Results 71 to 80 of about 911,648 (354)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Use of Multiflora Bee Pollen as a Flor Velum Yeast Growth Activator in Biological Aging Wines
Molecules, 2019 Flor velum yeast growth activators during biological aging are currently unknown. In this sense, this research focuses on the use of bee pollen as a flor velum activator. Bee pollen influence on viable yeast development, surface hydrophobicity, and yeast
Pau Sancho-Galán +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Бюллетень сибирской медицины, 2007 The purpose of the investigation is studying aging rates and antioxidative status of workers the influence of industrial xenobiotics. 833 workers are examined for biological age, activities of antioxidative ferments, concentration of the peroxidation ...
S. A. Maksimov
doaj +1 more source
Materials Research Express, 2021 Objective . The study aimed to investigate the physicochemical properties of titanium surfaces with different morphologies stored in a saline solution and their effects on osteoblast behavior. Methods .
Kai-Ming Tang +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Time for a Systems Biological Approach to Cognitive Aging?—A Critical Review
Frontiers in Aging Neuroscience, 2020 The underlying premise of current theories of cognitive decline with age tend to be primarily cognitive or biological explanations, with relatively few theories adequately integrating both aspects.
Deena Ebaid, Sheila G. Crewther
doaj +1 more source
A microRNA feedback loop regulates global microRNA abundance during aging [PDF]
, 2017 Expression levels of many microRNAs (miRNAs) change during aging, notably declining globally in a number of organisms and tissues across taxa. However, little is known about the mechanisms or the biological relevance for this change.
de Lencastre, Alexandre +3 more
core +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An Unusual Antagonistic Pleiotropy in the Penna Model for Biological Ageing
, 2001 We combine the Penna Model for biological aging, which is based on the mutation-accumulation theory, with a sort of antagonistic pleiotropy. We show that depending on how the pleiotropy is introduced, it is possible to reproduce both the humans mortality,
Bernardes +15 more
core +1 more source