Results 131 to 140 of about 7,863 (172)

A Modular Platform for Quantitative Two-Color Bioluminescence Combining NanoLuc and Red-Shifted NanoPrism Luciferases. [PDF]

ACS Chem Biol
Porter K, Killoran M, Hurst R, Klein M, De Bakshi D, Esmatpour R, Encell LP, Gama-Franceschi F, Bessetti J, Riching KM, Machleidt T, Mezzanotte L, Friedman Ohana R.   +12 more
europepmc   +1 more source

Semisynthetic, Multicolor Probes for Bioluminescence Imaging. [PDF]

ACS Omega
Tran S, Usavage K, Halbers LP, Choplick C, Helton G, Young B, Prescher JA, Rathbun CM.   +7 more
europepmc   +1 more source

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The Activity of the Insulin Receptor Assessed by Bioluminescence Resonance Energy Transfer

Annals of the New York Academy of Sciences, 2002
Abstract:This work describes a new assay, based on the bioluminescence resonance energy transfer (BRET) methodology, to monitor the activation state of the insulin receptor.
Tarik Issad
exaly   +3 more sources

Bioluminescence Resonance Energy Transfer for Global DNA Methylation Quantification

2022
Global hypomethylation of genomic DNA is associated with genomic instability and carcinogenic processes. The loss of DNA methylation has been reported in several cancers; therefore, global methylation levels have been considered as biomarkers for cancer diagnosis.
Natsumi, Taka, Yuji, Baba, Yuka, Iwasaki, Wataru, Yoshida   +3 more
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A Bioluminescence Resonance Energy Transfer–Based Reporter System: Characterization and Applications

The CRISPR Journal, 2021
Genome editing strategies and DNA repair research need powerful analytical tools. We generated a bioluminescence resonance energy transfer (BRET)-based reporter for the quantification of indel frequencies induced by DNA repair. The BRET reporter, expressed as a single molecule, consists of a mutated Renilla ...
Tobias, Wimmer, Dileep, Bonthu, Vincent, Moeschl, Philip, Kleekamp, Christian, Thiel, Lyubomyr, Lytvynchuk, Matthew, Ellinwood, Knut, Stieger   +7 more
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Application of Bioluminescence Resonance Energy Transfer (BRET) for Biomolecular Interaction Studies

ChemBioChem, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Friedrich W Herberg
exaly   +3 more sources

Bioluminescence and Bioluminescense Resonance Energy Transfer Assays in Microfluidics

2013
Bioluminescence reaction is a light-emitting chemical reaction involving a photoactive substrate (luciferin), an enzyme (luciferase), and cofactor(s). During the bioluminescence reaction, the substrate is catalyzed with the enzyme resulting in emission of a photon with a certain wavelength.
Murat Gel, Nam Le, Alisha Anderson, Stephen Trowell, Yonggang Zhu   +4 more
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The New Era of Bioluminescence Resonance Energy Transfer Technology

Current Pharmaceutical Biotechnology, 2011
Bioluminescence resonance energy transfer (BRET) assay is a comparatively new cell-based assay technology that is assuming more prominent roles in the field of studying protein-protein interactions, protein dimerization and signal transduction. In the last few years BRET related research has gained significant momentum in terms of adding versatility in
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Bioluminescence resonance energy transfer‐based detection of acetyl‐CoA

The FASEB Journal, 2022
CoA metabolites play a critical role in the epigenetic regulation of gene expression. Of particular significance is acetyl‐CoA, a primary metabolite used by histone acetyltransferases to modify histone tails and therefore control chromatin state. In cancer cells, the dysregulation of acetyl‐CoA can lead to the aberrant expression of genes controlling ...
Whitney Lieberman, Isita Jhulki, Jordan Meier   +2 more
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Bioluminescence Resonance Energy Transfer Nanoprobes for Imaging

IEEE Journal of Selected Topics in Quantum Electronics, 2014
Despite the advantages of bioluminescence (BL) over fluorescence, its potential use for in vivo imaging has been hindered because BL signals emitted at short wavelengths are strongly attenuated by light scattering and absorption under in vivo conditions.
openaire   +1 more source