Results 11 to 20 of about 3,349,315 (392)
Rhinology, 2023 Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a significant impact on the quality of life (QoL). It is typically characterized by a type 2 inflammatory reaction and by comorbidities such as asthma, allergies and ...
W. Fokkens +18 more
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Assessing developability early in the discovery process for novel biologics
mAbs, 2023 Beyond potency, a good developability profile is a key attribute of a biological drug. Selecting and screening for such attributes early in the drug development process can save resources and avoid costly late-stage failures.
M. Fernández-Quintero +15 more
semanticscholar +1 more source
Biologics and airway remodeling in severe asthma
Allergy. European Journal of Allergy and Clinical Immunology, 2022 Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in part can become irreversible to conventional therapies, defining the concept of airway remodeling.
G. Varricchi +9 more
semanticscholar +1 more source
Risk of Paradoxical Eczema in Patients Receiving Biologics for Psoriasis
JAMA dermatology, 2023 This cohort study examines which biologic drug classes and factors are associated with risk of paradoxical eczema in patients with psoriasis treated with biologics.
A. Al-Janabi +9 more
semanticscholar +1 more source
American Journal of Gastroenterology, 2021 Therapeutic drug monitoring (TDM) of biologics is a rapidly evolving field. We aimed to provide a consensus statement regarding the clinical utility of TDM for biologics in inflammatory bowel disease (IBD). A modified Delphi method was applied to develop
A. Cheifetz +11 more
semanticscholar +1 more source
The impact of COVID‐19 infection on psoriatic patients treated with biologics: an Italian experience
Clincal and Experimental Dermatology, 2022 Title: The impact of COVID-19 infection on psoriatic patients treated with biologics: an Italian experience.
A. Ruggiero +7 more
semanticscholar +1 more source
Biological Crystallization [PDF]
Crystals, 2015 “Biological Crystallization” is today a very wide topic that includes biomineralization, but also the laboratory crystallization of biological compounds such as macromolecules, carbohydrates or lipids, and the synthesis and fabrication of biomimetic materials by different routes [...]
Jaime Gómez-Morales +2 more
openaire +6 more sources
Thermal stabilization of diverse biologics using reversible hydrogels
Science Advances, 2022 Improving the thermal stability of biologics, including vaccines, is critical to reduce the economic costs and health risks associated with the cold chain. Here, we designed a versatile, safe, and easy-to-use reversible PEG-based hydrogel platform formed
B. Marco-Dufort +9 more
semanticscholar +1 more source
Gastroenterology, 2020 BACKGROUND Pregnant women with inflammatory bowel disease (IBD) may require biologic or thiopurine therapy to control disease activity. Lack of safety data has led to therapy discontinuation during pregnancy with health repercussions to mother and child.
U. Mahadevan +8 more
semanticscholar +1 more source
Aspiration-assisted bioprinting for precise positioning of biologics
Science Advances, 2020 Aspiration-assisted bioprinting enables precise positioning of viscoelastic spheroids in both scaffold-based and free manner. Three-dimensional (3D) bioprinting is an appealing approach for building tissues; however, bioprinting of mini-tissue blocks (i ...
Buğra Ayan +6 more
semanticscholar +1 more source