Transcriptome analysis of cortical tissue reveals shared sets of downregulated genes in autism and schizophrenia. [PDF]
Autism (AUT), schizophrenia (SCZ) and bipolar disorder (BPD) are three highly heritable neuropsychiatric conditions. Clinical similarities and genetic overlap between the three disorders have been reported; however, the causes and the downstream effects ...
Arking, DE +3 more
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In this Perspective, we highlight the growing need for trauma-informed practices as researchers increasingly work across disciplines to study the effects of childhood trauma.
Mica Komarnyckyj +2 more
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Schizophrenia, social practices and cultural values: A conceptual introduction [PDF]
Schizophrenia is usually described as a fragmentation of subjective experience and the impossibility to engage in meaningful cultural and intersubjective practices. Although the term schizophrenia is less than 100 years old, madness is generally believed
Gonçalves, J. +2 more
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Practitioner review: Borderline personality disorder in adolescence: Recent conceptualization, intervention, and implications for clinical practice [PDF]
The past decade has seen an unprecedented increase in research activity on personality disorders in adolescents. The increase in research activity, in addition to major nosological systems legitimizing the diagnosis of borderline personality disorder ...
Fonagy, P, Sharp, C
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Psychiatry outside the framework of empiricism
Science is interested in whatever that is empirical and objective. Any claim that cannot be objectively demonstrated has no place in science, because the subject does not deviate from the role, which it has set out to play in the life of mankind ...
Celestine Okorome Mume
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Correction to: Comparing Serum Zinc and Cortisol Concentrations in Patients with Major Depressive Disorder Treated with Fluoxetine and Cognitive-Behavioral Therapy: A Randomized Clinical Trial [PDF]
Mehrdad Jalalian1, Mehdi Pourasghar2, Ahmad Majd3, Hossein Ghalehnoei4, Zahra Kianmehr5 1 PhD Student in Biochemistry, Department of Biochemistry, Faculty of Biological Sciences, North Tehran Branch, Islamic Azad University, Tehran, Iran 2 Associate
Mehrdad Jalalian +4 more
doaj
Association between a longer duration of illness, age and lower frontal lobe grey matter volume in schizophrenia [PDF]
The frontal lobe has an extended maturation period and may be vulnerable to the long-term effects of schizophrenia. We tested this hypothesis by studying the relationship between duration of illness (DoI), grey matter (GM) and cerebro-spinal fluid (CSF ...
Abe +67 more
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How can we obtain truly translational mouse models to improve clinical outcomes in schizophrenia?
Steven J. Clapcote
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Using transcranial direct-current stimulation (tDCS) to understand cognitive processing [PDF]
Noninvasive brain stimulation methods are becoming increasingly common tools in the kit of the cognitive scientist. In particular, transcranial direct-current stimulation (tDCS) is showing great promise as a tool to causally manipulate the brain and ...
Cosman, Josh D. +3 more
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Biological psychiatry in perspective [PDF]
Biological psychiatry is a technical term that denotes physiological and biochemical approaches to psychiatric aetiology and, despite the usual wider meaning of the word biological, excludes psychosocial approaches. 'Biological' causes of severe psychiatric disorder have been suspected from the earliest times, and in some periods an excessive focus ...
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