Results 31 to 40 of about 3,238,552 (285)

Menopause accelerates biological aging [PDF]

open access: yesProceedings of the National Academy of Sciences, 2016
Significance Within an evolutionary framework, aging and reproduction are intrinsically linked. Although both laboratory and epidemiological studies have observed associations between the timing of reproductive senescence and longevity, it is not yet known whether differences in the age of menopause are reflected in biomarkers of ...
Levine, Morgan E   +18 more
openaire   +5 more sources

Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs

open access: yesBiomedicines, 2023
Background: Kivach Clinic has developed a special medical spa program to prevent aging-related conditions in metabolic, cardio-vascular, and neurological states. Spa programs modify diet, physical activity, and lymphatic drainage, as it deteriorates with
Fedor I. Isaev   +2 more
doaj   +1 more source

Monte Carlo Simulation of Age-Dependent Host-Parasite Relations

open access: yes, 2007
The death of a biological population is an extreme event which we investigate here for a host-parasitoid system. Our simulations using the Penna ageing model show how biological evolution can ``teach'' the parasitoids to avoid extinction by waiting for ...
Ana Proykova   +7 more
core   +2 more sources

Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions

open access: yesNeurobiology of Disease, 2005
We have shown that over-expression of human tau (0N3R) in Drosophila larval motor neurons causes significant morphological and functional disruption to the neuromuscular junctions (NMJs).
Francis C. Chee   +6 more
doaj   +1 more source

Accelerated aging and psychological age of an individual as risk factors for COVID-19 complications

open access: yesНаука и инновации в медицине, 2021
Objectives to study the effect of psychological age on the risk of severe forms of Covid-19 in adults. Material and methods. Research method: natural experiment. The 1st measurement: indicators of biopsychological age - mid-2020, the 2nd measurement:
Tatyana N. Berezina   +3 more
doaj   +1 more source

Efficient Monte Carlo Simulation of Biological Aging

open access: yes, 1995
A bit-string model of biological life-histories is parallelized, with hundreds of millions of individuals. It gives the desired drastic decay of survival probabilities with increasing age for 32 age intervals.Comment: PostScript file to appear in Int.J ...
Penna, T. J. P., Stauffer, D.
core   +1 more source

Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy. [PDF]

open access: yes, 2019
MotivationMultiple biological clocks govern a healthy pregnancy. These biological mechanisms produce immunologic, metabolomic, proteomic, genomic and microbiomic adaptations during the course of pregnancy.
Agard, Bruno   +42 more
core   +3 more sources

A whole lifespan mouse multi-tissue DNA methylation clock

open access: yeseLife, 2018
Age predictors based on DNA methylation levels at a small set of CpG sites, DNAm clocks, have been developed for humans and extended to several other species.
Margarita V Meer   +3 more
doaj   +1 more source

The use of urinary proteomics in the assessment of suitability of mouse models for ageing [PDF]

open access: yes, 2017
Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, understanding its underlying molecular mechanisms can ...
Bajwa, Seerat   +17 more
core   +3 more sources

Dendritic Cell Immunotherapy for Solid Tumors: Advances in Translational Research and Clinical Application

open access: yesCurrent Issues in Molecular Biology
Dendritic cells (DCs) are critical antigen-presenting cells that orchestrate the interface between innate and adaptive immunity, making them attractive approaches for cancer immunotherapy.
Mi Eun Kim, Jun Sik Lee
doaj   +1 more source

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