Results 91 to 100 of about 12,382 (217)
Biochemistry and Molecular Biology Education, EarlyView.ABSTRACT Low‐cost experiential modules are critical for democratizing biotechnology education, yet most undergraduates lack hands‐on experience with continuous‐culture bioreactor operations, which are fundamental to industrial bioprocessing. This study employed design‐based research across two iterative cycles (Fall 2024, n = 8; Fall 2025, n = 11) to ...
Russell K. Pirlo +2 more
wiley +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
BMEMat, EarlyView.The mechanism of HA‐DS@PLGA nanoparticles co‐delivering DOX and SNAP (an NO donor) to suppress tumor growth, remodel the tumor microenvironment, and enhance antitumor immune responses for effective combinatorial cancer therapy. Abstract Cancer therapeutic efficacy is significantly influenced by tumor immunosuppressive environment possibly induced by ...
Xingzhou Peng +10 more
wiley +1 more source
BMEMat, EarlyView.To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv +3 more
wiley +1 more source
Online Resources For Teaching Biomanufacturing
, 2020 This video is part of the AC2 Biomanufacturing Workshop 1- Overview and Bacterial Systems that was held by AC2 Bio-Link Regional Center and InnovATEBIO National Center.
core +1 more source
Additive biomanufacturing of scaffolds for breast reconstruction
, 2019 Limitations for the current clinical treatment strategies for breast reconstruction have prompted researchers and bioengineers to develop unique techniques based on tissue engineering and regenerative medicine (TE&RM) principles.
Schmutz, B +4 more
core +1 more source
Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses
Biotechnology Progress, EarlyView.Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing +2 more
wiley +1 more source
, 2020 This 5-page syllabus provides an overview of the Biotech 262: Biomanufacturing course taught at Kennedy King College. This course introduces students to concepts of the production of biopharmaceutical products using bacteria ...
core +1 more source
Regenerative perfusion bioreactor for biologics production with lower COGs
Biotechnology Progress, EarlyView.Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne +5 more
wiley +1 more source
Enzymatic Electrosynthesis for Sustainable CO2 Conversion: Advancing Circular Carbon Economy
Carbon Energy, EarlyView.Enzymatic electrosynthesis (EES) offers molecular precision in synthesizing value‐added products from CO2. We highlight its distinct edge over alternative enzyme‐hybrid systems and analyze electron transfer pathways. Key strategies to overcome electron transfer bottlenecks and expand product diversity are addressed, and also data‐driven approaches for ...
Yan Xie +7 more
wiley +1 more source