Results 71 to 80 of about 1,093,449 (328)

Structure and Hierarchy of Influenza Virus Models Revealed by Reaction Network Analysis

open access: yesViruses, 2019
Influenza A virus is recognized today as one of the most challenging viruses that threatens both human and animal health worldwide. Understanding the control mechanisms of influenza infection and dynamics is crucial and could result in effective future ...
Stephan Peter   +8 more
doaj   +1 more source

Characterization of RNA content in individual phase-separated coacervate microdroplets

open access: yesNature Communications, 2022
Here, the authors demonstrate that single cell RNA sequencing technology can be leveraged to characterize RNA content of individual membrane-free condensates formed by liquid-liquid phase separation processes such as coacervation.
Damian Wollny   +12 more
doaj   +1 more source

The Small Size of the Small Scale Market: The Early-Stage Labor Market for Highly Skilled Nanotechnology Workers [PDF]

open access: yes, 2007
We examine the labor market for the highly trained in nanotechnology and the response of universities toward providing training. We draw comparisons with the labor market and university response in bioinformatics. The demand analysis is based on position
Grant C. Black   +2 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

A biophysical approach to large-scale protein-DNA binding data [PDF]

open access: yes, 2008
About this book * Cutting-edge genome analysis methods from leading bioinformaticians An accurate description of current scientific developments in the field of bioinformatics and computational implementation is presented by research of the BioSapiens ...
Manke, T., Roider, H., Vingron, M.
core   +1 more source

img2net: Automated network-based analysis of imaged phenotypes [PDF]

open access: yes, 2014
Automated analysis of imaged phenotypes enables fast and reproducible quantification of biologically relevant features. Despite recent developments, recordings of complex, networked structures, such as: leaf venation patterns, cytoskeletal structures, or
Breuer, David, Nikoloski, Zoran
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

RNA-protein interaction prediction without high-throughput data: An overview and benchmark of in silico tools

open access: yesComputational and Structural Biotechnology Journal
RNA-protein interactions (RPIs) are crucial for accurately operating various processes in and between organisms across kingdoms of life. Mutual detection of RPI partner molecules depends on distinct sequential, structural, or thermodynamic features ...
Sarah Krautwurst, Kevin Lamkiewicz
doaj   +1 more source

Comparative transcriptomics identifies candidate genes involved in the evolutionary transition from dehiscent to indehiscent fruits in Lepidium (Brassicaceae)

open access: yesBMC Plant Biology, 2022
Background Fruits are the seed-bearing structures of flowering plants and are highly diverse in terms of morphology, texture and maturation. Dehiscent fruits split open upon maturation to discharge their seeds while indehiscent fruits are dispersed as a ...
Lydia Gramzow   +6 more
doaj   +1 more source

Seasonality of endemic COVID-19

open access: yesmBio, 2023
Successive waves of infection by SARS-CoV-2 have left little doubt that this virus will transition to an endemic disease. Foreknowledge of when to expect seasonal surges is crucial for healthcare and public health decision-making.
Jeffrey P. Townsend   +8 more
doaj   +1 more source

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