Bioluminescent imaging: new opportunities [PDF]
Modern biomedical research technologies actively use bioimaging for studying cells, tissues and whole organisms. Multicolor bioimaging is applied when simultaneous observation of different events at the molecular and cellular level is needed. Bioluminescent imaging methods are the most sensitive, however, their use for multicolor labeling is ...
ZM Osipova, AS Shcheglov, IV Yampolsky
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Molecular Imaging Using Bioluminescence [PDF]
Recent progress in the development of non-invasive imaging technologies continues to strengthen the role of molecular imaging in biological research. Small animal imaging with bioluminescence has been validated recently in a variety of research models and have been shown to provide continuous quantitative monitoring of the location(s), magnitude, and ...
Byeong Il Lee, Jung-Joon Min
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Pea (Pisum sativum L.) is an important leguminous plant worldwide, in which pests trigger significant damage every year. One of the most important pest is pea weevil (Bruchus pisorum, L) which causes covert damage in crops.
Sándor Keszthelyi +4 more
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Novel locally active estrogens accelerate cutaneous wound healing-part 2 [PDF]
Estrogen deprivation is associated with delayed healing, while estrogen replacement therapy (ERT) accelerates acute wound healing and protects against development of chronic wounds.
Bartoli, Gabriele +12 more
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The in vitro and in vivo effects of constitutive light expression on a bioluminescent strain of the mouse enteropathogen Citrobacter rodentium [PDF]
Bioluminescent reporter genes, such as those from fireflies and bacteria, let researchers use light production as a non-invasive and non-destructive surrogate measure of microbial numbers in a wide variety of environments.
Hannah M. Read +8 more
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U-SPECT-BioFluo: an integrated radionuclide, bioluminescence, and fluorescence imaging platform [PDF]
Background: In vivo bioluminescence, fluorescence, and single-photon emission computed tomography (SPECT) imaging provide complementary information about biological processes.
Beekman, Freek J +7 more
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Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model. [PDF]
Inhibitors of BRAFV600E kinase are currently under investigations in preclinical and clinical studies involving BRAFV600E glioma. Studies demonstrated clinical response to such individualized therapy in the majority of patients whereas in some patients ...
Berger, Mitchel S +12 more
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Red-Shifted Aequorin Variants Incorporating Non-Canonical Amino Acids: Applications in In Vivo Imaging. [PDF]
The increased importance of in vivo diagnostics has posed new demands for imaging technologies. In that regard, there is a need for imaging molecules capable of expanding the applications of current state-of-the-art imaging in vivo diagnostics.
Kristen M Grinstead +7 more
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Immunogenicity of targeted lentivectors [PDF]
To increase the safety and possibly efficacy of HIV-1 derived lentivectors (LVs) as an anti-cancer vaccine, we recently developed the Nanobody (Nb) display technology to target LVs to antigen presenting cells (APCs).
Adotévi +67 more
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Mutation of Arabidopsis SPLICEOSOMAL TIMEKEEPER LOCUS1 Causes Circadian Clock Defects [PDF]
The circadian clock plays a crucial role in coordinating plant metabolic and physiological functions with predictable environmental variables, such as dusk and dawn, while also modulating responses to biotic and abiotic challenges.
Brown, John WS +5 more
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