Results 31 to 40 of about 16,187,582 (338)

Review of the synthesis and biological activity of thiazoles

Synthetic Communications, 2020
This study covers the literature documents available on the chemistry of preparation of thiazoles. Additionally, we cover the biological activities of certain thiazoles.
Sukinah H. Ali, A. R. Sayed
semanticscholar   +1 more source

A Mild Synthesis of New Aryl Vinyl Ethers and Diethyl 1-[(Alkyl)(cyano)methyl]vinylphosphonates via the Substitution of a 2,3-Difunctional Allyl Bromide

The Scientific World Journal, 2014
A novel class of aryl vinyl ethers 3 and diethyl 3-cyano-3-alkylprop-1-en-2-ylphosphonates 4 has been prepared, respectively, from coupling reaction of diethyl 1-(bromomethyl)-2-cyanovinylphosphonate 2 with phenols and Gilman reagents.
Asma Fray, Jihène Ben Kraïem, Aïcha Arfaoui, Hassen Amri   +3 more
doaj   +1 more source

Derivatives of Isoindoline, Synthesis and Biological Activity. II. Biological Activity of Derivatives of Isoindoline [PDF]

Kemija u Industriji, 2014
The derivatives of isoindolines show different biological activity in vitro and in vivo and it is hopeful that some of the compounds of this group will develop into new efficient drugs for different types of diseases in the future.
Sović, I., Karminski-Zamola, G.
doaj   +1 more source

Providing the basis for a patient-centred and effective screening for cancer-related fatigue (MERLIN study): design of a longitudinal observational study

BMJ Open, 2023
Introduction Cancer-related fatigue (CRF) is a frequent and burdensome sequela of cancer and cancer therapies. It can persist from months to years and has a substantial impact on patients’ quality of life and functioning.
Martina E Schmidt, Karen Steindorf, Bernhard Holzner, Patricia Blickle, Alexander Haussmann, Anne Katrin Berger   +5 more
doaj   +1 more source

Photoswitchable catalysis by a nanozyme mediated by a lightsensitive cofactor [PDF]

, 2017
The activity of a gold nanoparticle-based catalyst can be reversibly up- and down-regulated by light. Light is used to switch a small molecule between cis- and trans-isomers, which inhibits the catalytic activity of the nanoparticles to different extent.
Martin, Sergio Garcia, Neri, Simona, Pezzato, Cristian, Prins, Leonard Jan   +3 more
core   +2 more sources

Synthesis of New (E)-2-(1H-Indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles via Microwave-Assisted Knoevenagel Condensation

Journal of Chemistry, 2017
Given the broad spectrum of biological uses of heteroaryl-acrylonitrile derivatives, it is necessary to find simple methods to synthesize and diversify this family of compounds.
Adriana V. Treuer, Pedro De-La-Torre, Margarita I. Gutiérrez   +2 more
doaj   +1 more source

Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes

Genome Medicine, 2017
Background Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone.
Leif Väremo, Tora Ida Henriksen, Camilla Scheele, Christa Broholm, Maria Pedersen, Mathias Uhlén, Bente Klarlund Pedersen, Jens Nielsen   +7 more
doaj   +1 more source

Biological Activity of Hexaazaisowurtzitane Derivatives

Molecules, 2023
Biologically active compounds of natural or synthetic origin have a complex structure and generally contain various structural groups among which polycyclic cage amines are found.
Daria A. Kulagina, Sergey V. Sysolyatin, Svetlana G. Krylova, Elena A. Kiseleva, Tatiana N. Povetyeva, Elena P. Zueva, Valeria V. Eremina, Natalia A. Alekseeva, Svetlana V. Strokova, Nikolai I. Suslov, Vadim V. Zhdanov   +10 more
doaj   +1 more source

Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]

, 2014
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh, Ausar, Salvador F, Brookes, Roger H, Dockrell, Hazel M, Ha, Yukyung, Hakimi, Jalil, Hasija, Manvi, Rahman, Nausheen, Smith, Steven G, Todryk, Stephen M   +9 more
core   +1 more source

Biological Activity of Ionic Liquids and Their Application in Pharmaceutics and Medicine.

Chemical Reviews, 2017
Ionic liquids are remarkable chemical compounds, which find applications in many areas of modern science. Because of their highly tunable nature and exceptional properties, ionic liquids have become essential players in the fields of synthesis and ...
K. S. Egorova, E. Gordeev, V. Ananikov
semanticscholar   +1 more source