5 more
doaj   +2 more sources

Decoding cell-type contributions to the cfRNA transcriptomic landscape of liver cancer

Human Genomics, 2023
Background Liquid biopsy, particularly cell-free RNA (cfRNA), has emerged as a promising non-invasive diagnostic tool for various diseases, including cancer, due to its accessibility and the wealth of information it provides.
Aram Safrastyan, Christian Höner zu Siederdissen, Damian Wollny   +2 more
doaj   +1 more source

Advances in Non-Coding RNA Sequencing

Non-Coding RNA, 2021
Non-coding RNAs (ncRNAs) comprise a set of abundant and functionally diverse RNA molecules. Since the discovery of the first ncRNA in the 1960s, ncRNAs have been shown to be involved in nearly all steps of the central dogma of molecular biology.
Julia Micheel, Aram Safrastyan, Damian Wollny   +2 more
doaj   +1 more source

Rust-Bio - a fast and safe bioinformatics library [PDF]

, 2015
We present Rust-Bio, the first general purpose bioinformatics library for the innovative Rust programming language. Rust-Bio leverages the unique combination of speed, memory safety and high-level syntax offered by Rust to provide a fast and safe set of ...
Köster, Johannes
core   +5 more sources

The Role of Non-Coding RNAs in the Human Placenta

Cells, 2022
Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs, and species, which has been broadly recognized since the human ENCODE project and several other genome projects.
Milena Žarković, Franziska Hufsky, Udo R. Markert, Manja Marz   +3 more
doaj   +1 more source

Genomic analysis of 61 Chlamydia psittaci strains reveals extensive divergence associated with host preference

BMC Genomics, 2023
Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse, Martin Hölzer, Fabien Vorimore, Lisa-Marie Barf, Carsten Sachse, Karine Laroucau, Manja Marz, Kevin Lamkiewicz   +7 more
doaj   +1 more source

Bioinformatics analysis of DLGAP5 as a biomarker in lung adenocarcinoma: implications for immune infiltration and targeted therapy. [PDF]

Discov Oncol
Jiao L, Xu X, Liu Y, Li F, Li C, Wu T.
europepmc   +2 more sources

Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets

BMC Genomics, 2017
Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease ...
Vladimir A. Kuznetsov, Zhiqun Tang, Anna V. Ivshina   +2 more
doaj   +1 more source

IMPLANT: a new technique for transgene copy number estimation in plants using a single end-point PCR reaction

Plant Methods, 2022
Background Copy number determination is one of the first steps in the characterization of transgenic plant lines. The classical approach to this, Southern blotting, is time-consuming, expensive and requires massive amounts of high-quality genomic DNA ...
Jonas De Saeger, Jihae Park, Kai Thoris, Charlotte De Bruyn, Hoo Sun Chung, Dirk Inzé, Stephen Depuydt   +6 more
doaj   +1 more source