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Navigating the Landscape: A Comprehensive Review of Current Virus Databases
Viruses, 2023 Viruses are abundant and diverse entities that have important roles in public health, ecology, and agriculture. The identification and surveillance of viruses rely on an understanding of their genome organization, sequences, and replication strategy ...
Muriel Ritsch +3 more
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Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]
PeerJ, 2013 Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun +5 more
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Decoding cell-type contributions to the cfRNA transcriptomic landscape of liver cancer
Human Genomics, 2023 Background Liquid biopsy, particularly cell-free RNA (cfRNA), has emerged as a promising non-invasive diagnostic tool for various diseases, including cancer, due to its accessibility and the wealth of information it provides.
Aram Safrastyan +2 more
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Rust-Bio - a fast and safe bioinformatics library [PDF]
, 2015 We present Rust-Bio, the first general purpose bioinformatics library for the innovative Rust programming language. Rust-Bio leverages the unique combination of speed, memory safety and high-level syntax offered by Rust to provide a fast and safe set of ...
Köster, Johannes
core +5 more sources
Advances in Non-Coding RNA Sequencing
Non-Coding RNA, 2021 Non-coding RNAs (ncRNAs) comprise a set of abundant and functionally diverse RNA molecules. Since the discovery of the first ncRNA in the 1960s, ncRNAs have been shown to be involved in nearly all steps of the central dogma of molecular biology.
Julia Micheel +2 more
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Coronavirus Genomics and Bioinformatics Analysis [PDF]
Viruses, 2010 The drastic increase in the number of coronaviruses discovered and coronavirus genomes being sequenced have given us an unprecedented opportunity to perform genomics and bioinformatics analysis on this family of viruses. Coronaviruses possess the largest genomes (26.4 to 31.7 kb) among all known RNA viruses, with G + C contents varying from 32% to 43%.
Woo, PCY, Lau, SKP, Yuen, KY, Huang, Y
openaire +5 more sources
The Role of Non-Coding RNAs in the Human Placenta
Cells, 2022 Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs, and species, which has been broadly recognized since the human ENCODE project and several other genome projects.
Milena Žarković +3 more
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BMC Genomics, 2023 Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse +7 more
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SOBA: sequence ontology bioinformatics analysis [PDF]
Nucleic Acids Research, 2010 The advent of cheaper, faster sequencing technologies has pushed the task of sequence annotation from the exclusive domain of large-scale multi-national sequencing projects to that of research laboratories and small consortia. The bioinformatics burden placed on these laboratories, some with very little programming experience can be daunting ...
Moore, Barry +2 more
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Bioinformatic analysis of proteomics data [PDF]
BMC Systems Biology, 2014 Most biochemical reactions in a cell are regulated by highly specialized proteins, which are the prime mediators of the cellular phenotype. Therefore the identification, quantitation and characterization of all proteins in a cell are of utmost importance to understand the molecular processes that mediate cellular physiology.
Andreas Schmidt +2 more
openaire +3 more sources