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Biological Age Predictors [PDF]

open access: yesEBioMedicine, 2017
The search for reliable indicators of biological age, rather than chronological age, has been ongoing for over three decades, and until recently, largely without success. Advances in the fields of molecular biology have increased the variety of potential
Juulia Jylhävä   +2 more
doaj   +3 more sources

Heat Shock Factor 1 as a Prognostic and Diagnostic Biomarker of Gastric Cancer

open access: yesBiomedicines, 2021
Identification of effective prognostic and diagnostic biomarkers is needed to improve the diagnosis and treatment of gastric cancer. Early detection of gastric cancer through diagnostic markers can help establish effective treatments. Heat shock factor 1
Woong Kim, Seok-Jun Kim
doaj   +1 more source

The LIM domain protein nTRIP6 modulates the dynamics of myogenic differentiation

open access: yesScientific Reports, 2021
The process of myogenesis which operates during skeletal muscle regeneration involves the activation of muscle stem cells, the so-called satellite cells.
Tannaz Norizadeh Abbariki   +8 more
doaj   +1 more source

Inhibition of emotions in healthy aging: age‐related differences in brain network connectivity

open access: yesBrain and Behavior, 2021
Introduction Successful inhibition of distracting emotions is important for preserving well‐being and daily functioning. There is conflicting evidence regarding the impact of healthy aging on emotional inhibition, and possible age‐related alterations in ...
Ina S. Almdahl   +4 more
doaj   +1 more source

Structure-based insights into evolution of rhodopsins

open access: yesCommunications Biology, 2021
Zabelskii et al. present a structural and functional analysis of the lightdriven proton pump LR (Mac) from the fungus Leptosphaeria maculans. Their findings indicate that the archaeal ancestry of eukaryotic type 1 rhodopsins, and that the archaeal host ...
Dmitrii Zabelskii   +21 more
doaj   +1 more source

Frailty and Biological Age [PDF]

open access: yesAnnals of Geriatric Medicine and Research, 2021
A reliable model of biological age is instrumental in the field of geriatrics and gerontology. This model should account for the heterogeneity and plasticity of aging and also accurately predict aging-related adverse outcomes. Epigenetic age models are based on DNA methylation levels at selected genomic sites and can be significant predictors of ...
Lixin Ji   +2 more
openaire   +3 more sources

Correlation of dental and chronological maturity in girls and boys aged 7 to 14 years [PDF]

open access: yesStomatološki glasnik Srbije, 2005
The aim of the study was to assess correlation level of dental and chronological maturity related to gender in a group of children of our population. Material and method: Total number of 320 girls and boys, 7 to 14 years old, participated in the study ...
Nikolić Zorana   +2 more
doaj   +1 more source

Crystal Structure of a Proteolytic Fragment of the Sensor Histidine Kinase NarQ

open access: yesCrystals, 2020
Two-component signaling systems (TCSs) are a large and important class of sensory systems in bacteria, archaea, and some eukaryotes, yet their mechanism of action is still not fully understood from the structural point of view.
Ivan Gushchin   +4 more
doaj   +1 more source

Raman Scattering: From Structural Biology to Medical Applications

open access: yesCrystals, 2020
This is a review of relevant Raman spectroscopy (RS) techniques and their use in structural biology, biophysics, cells, and tissues imaging towards development of various medical diagnostic tools, drug design, and other medical applications.
Alexey V. Vlasov   +18 more
doaj   +1 more source

Molecular mechanism of light-driven sodium pumping

open access: yesNature Communications, 2020
The Na+-pumping KR2 rhodopsin from Krokinobacter eikastus is a light-driven non-proton cation pump whose mechanism of pumping remains to be understood. Here authors solved crystal structures of the O-intermediate state of the pentameric form of KR2 and ...
Kirill Kovalev   +23 more
doaj   +1 more source

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