Results 51 to 60 of about 2,696,596 (307)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Evaluation of Stability, Inactivation, and Disinfection Effectiveness of Mpox Virus

open access: yesViruses
Background: Mpox virus (MPXV) infections have increased in many countries since May 2022, increasing demand for diagnostic tests and research on the virus.
Yuwei Li   +12 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Identification of Critical Amino Acids of Coxsackievirus A10 Associated with Cell Tropism and Viral RNA Release during Uncoating

open access: yesViruses, 2023
Coxsackievirus A10 (CV-A10) is a prevailing causative agent of hand–foot–mouth disease, necessitating the isolation and adaptation of appropriate strains in cells allowed for human vaccine development.
Jie Pei   +8 more
doaj   +1 more source

Comparing low rate copper formulations against Phythophthora infestans in potatoes [PDF]

open access: yes, 2009
Between Dutch organic growers the late blight problems lead to discussions in which a temporary registration of copper products is also suggested. Some growers do not want any pesticides at all, while others see that biological potatoes from abroad are ...
Bus, C.B.
core   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yesFEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic   +2 more
wiley   +1 more source

The Immune System [PDF]

open access: yes, 1995
Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut   +1 more
core   +1 more source

Identification of putative steroid receptor antagonists in bottled water : combining bioassays and high-resolution mass spectrometry [PDF]

open access: yes, 2013
Endocrine disrupting chemicals (EDCs) are man-made compounds interfering with hormone signaling and thereby adversely affecting human health. Recent reports provide evidence for the presence of EDCs in commercially available bottled water, including ...
Oehlmann, Jörg   +3 more
core   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Research progress on the influence of ligands on the stability of albumin

open access: yesZhongguo shuxue zazhi
It is necessary to improve the stability of human serum albumin in response to the complex temperature, light and other conditions during the manufacture and storage.
Lieqing YANG   +6 more
doaj   +1 more source

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