Results 61 to 70 of about 911,648 (354)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Frontiers in Public Health, 2023 PurposeOne possible way to quantify each individual's response or damage from ionizing radiation is to estimate their accelerated biological age following exposure.
Nathan A. Ruprecht +7 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Through the Lens of Age: Using Dog Photographs to Uncover Welfare and Stress
PetsThis study evaluated the potential of using dogs’ apparent age, judged from photographs, as a non-invasive tool for assessing their welfare. Traditional welfare assessment methods often rely on behavioral and physiological indicators, which can be ...
Luisa Mascarenhas Ladeia Dutra +2 more
doaj +1 more source
Investigation of temperature dependence of development and aging [PDF]
, 1969 Temperature dependence of maturation and metabolic rates in insects, and the failure of vital processes during development were investigated. The paper presented advances the general hypothesis that aging in biological systems is a consequence of the ...
Sacher, G. A.
core +1 more source
Sympatric speciation in an age-structured population living on a lattice [PDF]
, 2004 A square lattice is introduced into the Penna model for biological aging in order to study the evolution of diploid sexual populations under certain conditions when one single locus in the individual's genome is considered as identifier of species.
A. O. Sousa +8 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Frontiers in NutritionBackgroundThe rising intake of ultra-processed foods (UPFs) has been linked to adverse health outcomes, yet its impact on aging acceleration remains unclear.ObjectiveThis study aimed to examine the association between the percentage of total daily ...
Weiliang Kong +3 more
doaj +1 more source
Achieving and Maintaining Cognitive Vitality With Aging [PDF]
, 2001 This report contains the summary results of a workshop held at Canyon Ranch Health Resort in Tucson, Arizona. Physicians and scientists shed light on the process of cognitive aging.
Howard Fillit, Robert N. Butler
core
The aging-disease false dichotomy: understanding senescence as pathology [PDF]
, 2015 From a biological perspective aging (senescence) appears to be a form of complex disease syndrome, though this is not the traditional view. This essay aims to foster a realistic understanding of aging by scrutinizing ideas old and new.
Gems, D
core +1 more source