Results 121 to 130 of about 16,187,582 (338)

Selected organophosphorus compounds with biological activity. Applications in medicine

open access: yes, 2016
The purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs have become popular in recent years.
Sebastian Demkowicz   +3 more
semanticscholar   +1 more source

Isolation, Identification, Modification, and Biological Analysis of extracts of A. Mexicana [PDF]

open access: yes, 2020
Argemone mexicana is a member of the Papaveraceae family of plants that has been used for centuries in traditional medicine by indigenous communities in Mexico and the United States.
Lefeber, Theodore   +3 more
core   +1 more source

Synthesis, characterization, and biological activity of a new class of dialkylphosphorylhydrazone derivatives of isatin

open access: yesQuímica Nova, 2014
Sixteen dialkylphosphorylhydrazones were synthesized by condensation of phosphorylhydrazines with substituted isatins. Products were characterized by FTIR, ¹H-NMR, 13C-NMR, and 31P-NMR.
Letícia Silotti Zampirolli   +6 more
doaj   +1 more source

Data-driven modeling of the olfactory neural codes and their dynamics in the insect antennal lobe [PDF]

open access: yes, 2013
Recordings from neurons in the insects' olfactory primary processing center, the antennal lobe (AL), reveal that the AL is able to process the input from chemical receptors into distinct neural activity patterns, called olfactory neural codes.
Kutz, J. Nathan   +2 more
core   +3 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Myricetin: biological activity related to human health

open access: yesApplied Biological Chemistry, 2016
Myricetin (3,5,7,3′,4′,5′-hexahydroxyflavone) is one of the natural flavonols from fruit, vegetable, tea, and medicinal plants. A great deal of attention has been paid to this compound owing to its various health-promoting effects.
Kwang-Su Park, Youhoon Chong, M. K. Kim
semanticscholar   +1 more source

Synthesis, antimycobacterial and antifungal evaluation of new 4-(furan-2-ylmethyl)-6-methylpyridazin-3(2H)-ones [PDF]

open access: yesJournal of the Serbian Chemical Society
This study reports the synthesis and evaluation of a series of new pyridazin-3-ones with furan moieties 5a–j and 6a–f, to test for their antimycobacterial and antifungal activities.
Karayavuz Burcu   +4 more
doaj   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

open access: yesFEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling   +4 more
wiley   +1 more source

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