Results 71 to 80 of about 63,349 (279)

Fast in vivo bioluminescence tomography using a novel pure optical imaging technique [PDF]

Journal of Innovative Optical Health Sciences, 2017
Bioluminescence tomography (BLT) is a novel optical molecular imaging technique that advanced the conventional planar bioluminescence imaging (BLI) into a quantifiable three-dimensional (3D) approach in preclinical living animal studies in oncology.
Shuang Zhang, Chengcai Leng, Hongbo Liu, Kun Wang, Jie Tian   +4 more
doaj   +1 more source

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. [PDF]

, 2014
Ewing sarcoma is the second-most-common bone cancer in children. Driven by an oncogenic chromosomal translocation that results in the expression of an aberrant transcription factor, EWS/FLI, the disease is typically aggressive and micrometastatic upon ...
Beckerle, Mary C, Chaturvedi, Aashi, Grossmann, Allie H, Hoffman, Laura M, Jensen, Christopher C, Lessnick, Stephen L, Lin, Yi-Chun, Randall, R Lor, Welm, Alana L   +8 more
core   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Orthotopic hepatocellular carcinoma: molecular imaging-monitored intratumoral hyperthermia-enhanced direct oncolytic virotherapy

International Journal of Hyperthermia, 2019
Objective: To validate the feasibility of molecular imaging-monitored intratumoral radiofrequency hyperthermia (RFH) enhanced direct oncolytic virotherapy for hepatocellular carcinoma (HCC).
Jingjing Song, Feng Zhang, Jiansong Ji, Minjiang Chen, Qiang Li, Qiaoyou Weng, Shannon Gu, Matthew J. Kogut, Xiaoming Yang   +8 more
doaj   +1 more source

Evaluation of laser bacterial anti-fouling of transparent nanocrystalline yttria-stabilized-zirconia cranial implant. [PDF]

, 2016
Background and objectiveThe development and feasibility of a novel nanocrystalline yttria-stabilized-zirconia (nc-YSZ) cranial implant has been recently established.
Aguilar, Guillermo, Damestani, Yasaman, De Howitt, Natalie, Garay, Javier E, Halaney, David L   +4 more
core   +1 more source

Semi-automated Image Processing for Preclinical Bioluminescent Imaging [PDF]

Journal of Applied Bioinformatics & Computational Biology, 2015
Bioluminescent imaging is a valuable noninvasive technique for investigating tumor dynamics and specific biological molecular events in living animals to better understand the effects of human disease in animal models. The purpose of this study was to develop and test a strategy behind automated methods for bioluminescence image processing from the ...
Nikolai V, Slavine, Roderick W, McColl
openaire   +2 more sources

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Current advances in the development of bioluminescent probes toward spatiotemporal trans-scale imaging

Biophysics and Physicobiology
Bioluminescence imaging has recently attracted great attention as a highly sensitive and non-invasive analytical method. However, weak signal and low chemical stability of the luciferin are conventional drawbacks of bioluminescence imaging.
Akihiro Sakama, Mariko Orioka, Yuki Hiruta   +2 more
doaj   +1 more source

Use of a highly sensitive two-dimensional luminescence imaging system to monitor endogenous bioluminescence in plant leaves

BMC Plant Biology, 2004
Background All living organisms emit spontaneous low-level bioluminescence, which can be increased in response to stress. Methods for imaging this ultra-weak luminescence have previously been limited by the sensitivity of the detection systems used ...
Flor-Henry Michel, McCabe Tulene C, de Bruxelles Guy L, Roberts Michael R   +3 more
doaj   +1 more source

Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2

Scientific Reports, 2022
The bacterial bioluminescence system enables the generation of light by living cells without the requirement of an external luciferin. Due to the relatively low light emission, many applications of bioluminescence imaging would benefit from an increase ...
Carola Gregor
doaj   +1 more source