Results 61 to 70 of about 2,895,252 (212)
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
The reports were prepared with the assistance of the Kansas Department on Aging.; Created in 1977 by the Kansas Act on the Aging, the ACA is represents different geographical, social and ethnic groups, with at least half its members being 60 years of age
Kansas Advisory Council on Aging.
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Aging and coronary artery calcification: a Mendelian randomization study
Introduction Coronary artery calcification (CAC) is a recognized marker of atherosclerosis and cardiovascular disease (CVD) risk. While CAC is closely linked to aging, its potential as a marker of biological aging remains uncertain. Telomere length (TL),
Mateusz Lejawa +8 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
[Coalition for Aging LGBT Initial Board Exploratory Meeting Document]
Initial Board Exploratory Meeting documents from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
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ObjectiveThis study aimed to investigate the association of pregnancy history with biological age (BA) and BA acceleration, and to explore joint effect with lifestyle factors.MethodsThis cross-sectional study used data from the UK Biobank, a population ...
Yuting Yao +7 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
[Coalition for Aging LGBT Board of Directors Meeting Agenda]
Board of Directors Meeting agenda document from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
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BackgroundPrevious studies have shown that dietary patterns are associated with health outcomes in Chinese middle-aged and older adults. However, whether dietary patterns are associated with Klemera-Doubal biological age (KDM-BA) and physiological ...
Xu Zhu +4 more
doaj +1 more source

