Results 161 to 170 of about 5,783,416 (253)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1950
, 1951 Annual report of the Marine Biological Laboratory in Woods Hole. 1950.
Marine Biological Laboratory (Woods Hole MA)
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1941
, 1942 Annual report of the Marine Biological Laboratory in Woods Hole. 1941.
Marine Biological Laboratory (Woods Hole MA)
core
MethAgingDB: a comprehensive DNA methylation database for aging biology
Scientific DataAccurately quantifying biological age is crucial for understanding the mechanisms of aging and developing effective interventions. Molecular aging clocks, particularly epigenetic clocks that use DNA methylation data to estimate biological age, have ...
Siyu Li +4 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1980
, 1981 Annual report of the Marine Biological Laboratory in Woods Hole. 1980.
Marine Biological Laboratory (Woods Hole MA)
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1939
, 1940 Annual report of the Marine Biological Laboratory in Woods Hole. 1939.
Marine Biological Laboratory (Woods Hole MA)
core
Bioinformatics and Biology InsightsEpigenetic age is a biological age estimate based on nuclear DNA methylation patterns. Epigenetic clocks measure biological age by analyzing predictable changes in DNA methylation sites associated with aging.
Stanislav Rayevskiy +4 more
doaj +1 more source