Results 1 to 10 of about 2,936,789 (384)
Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core +3 more sources
Background Weight loss therapy is becoming more and more important, and two classes of molecules, namely amylin receptor and GLP-1 receptor agonists, have shown promise in this regard.
Anna Thorsø Larsen +4 more
doaj +1 more source
The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting [PDF]
The 2018 FARA Biomarker Meeting highlighted the current state of development of biomarkers for Friedreich's ataxia. A mass spectroscopy assay to sensitively measure mature frataxin (reduction of which is the root cause of disease) is being developed ...
Blair, Ian A. +8 more
core +1 more source
Biomarkers in emergency medicine [PDF]
Researchers navigate the ocean of biomarkers searching for proper targets and optimal utilization of them. Emergency medicine builds up the front line to maximize the utility of clinically validated biomarkers and is the cutting edge field to test the ...
Cardelli, P., Hur, M., Somma, S. D.
core +2 more sources
Background Activated immune cells (IC) in the tumor microenvironment (TME) are critical for anti-tumor efficacy. Greater understanding of the dynamic diversity and crosstalk between IC is needed to clarify their association with immune checkpoint ...
Dingwei Ye +16 more
doaj +1 more source
Clinical Features of Rapidly Progressive Alzheimer's Disease [PDF]
Objective: To characterize clinical features, CSF biomarkers and genetic polymorphisms of patients suffering from a rapidly progressing subtype of Alzheimer's dementia (rpAD).
Ahsen, Nico von +7 more
core +1 more source
Integration of Proteomics, Bioinformatics and Systems biology in Brain Injury Biomarker Discovery
Traumatic brain injury (TBI) is a major medical crisis without any FDA-approved pharmacological therapies that have been demonstrated to improve functional outcomes.
Joy eGuingab-Cagmat +3 more
doaj +1 more source
Conditional Screening for Ultra-high Dimensional Covariates with Survival Outcomes [PDF]
Identifying important biomarkers that are predictive for cancer patients' prognosis is key in gaining better insights into the biological influences on the disease and has become a critical component of precision medicine.
Hong, Hyokyoung Grace +2 more
core +3 more sources
The diagnosis of dementia is challenging and early stages are rarely detected limiting the possibilities for early interven-tion. Another challenge is the overlap in the clinical features across the different dementia types leading to difficulties in the
Dilek eInekci +4 more
doaj +1 more source
Adverse drug reactions are a major cause of morbidity and mortality. Of the great diversity of drugs involved in hypersensitivity drug reactions, the most frequent are non-steroidal anti-inflammatory drugs followed by β-lactam antibiotics.
Pedro Ayuso +2 more
doaj +1 more source

